All sepsis articles
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NewsLow-cost preventive measures could mitigate spread of bacteria causing neonatal mortality
A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsSepsis study IDs simple ways to save lives in Africa
Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a new study reveals. It found that more than half of the hundreds of patients enrolled in the study had TB and that immediate treatment increased their chances of survival significantly.
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NewsShould younger and older people receive different treatments for the same infection?
Scientists find the mechanisms young mice use to fight sepsis become disadvantageous in older age, suggesting age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
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NewsStudy links gut bacteria to bloodstream infections in newborns within sub-Saharan Africa for the first time
New research has shown gut and bloodstream infections are caused by the same bacteria giving hope of better prevention and diagnosis of deadly neonatal sepsis.
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NewsIncreased risk of severe bacterial infection after high teenage BMI
High BMI and poor physical fitness during later adolescence increase the risk of both contracting and dying from sepsis and other severe bacterial infections in adulthood, according to a study.
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CareersSummer studentship: Oliver probes AMR in neonatal sepsis - and use of novel bacterial screening methods.
Oliver Spiller-Boulter, from Cardiff, reports back on his AMI-sponsored summer studentship which examined antimicrobial resistance (AMR) in neonatal sepsis and the use of novel bacterial screening methods.
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NewsHospital bug jumps from lungs to gut, raising sepsis risk
A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals.
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NewsMaternal health programme cuts infection deaths by 32%
A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women’s lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.
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NewsNew editorial urges clinicians to address sex-based disparities in sepsis treatment
Standardized antibiotic dosing frequently ignores patient-level variability. A newly published editorial is calling attention to how biological sex and gender inequities contribute to suboptimal sepsis treatment, potentially compromising outcomes for women.
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NewsRebalancing the gut: how AI solved a 25-year Crohn’s disease mystery
Researchers have settled a decades-long debate surrounding the role of the first Crohn’s disease gene to be associated with a heightened risk for developing the auto-immune condition.
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NewsType 2 diabetes may double risk of sepsis, large community-based study suggests
Living with type 2 diabetes (T2D) may double the risk of developing sepsis—with those aged younger than 60 years and men particularly susceptible, according to a long-term community-based study in Australia.
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NewsCARB-X backs neonatal sepsis diagnostic platform by Quantamatrix
CARB-X has awarded QuantaMatrix Inc. US$2.85M to execute a workplan to develop its rapid diagnostic platform to detect sepsis, especially in vulnerable neonates. The test aims to deliver results within just 6 hours from very small blood samples of 1 to 2 milliliters.
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NewsRegional differences in antibiotic use in newborns
There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study. The researchers want to call attention to overuse as well as highlight good examples.
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NewsAntibiotic resistance predicts higher mortality risk in 17-year follow-up
A population-based study finds that in addition to antibiotic use, diet, sex, living environment, income level and certain gut bacteria are associated with a higher burden of resistance.
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NewsFrom COVID to cancer, new at-home ‘coffee-ring’ test spots disease with startling accuracy
A new, low-cost biosensing technology could make rapid at-home tests up to 100 times more sensitive to viruses like COVID-19. The diagnostic could expand rapid screening to other life-threatening conditions like prostate cancer and sepsis as well.
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NewsYeast produces human DNase1 for the first time
The protein DNase1 is used to treat cystic fibrosis but it takes considerable effort and cost to produce it in immortalized hamster cells. Researchers have now produced it in yeast cells for the first time.
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News1 in 5 older adults get infections after heart surgery, and women have a 60% higher risk
One in five older adults gets an infection up to six months after heart surgery, with women far more likely to develop one, according to two studies which examined thousands of cases of coronary artery bypass grafting.
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CareersHow frontline innovation from military labs can fight antimicrobial resistance worldwide
CEO at Presymptom Health, Dr. Iain Miller reveals how research in military laboratories - born out of battlefield demands - is now yielding innovative tech that allows for faster and more accurate detection of infections, even before symptoms appear.
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NewsStaphylococcus aureus thwarts vaccines by turning on a protein that halts immune response
Approximately 30 clinical trials to date have failed to result in an effective human vaccine for Staphylococcus aureus but researchers have now identified a key reason for these failures, indicating that it may be possible to modify the vaccines to work in humans.