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Tecovirimat is safe but ineffective as treatment for clade II mpox
The antiviral drug tecovrimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial.
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Drug may prevent COVID-19 in exposed people within households, major trial finds
An international clinical trial of the oral antiviral drug, ensitrelvir, which has been proved to prevent COVID-19 cases, was conducted and found to be very effective. The drug will be awaiting for approval before becoming widely available.
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New automated method increases the efficiency of bioactive natural product discovery
In light of the technological advancement in machine learning and bioinformatics tools, researchers developed a fully-automated and integrated platform that enables them to easily identify bioactive natural products in Streptomyces.
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Promising new research shows potential to cure recurrent urinary tract infectionsed
Researchers examine the effectiveness of nanogel as a drug delivery system to direct antibiotics into targeted infected cells to improve UTI treatment.
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Bacteria key to solar-powered method to convert sewage sludge into green hydrogen and animal feed
Scientists have developed an innovative solar-powered method to transform sewage sludge — a by-product of wastewater treatment — into green hydrogen for clean energy and single-cell protein for animal feed.
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Scientists explain energy transfer mechanism in chloroplasts and its evolution
A recent study by Chinese scientists has revealed the intricate molecular machinery driving energy exchange within chloroplasts, shedding light on a key event in the evolution of plant life.
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Food systems, climate change, and air pollution: Unveiling the interactions and solutions
A recent review delves into the complex relationships among food systems, climate change, and air pollution, highlighting the need for sustainable strategies to address these interconnected global challenges.
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Study reveals complex interaction between plants and root microbiota in nutrient utilization
The root microbiota has a profound impact on plant growth and development, health, and adaptability to the environment. So, do the plants also have effects on the root microbiota, and if so, how do the two interact with each other?
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SwRI receives $3 million NASA astrobiology grant to study microbial life in Alaska’s arctic sand dunes
Southwest Research Institute (SwRI) has received a three-year, $2,999,998 million grant from NASA to identify and characterize life and its biosignatures in frozen sand dunes in Alaska, under conditions similar to dune fields on early Mars and Saturn’s moon Titan. Source: Southwest Research Institute The Great Kobuk Sand ...
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Circadian rhythms in tea plant microbiomes shed light on nutrient cycling
A groundbreaking study has uncovered a fascinating connection between the circadian rhythms of tea plants and the microbial communities in their rhizosphere, providing new insights into nutrient cycling.
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Researchers pinpoint shared stress response network between long diverged algae and plants
A research team has compared algae and plants that span 600 million years of independent evolution and pinpointed a shared stress response network using advanced bioinformatic methods.
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Microbiome: Researchers improve bacterial analysis for clinical applications
Different extraction methods can obtain the DNA of certain bacterial species differently, which can significantly distort the determined microbiome composition. Scientists have developed a computer-based method for correcting extraction bias.
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FA Bio licenses two microbes to IFF’s Crop Biologicals division to advance microbial solutions for crop health
FA Bio, a leader in the discovery of sustainable agricultural products, has extended a license agreement on two microbials to IFF’s Crop Biologicals business.
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New discovery and grant to accelerate Strep A vaccine efforts
With a large sum of research funding and multinational contributions, the world’s only Strep A human challenge model will be used to resolve logistical issues and speed up the development of a successful Strep A vaccine.
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Novel enzyme found in gut bacteria could revolutionize prebiotic research
Researchers have discovered a new β-galactosidase enzyme in a human gut bacterium that breaks down and synthesizes previously unexplored glycans, which have prebiotic capabilities to improve gut health.
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Dermatophytes adaptation to the human host exemplified by Microsporum canis
Through comparative genomic analyses, researchers investigated the evolutionary mechanisms that underpin gene expansions to enable dermatophytes, such as Microsporum canis to transition from animal to human hosts.
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Bacteria and minerals work together to detoxify arsenic in contaminated soils
New research shows that the interaction between arsenic-oxidizing bacteria and goethite, a common Fe mineral, significantly accelerates the conversion of arsenic from its highly toxic form, arsenite [As(III)], into the less harmful arsenate [As(V)].
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Early-life gut microbes may protect against diabetes, research in mice suggests
A research discovered that the colonization of a fungus called <i>Candida dubliniensis</i> in the early life gut microbiome of mice, is able to promote growth of pancreatic beta cells in the presence of macrophages to restore blood insulin level and improve metabolic functions, thus reducing risks of type 1 diabetes.
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Transcription factor PoMbp1 promotes the growth of Pleurotus ostreatus by regulating polysaccharide utilisation
A study investigating the growth and development of Pleurotus ostreatus has found that PoMbp1 contains an APSES domain and localizes to the nucleus, indicating it belongs to the fungal-specific APSES transcription factors family.
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Scietnists probe Rhytismataceae on twigs of Rhododendron
Following a study of fungal specimens collected from the twigs of Rhododendron species in China, three new genera were proposed and 21 species residing in 11 genera of Rhytismataceae were delimited, which include 18 new species and three new combinations.