All Klebsiella pneumoniae articles
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NewsFoxes and birds could be ‘early warning system’ to survey spread of antibiotic resistance into ecosystems
Wildlife monitoring could alert us to the spread of highly antibiotic resistant bacteria into unexposed ecosystems, highlighting a potential public health strategy.
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NewsCharacteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
A new study investigates the relationship between reduced CD4+T-cell counts and lung infections in immunosuppressed patients admitted to intensive care units (ICUs).
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NewsWhole-genome sequencing is a powerful tool that can pick up on genetic signatures for antimicrobial resistance in UTIs: research
New research to be presented at MLSFF26 reveals whole-genome sequencing as a powerful tool that can distinguish between antibiotic-resistant and susceptible strains of urinary tract pathogens by identifying the specific genetic signatures that confer resistance.
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NewsLow-cost preventive measures could mitigate spread of bacteria causing neonatal mortality
A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsResearchers discover how tuberculosis bacteria use a “stealth” mechanism to evade the immune system
New research reveals that mycobacteria release tiny packages called extracellular vesicles that fuse with the membranes of immune cells. These vesicles contain specialized lipids—fatty molecules—that make the cell membrane more rigid.
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NewsStudy links gut bacteria to bloodstream infections in newborns within sub-Saharan Africa for the first time
New research has shown gut and bloodstream infections are caused by the same bacteria giving hope of better prevention and diagnosis of deadly neonatal sepsis.
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NewsApplications of AI in antimicrobial resistance prevention and control
Researchers have published a review shedding light on how AI is revolutionizing the prevention and control of AMR. The article illustrates how machine learning and deep learning are transforming surveillance, diagnosis, treatment optimization, and drug discovery.
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NewsNew collection of bacteria-eating viruses can tackle hospital superbug
An international team of researchers have comprehensively catalogued a new collection of bacteria-eating viruses called phages sourced, in part, from hospital wastewater. The phages have been shown to be effective against different strains of Klebsiella pneumoniae.
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NewsResearchers expand virus-based treatment options for antibiotic-resistant infections
Phages are extremely specific about which strains of a bacterial species they will attack. This has limited their effectiveness against the most antibiotic-resistant strains. To overcome this problem, the research team “trained” the phages by allowing them to evolve together with the bacteria in a controlled laboratory setting for 30 days.
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NewsTime to act and not react: how can the European Union turn the tide of antimicrobial resistance?
Despite determined efforts by countries and healthcare professionals, Europe is not on track to meet four of the five AMR targets set by the EU Council for 2030*, according to data released on EAAD.
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NewsGut microbiota: implications in pathogenesis and potential therapeutic target in primary biliary cholangitis
A new review synthesizes current evidence on gut microbiota dysbiosis in PBC, elucidates its pathogenic mechanisms, and explores its potential as both a diagnostic biomarker and a novel therapeutic target.
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NewsWHO warns of widespread resistance to common antibiotics worldwide
One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments, according to a new World Health Organization (WHO) report.
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NewsNew Center of Excellence to respond to the challenge of antibiotic-resistant bacteria
Boston Children’s Hospital and Tulane University have received $25 million in funding from NIAID/NIH to establish a Center of Excellence for Translational Research (CETR) called IMPACT (Immunization against Multidrug-resistant Pathogens: Activating T Cell Immunity).
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NewsStudy detects multidrug-resistant KPC-producing bacteria in Chilean wastewater for the first time
A team of Chilean researchers has identified, for the first time in the country, the presence of KPC-type carbapenemase-producing bacteria in wastewater samples from the Greater Concepción Metropolitan Area.
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NewsNew sepsis diagnostic could reduce critical time to save patients
A new diagnostic method would confirm sepsis infections earlier, cutting critical hours in the “race against time” to save patients’ lives. The process uses a centrifuge to separate bacteria from blood cells, and automatic microscopy for detection.
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NewsFighting infections with the power of the microbiome
Scientists have discovered that bacteria of the species Klebsiella oxytoca can displace pathogenic bacteria from the gut and want to develop a living biotherapeutic based on this finding. The DZIF is now providing 2.2 million euros in funding for product development.
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NewsHospital superbugs that cause sepsis and meningitis could be hitching a ride on mobile phones
Hospital superbugs that cause sepsis and meningitis could be hitching a ride on mobile phones, allowing them to escape out of healthcare settings and into the community, according to research presented at MLS Future Forum earlier this year.
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NewsFlightpath Biosciences licenses microbiome-sparing antibiotic developed at Illinois
Flightpath Biosciences, Inc., has licensed a class of antibiotics developed at the University of Illinois Urbana-Champaign. The original antibiotic agent, lolamicin, effectively treated bacterial infections in animal models of disease without wiping out beneficial gut microbes.
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NewsGlobal action urgently needed to tackle antimicrobial resistance, experts warn
Scientists have called for urgent changes to the way new antibiotics are developed to address the growing problem of antimicrobial resistance (AMR). They outline the scientific, economic, and regulatory barriers that are slowing progress.