All sepsis articles
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News
1 in 5 older adults get infections after heart surgery, and women have a 60% higher risk
One in five older adults gets an infection up to six months after heart surgery, with women far more likely to develop one, according to two studies which examined thousands of cases of coronary artery bypass grafting.
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Careers
How frontline innovation from military labs can fight antimicrobial resistance worldwide
CEO at Presymptom Health, Dr. Iain Miller reveals how research in military laboratories - born out of battlefield demands - is now yielding innovative tech that allows for faster and more accurate detection of infections, even before symptoms appear.
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Staphylococcus aureus thwarts vaccines by turning on a protein that halts immune response
Approximately 30 clinical trials to date have failed to result in an effective human vaccine for Staphylococcus aureus but researchers have now identified a key reason for these failures, indicating that it may be possible to modify the vaccines to work in humans.
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News
Biomarker test could significantly reduce antibiotic use in sepsis
A major UK patient trial of a new biomarker testing protocol for sepsis, has shown it is possible to safely stop antibiotic treatment earlier than current care.
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Understanding neonatal infectious diseases in low- and middle-income countries
Researchers have conducted an in-depth study on the epidemic status, secular trends, and risk factors of 15 common neonatal infectious diseases across low- and middle-income countries (LMICs) from 1990 to 2019.
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News
Faster measurement of response to antibiotic treatment in sepsis patients using Dimeric HNL
The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis.
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AI tackles huge problem of antimicrobial resistance in intensive care
Artificial intelligence (AI) can provide same-day assessments of antimicrobial resistance for patients in intensive care – critical to preventing life-threatening sepsis.
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Scientists develop tool to predict sepsis in apparently healthy newborns
This discovery could help with earlier recognition of critically ill babies to implement life-saving treatment.
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News
New microfluidic chip method developed for sepsis prognosis and evaluation
Researchers have developed a new prognostic evaluation method for sepsis patients using a microfluidic concentration gradient chip.
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Half of all patients with sepsis die within two years
Half of all patients with sepsis admitted to an emergency medical department died within two years, according to researchers investigating factors that could predict outcomes for these patients.
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News
Wound peptides can help detect dangerous infections more quickly
After identifying unique peptide patterns and changes in these patterns based on different types of bacteria in wounds, researchers can now assess the severity of the infection, a new study reveals.
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A human-centered AI tool to improve sepsis management
A proposed artificial intelligence tool to support clinician decision-making about hospital patients at risk for sepsis has an unusual feature: accounting for its lack of certainty and suggesting what data it needs to improve its predictive performance.
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News
Sepsis patients could get the right treatment faster, based on their genes
New research uncovers how different people respond to sepsis based on their genetic makeup, which could help identify who would benefit from certain treatments and lead to the development of targeted therapies.
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News
Researchers discover how a deadly strain of salmonella fine-tunes its infection tactics
A new study investigates how pathogens like salmonella change their disease characteristics under fluid shear conditions like those they encounter in our bodies during infection.
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AI enables faster, more effective antibiotic treatment of sepsis
Sepsis is a life-threatening infection complication and accounts for 1.7 million hospitalizations and 350,000 deaths annually in the U.S. Fast and accurate diagnosis is critical, as mortality risk increases up to 8% every hour without effective treatment. Source: Ilanaer42 However, the current diagnostic standard is reliant on ...
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News
Nasal microbiota is potential diagnostic biomarker for sepsis
The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study.
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Precision medicine for sepsis in children within reach
Researchers used artificial intelligence to analyze a large set of clinical data and find a distinct group of patients who might respond better to targeted sepsis treatments.
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News
Researchers identify factors that heighten risk for catheter-associated urinary tract infections and sepsis
Fibrinolytic deficiencies, or conditions that cause overactivation of the protein fibrin, can increase the risk of developing severe and persistent CAUTIs, a new study finds.
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News
New antibiotic kills pathogenic bacteria, but spares healthy gut microbes
Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.
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News
Vaccine development program aims to prevent sepsis in newborns
Researchers have been awarded $3.96 million to develop a maternal vaccine that prevents sepsis caused by Klebsiella pneumoniae in newborns and infants.