All malaria articles
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Paper-based devices diagnose malaria in asymptomatic people
Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.
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Study highlights role of jaundice-associated pigment in protecting against malaria
New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.
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Scholars take a new look at controversial Stateville prison malaria research 75 years ago
Medical ethicists are shining a light on a buried part of the malaria research conducted on inmates at Illinois’ Stateville Penitentiary 75 years ago.
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Targeting malaria parasite’s protein control system could be key to innovative treatments
By inducing protein aggregation in Plasmodium falciparum, researchers have observed considerable disorders in protein homeostasis and a significant reduction in parasite growth.
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New malaria control strategy efficiently kills parasites in the mosquito
A potent combination of antimalarial compounds added to bed nets blocked parasite transmission in mosquitoes while circumventing insecticide resistance, according to a new study.
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Novel molecular maneuver helps malaria parasite dodge the immune system
Researchers have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system. Plasmodium falciparum can shut down a key set of genes, rendering itself “immunologically invisible.”
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The Global Fund to fight AIDS, Tuberculosis and Malaria ‘should step up efforts’
The international community must protect global responses to HIV, tuberculosis (TB), and malaria to serve humanity’s collective interests, according to a new opinion article.
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Study identifies how malaria can lead to childhood cancer
New data has uncovered the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea.
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A 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.
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Promising new class of antimalarial drugs discovered
A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen. The chromatin remodeler PfSnf2L is a key regulator of genes that play an important role in various stages of the pathogen’s development.
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New study sheds light on the causes of fevers of unknown origin in sub-Saharan Africa
By conducting a retrospective observational study, the causes of fevers of unknown origin (FUO) in sub-Saharan Africa were investigated using conventional diagnostic methods, highlighting the appropriate needs of point-of-care testing in the regions.
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Scientists map essential genome of malaria parasite Plasmodium knowlesi
Comprehensive genetic mapping of Plasmodium knowlesi, a zoonotic parasite that causes malaria, has revealed the genes required for malaria infection of the blood, and those driving drug resistance.
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High uric acid levels - and harmful gut bacteria - linked to deadly outcomes in children with severe malaria
Researchers have uncovered a significant connection between elevated uric acid levels and life-threatening outcomes in children with severe malaria. The study identified hyperuricemia as a potential contributor to increased mortality and long-term neurodevelopmental challenges in children with severe malaria.
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Scientists explain how a compound from sea sponge exerts its biological effects
Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects. Now researchers have a better idea of how it works.
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Chimpanzees are genetically adapted to local habitats and infections such as malaria
Chimpanzees bear genetic adaptations that help them thrive in their different forest and savannah habitats, some of which may protect against malaria, according to a study by an international team.
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Researchers discover novel class of anti-malaria antibodies
A novel class of antibodies that binds to a previously untargeted portion of the malaria parasite could lead to new prevention methods. The most potent of the new antibodies was found to provide protection against malaria parasites in an animal model.
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Global research uncovers critical weakness in malaria parasite
Scientists exploring how immunity develops against Plasmodium falciparum found that broadly reactive antibodies from various individuals consistently bound to the same site on a key virulence protein of the malaria parasite.
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A new approach to predicting malaria drug resistance
Researchers analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance.
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New tool reveals how malaria sticks to red blood vessels
Scientists have unveiled a new tool for studying the highly variable traits that allow malaria parasites to stick to red blood cells and evade the immune system.
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How protective antibodies get in malaria’s way
Researcher’s structural insights help reveal weak spot in parasite’s plan of attack which could help guide vaccine design.