All malaria articles
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Toxoplasmosis: how the pathogen exploits its own envelope
Researchers have developed a novel imaging technique that allows reliable visualization of the process of endocytosis in Toxoplasma for the first time. The material enters the pathogen through a micropore in its cell membrane.
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Parasite paparazzi take millions of photos of secret malaria proteins
Using millions of microscope images magnified up to 130,000 times, researchers have unraveled the structure of two key proteins in the malaria parasite. With this knowledge, scientists are developing new vaccines that block the transmission of parasites via mosquitoes.
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Tropical diseases: Global health meeting showcases resilience of field under fire
At a moment of monumental challenges for global health, thousands of researchers, clinicians and public health professionals from over 100 countries will gather in Toronto for the 2025 Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).
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Across eight Amazon countries, forests on Indigenous lands reduce spread of 27 diseases
New research finds that municipalities in the Amazon region closest to healthy forests on Indigenous lands face less risk from rising cases of two categories of disease: cardiovascular and respiratory diseases due to forest fires and illnesses.
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Malaria vaccine mimics natural immunity with high precision
A detailed analysis reveals one of the reasons why the R21/Matrix-M malaria vaccine works so well: the antibodies generated following vaccination are indistinguishable from those found in people who have been infected by the parasites.
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Chemical trick could turn losing malaria drug into a winner
A new generation of malaria drugs failed clinical trials, in part because they were hard to swallow. Chemists have remodeled their structures to make them more soluble, while maintaining their effectiveness against drug-resistant parasites.
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Revealed: New vaccine target to block malaria transmission
Researchers have visualised a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.
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Vaccination could mitigate climate-driven disruptions to malaria control
Tropical cyclones in Madagascar lead to sharp spikes in malaria infections – particularly in children – due to interruptions in control efforts, according to a new study. However, newly introduced long-lasting vaccines can help to mitigate these gaps.
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New insights into malaria: Proteins in the blood can reveal the severity of the disease
Researchers have identified over 250 proteins that are strongly affected by malaria, which could help predict the severity of the disease and thus enable faster treatment for the most critical patients.
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Substances isolated from marine sponges show potential for treating malária
In pre-clinical tests, compounds called batzelladins were found to be effective even against strains of Plasmodium that are resistant to conventional antimalarial drugs.
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New strategy developed to engineer high-affinity receptor-containing antibodies against malaria
Researchers have introduced an innovative approach to developing high-affinity receptor-containing antibodies in vitro, offering a promising strategy to combat malaria.
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Paper-based devices diagnose malaria in asymptomatic people
Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.
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Study highlights role of jaundice-associated pigment in protecting against malaria
New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.
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Scholars take a new look at controversial Stateville prison malaria research 75 years ago
Medical ethicists are shining a light on a buried part of the malaria research conducted on inmates at Illinois’ Stateville Penitentiary 75 years ago.
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Targeting malaria parasite’s protein control system could be key to innovative treatments
By inducing protein aggregation in Plasmodium falciparum, researchers have observed considerable disorders in protein homeostasis and a significant reduction in parasite growth.
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New malaria control strategy efficiently kills parasites in the mosquito
A potent combination of antimalarial compounds added to bed nets blocked parasite transmission in mosquitoes while circumventing insecticide resistance, according to a new study.
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Novel molecular maneuver helps malaria parasite dodge the immune system
Researchers have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system. Plasmodium falciparum can shut down a key set of genes, rendering itself “immunologically invisible.”
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The Global Fund to fight AIDS, Tuberculosis and Malaria ‘should step up efforts’
The international community must protect global responses to HIV, tuberculosis (TB), and malaria to serve humanity’s collective interests, according to a new opinion article.
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Study identifies how malaria can lead to childhood cancer
New data has uncovered the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea.
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A 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.