All National University of Singapore articles
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NewsResearchers develop UV and machine learning-aided method to detect microbial contamination in cell cultures
This is the first novel technology that utilises machine learning to analyse unique ultraviolet light “fingerprints” on cell cultures to quickly identify the presence of contamination.
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NewsBreaking antibiotic-resistant bacteria’s protective shields opens door for immune system response
Researchers have made progress in uncovering how Streptococcus pneumoniae constructs its capsule, which serves as a protective shield. This capsule is a primary target for vaccine development.
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NewsGround-breaking technique deploys bacterium to deliver drugs directly to the brain
A landmark study using the nasal bacteria technique promises new treatments for neurological disorders by bypassing the blood-brain barrier.
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NewsA realistic ‘micro-gut’ model reflects the relationship between gut microbes and human diseases
An innovative and more physiologically relevant 3D micro-gut model, known as Gut-Microbiome on a chip (GMoC), provides an in-depth understanding of the complex interactions between the microbial community within the gut microbiome and their impacts on human gut health.
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NewsStudy uncovers how dengue virus hijacks human plasmin for infection
Scientists characterized and revealed the correct structural bindings between dengue virus and human plasmin from mosquito blood meal to allow better understanding in dengue virus pathogenesis.
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NewsScientists lift lid on Salmonella dry surface biofilm
Food scientists have revealed key characteristics of the foodborne pathogen Salmonella dry surface biofilm (DSB), a previously overlooked type of biofilm that commonly exists in dry food processing environments.
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NewsBioengineered yeast microbes as targeted drug delivery systems
Researchers from the Yong Loo Lin School of Medicine (NUS Medicine) have developed a groundbreaking way to engineer yeast (Saccharomyces cerevisiae) to create microbial communities that can perform complex tasks and self-regulate their composition in response to external signals. Source: Alexander Klepnev Baker’s yeast cells. Calcofluor ...
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NewsThe secret of healthy aging may lie in our gut
A new study has revealed that gut bacteria may play a key role in aging, and that specific microbes could be targeted to promote healthy aging.
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NewsMulti-omics strategy reveals how insect parasite fungus ameliorates sepsis-associated acute kidney injury
Scientists have found that Cordyceps sinensis significantly ameliorates renal injury and inflammation in sepsis-associated acute kidney injury (S-AKI) by regulating mitochondrial energy metabolism and macrophage polarization.
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NewsResearchers discover new Candida auris – a possible global public health threat
Researchers have discovered a new clade (or type) of Candida auris, bringing the number of clades known globally to a total of six.
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News$14.8 million grant supports Illinois-Singapore partnership on precision fermentation for food
The team has received a five-year, $14.8 million-dollar grant to develop the Centre for Precision Fermentation and Sustainability (PreFerS), focusing on enhancing the reliable, cost-effective production of safe, nutritious, and appetizing foods.
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NewsVaccine approach offers promise to induce longer-lasting protective immunity against COVID-19
A scientific team has engineered a COVID-19 vaccine that induced – in pre-clinical models – very long-lasting, protective immunity against SARS-CoV-2 virus with a single-shot immunisation.
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NewsStudy identifies immunity threshold for protection against COVID-19 in children
Researchers have found rather than antibodies, other arms of the immune system – T cells and memory B cells – provide durable protection against symptomatic SARS-CoV-2 infection in children.
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NewsBreakthrough antibiotic shows promise against obstinate mycobacterial infections
Researchers assemble a new antibiotic candidate, COE-PNH2, offering a more effective therapeutic option against hard-to-treat mycobacterial lung diseases.
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NewsResearchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
A new class of antibiotics not only shows promise against a broad array of bacterial infections but can also evade the dreaded resistance that has been rendering our current generation of first-line antibiotics ineffective.
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NewsScientists construct a synthetic yeast genome
The yeast genome contains redesigned chromosome sequences that can shed light on the impact of genetic variations on individual traits and potentially be used to reveal the causes of genetic diseases
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News Nano-sized cell particles are promising tool in treating infectious diseases
In a new study, extracellular vesicles were found to inhibit the viral infection of COVID-19 and potentially other infectious diseases.
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NewsResearchers unlock power of genetic glycoengineering to advance vaccine tech
A novel glycoengineering platform is poised to revolutionise future production of vaccines and therapeutics to fight infectious diseases.
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NewsGut inflammation caused by substance secreted by microbe
A rare subtype of the world’s most common parasite, Blastocystis, has been found to produce a unique by-product of its metabolism, which can cause gut inflammation under normal gut conditions.