All Research News articles – Page 75
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Changing the gut microbiome boosts health outcomes for people newly diagnosed with metastatic kidney cancer
Researchers have developed a novel use of biotherapeutic product CBM588 in the treatment of cancer; new research suggests the agent adjusts people’s microbiome, possibly leading to enhanced effectiveness of FDA-approved cancer immunotherapies.
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Breakthrough research makes cancer-fighting viral agent more effective
Researchers from Aarhus University have made a significant breakthrough by discovering that the drug 4-OI can enhance the effectiveness of a cancer-fighting viral agent. This may lead to treatment of cancers that are otherwise resistant to therapies.
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Bird flu stays stable on milking equipment for at least one hour
Bird flu, or H5N1 virus, in unpasteurized milk is stable on metal and rubber components of commercial milking equipment for at least one hour, increasing its potential to infect people and other animals, report researchers.
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Coumarin glycosides reverse enterococci-facilitated enteric infections
Researchers have developed a dietary therapeutic for enterococci-mediated infections.
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Common respiratory infections may have protected children from COVID-19, study suggests
Analyzing nasal swabs taken during the pandemic, researchers suggest that the frequent presence of other viruses and bacteria may have helped to protect children from the worst effects of COVID-19 by boosting their immune systems.
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Researchers thwart resistant bacteria’s strategy
Researchers have discovered a weakness in Pseudomonas aeruginosa with the potential to become the target for a new way to attack it.
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Degradation of cell wall key in the spread of resistance
A new study shows how an enzyme breaks down the bacteria’s protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
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Researchers harness intratumoral microbiome against colorectal cancer
Scientists have established a microbiota-targeted drug delivery system that exhibits high efficiency in colorectal cancer targeting and colon retention.
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AI helps mine genetic elements from ancient genomes to tackle antibiotic resistance
Scientists have developed an artificial intelligence tool to mine the vast and largely unexplored biological data—more than 10 million molecules of both modern and extinct organisms— to discover new candidates for antibiotics.
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Potato blight pathogen probably originated in the Andes before spreading worldwide
A new study challenges the common theory that the devastating potato blight pathogen Phytophthora infestans originated in Mexico. Researchers meticulously reconstructed its global migration history and found it likely originated in the South American Andes before spreading globally. Source: Gareth James Famine memorial, Dublin. The potato blight pathogen ...
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Fertilizer strategies can shape microbial communities in the rhizosphere
Fertilizer strategies can play a key role in the diversity of microbial communities in the crop rhizosphere, according to a new study.
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New findings may fix the replicability crisis in microbiome research
Scientists report that daily fluctuations in the gut alter the microbiome so significantly that different bugs populate it in the morning and in the evening.
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Imaging measles fusion process reveals pathway to powerful weapon
Scientists have harnessed an imaging technique called cryo-electron microscopy to show—in unprecedented detail—how a powerful antibody can neutralize the measles virus before it completes the process of fusing into the host cell membrane.
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We should help coral microbial symbionts evolve heat tolerance in the lab, researchers say
Researchers discuss the potential of improving corals’ chances by inducing the evolution of heat tolerance in their symbionts—the mutualistic microbes that provide corals with nutrients in exchange for shelter and that are expelled during coral bleaching.
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Mycena mushrooms have ’massively expanded’ genomes to make them more adaptable
A study of multiple Mycena mushroom species, also known as ‘bonnets’, reported in the journal Cell Genomics on June 27 has found that they have unexpectedly large genomes. Source: Arne Aronsen Mycena epipterygia While the mushrooms had been thought to live by degrading dead organic material alone, ...
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Chemotherapy disrupts gut microbiome in patients with breast cancer
Patients treated with chemotherapy who showed decreases in cognitive performance also had reductions in the diversity of their gut microbiome, a new study has found.
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Survey finds many have misconceptions about sexually transmitted infection risk
Sexually transmitted infections (STIs) are on the rise in the U.S., including an 80% increase in syphilis over a five-year period, but a new survey finds many Americans have misconceptions on how STIs are spread and who should be treated.
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Marine natural product derivative offers new therapeutic strategy to inhibit enterovirus A71 replication
Researchers revealed that the inhibition of enterovirus A71 (EV-A71) replication can be achieved by targeting the human coatomer subunit zeta-1 (COPZ1) using a marine natural product derivative known as MPA-CF3.
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Specific bacteria in your gut are involved in compulsive eating and obesity
Researchers have identified specific bacteria in the gut that are associated with both mice and humans developing an addiction to food that can lead to obesity. They have also identified bacteria that play a beneficial role in preventing food addiction.
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Diagnostic stewardship approach to C. diff reduces unnecessary testing
Revised rules for when Clostridioides difficile tests could be ordered helped to reduce inappropriate testing by 20%, which in turn can help rein in the overtreatment of patients.