All Klebsiella pneumoniae articles
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NewsVaccinating mothers protects offspring from deadly superbug
Researchers found that a vaccine given to pregnant mice protected their newborn pups from a severe bloodstream infection caused by Klebsiella pneumoniae, a dangerous bacterium that kills thousands of infants in low- and middle-income countries each year and is the leading killer of children globally.
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NewsLab tackles antibiotic resistance across multiple fronts in new trio of studies
To defeat multidrug-resistant superbugs, bacterial defenses must be confronted wherever they may emerge, from basic genetic mutations in a laboratory, to complex real-world transmission in hospital rooms. A new trio of studies demonstrates how an integrated approach might yet expose and overcome these diverse survival mechanisms.
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NewsDogs and cats carry antibiotic-resistant bacteria also found in people, study finds
Pets may carry strains of Klebsiella pneumoniae — a potentially serious bacterium that can cause infections that are also found in humans. The study is the first to map the global genetic makeup of K.pneumoniae carried by domestic dogs and cats, and to compare it on a large scale with the same bacteria in people.
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NewsEngineered macrophages gain enhanced bacteria-targeting ability
A novel membrane interface engineering strategy enables immune cells to specifically recognize, capture and eliminate pathogenic bacteria without genetic modification.
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NewsFrom urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sites
Researchers present a remarkable clinical case that provides new insights into the evolution of bacterial pathogens and presents the concept of heterovirulence, i.e., the simultaneous presence of subpopulations with different levels of virulence within a single infection.
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NewsMicrobiome and cancer: From passive bystanders to active players
A special issue reviews how microbiome science and cancer biology can converge as an integrated front for precision oncology. Articles span topics from hepatocellular carcinoma and colorectal cancer to gastric cancer and pancreatic ductal adenocarcinoma.
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NewsGut microbiome: The hidden architect of liver cancer immunotherapy response
A comprehensive review synthesizes current advances linking gut bacteria to immunotherapy outcomes in hepatocellular carcinoma (HCC), the most common type of primary liver cancer.
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NewsReservoir of drug-resistant germs IDed in national surveillance collaboration
Researchers who screened more than 2,000 samples across 42 states say there is a rapidly evolving, plasmid-driven epidemic of community-associated multidrug resistant Klebsiella pneumoniae across the United States.
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NewsPathogens survive conditions on extraterrestrial locations
Microorganisms from our planet could survive on celestial bodies where water is present, such as Mars, reveals a study focusing on simulated space conditions. Our immune system reacts less effectively to pathogens that have undergone such a simulated space journey.
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NewsFrom pest to useful tool: How wax moth larvae can help reduce animal testing in research
A new study indicates greater wax moth larvae show great potential as a robust and ethically acceptable in vivo model for studying pathogenic bacteria.
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NewsResearcher investigates how a bioengineered peptide can break through harmful bacterial ‘fortresses’ and curb severe infections
A researcher is refining a powerful therapy for drug-resistant bacteria that pierces the gooey coating that anchors and protects such germs from the drugs we take to kill them. She has found that an antimicrobial peptide naturally found in cows weakens the biofilm defenses of Klebsiella pneumoniae bacteria and destroys it.
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NewsGladstone launches Center for PhAIge Therapy to harness AI in the fight against drug-resistant infections
Gladstone Institutes has received funding to establish the Center for PhAIge Therapy, a research center that will develop new phage-based treatments for antibiotic-resistant bacterial infections. The five-year grant makes Gladstone one of three institutions across the country selected to lead this coordinated effort.
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NewsResearchers investigate soil microbes from around the world for new antibacterial drugs
A team of researchers is looking to nature to find microbes that can be used to create new antibiotics to treat the growing threat of drug-resistant bacteria. They will screen soil microbes from around the world to hunt for sources of new antibacterial drugs.
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NewsEurope advances genomic surveillance of CCRE with landmark multi-country study
New survey results provide the most comprehensive genomic picture to date of carbapenem- and/or colistin-resistant Enterobacterales (CCRE) across hospitals in Europe.
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NewsA universal toolkit for editing bacterial DNA
A major collaboration involving nine labs has transferred a particularly useful DNA editing system from E. coli into 14 new species of bacteria, spanning three major branches of the bacterial family tree.
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NewsFoxes and birds could be ‘early warning system’ to survey spread of antibiotic resistance into ecosystems
Wildlife monitoring could alert us to the spread of highly antibiotic resistant bacteria into unexposed ecosystems, highlighting a potential public health strategy.
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NewsCharacteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
A new study investigates the relationship between reduced CD4+T-cell counts and lung infections in immunosuppressed patients admitted to intensive care units (ICUs).
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NewsWhole-genome sequencing is a powerful tool that can pick up on genetic signatures for antimicrobial resistance in UTIs: research
New research to be presented at MLSFF26 reveals whole-genome sequencing as a powerful tool that can distinguish between antibiotic-resistant and susceptible strains of urinary tract pathogens by identifying the specific genetic signatures that confer resistance.
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NewsLow-cost preventive measures could mitigate spread of bacteria causing neonatal mortality
A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.