All malaria articles
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First-of-its-kind vaccine expands malaria protection for pregnant women
For the first time, immunization with a malaria vaccine has been shown to protect mothers from malaria during pregnancy and to protect for two transmission seasons without booster doses of vaccine.
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Trojan horse method gives malaria parasites a taste of their own medicine
Researchers have developed a trojan horse method that tricks malaria parasites into ingesting a fatal dose of drugs by exploiting the parasite’s need for cholesterol to survive.
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SRI is developing a new malaria treatment that aims to protect from the disease
The injectable formulation is affordable, easily administered, and could potentially provide months of protection from the potentially fatal disease.
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Scientists identify molecules associated with recurrence in blood samples from malaria patients
Researchers have described for the first time possible biomarkers associated with recurrence of vivax malaria. The study involved analysis of blood samples from volunteers infected by Plasmodium vivax.
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Low birth weight linked to placental malaria in first-time mothers
A new study aimed to determine the prevalence of placental malaria infection, risk factors, types of Plasmodium causing malaria during pregnancy, and its relationship with neonatal birth weight among primigravidae.
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Scientists show the key role of spleen and extracellular vesicles in cryptic malaria infections
A new study has provided new insights into the role of the spleen in malaria, especifically in infections caused by the malaria parasite, Plasmodium vivax.
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Genome research reveals the global march of malaria
Researchers have reconstructed ancient Plasmodium genome-wide data from 36 malaria-infected individuals spanning 5,500 years of human history on five continents, reconstructing the worldwide spread of malaria and its historical impact.
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Researchers turn to AI to help combat malaria in Africa
The project is an international effort that will establish a new research center in Africa to advance malaria research and deploy advanced smart traps for real-time identification of mosquitoes carrying the malaria parasite.
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Breakthrough research identifies mechanism behind drug resistance in malaria parasite
A new study has found that a cellular process called transfer Ribonucleic acid (tRNA) modification influences the malaria parasite’s ability to develop resistance to Artemisinin-based combination therapies.
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Study reveals how climate change will affect malaria transmission
A new model for predicting the effects of climate change on malaria transmission in Africa could lead to more targeted interventions to control the disease, according to a new study.
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An adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.
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Source of pregnancy complications from infections revealed by placenta map
The first panoramic view of infection pathways in the human placenta has been created, which could highlight potential drug targets to develop pregnancy-safe therapies for malaria, toxoplasmosis and listeria.
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Malaria may shorten leukocyte telomeres among sub-Saharan Africans
Researchers have uncovered a potential role of malaria in shortening length of telomeres in white blood cells, known as leukocytes, across sub-Saharan Africa.
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Making transfusion-transmitted malaria in Europe a thing of the past
The current strategy used in Europe to mitigate malaria transfusion risk is efficient with just 10 reported cases over the past 20 years, but current serological tests used to identify “at risk” donors are not sensitive enough to completely eliminate the risk.
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Experimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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Climate change linked surge in malaria transmission could be less than feared
Despite concerns about the potential impact of climate change on increasing malaria risk, there is still limited understanding of how temperature affects malaria transmission – until now.
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Mosquito-borne diseases become a global phenomenon in a warmer, more populated world
An additional 4.7 billion people around the world are predicted to be at risk of malaria and dengue by 2100 if emissions and population growth continue to rise at current levels.
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Experts warn climate change will fuel spread of infectious diseases
A team of infectious diseases experts called for more awareness and preparedness in the medical field to deal with the impact of climate change on the spread of diseases. Their article, published in JAMA, raises the alarm about the emergence and spread of harmful pathogens. The authors ...
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Study reveals impact of malaria interventions through routine sampling of pregnant women
Genomic analysis of the malaria parasite in pregnant women attending their first antenatal visit revealed reduced diversity in areas of southern Mozambique where elimination interventions were implemented.
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Malaria parasite generates genetic diversity using evolutionary ‘copy-paste’ tactic
Plasmodium falciparum, a malaria parasite, uses gene conversion to produce genetic diversity in two surface protein genes targeted by the human immune system.