All sepsis articles
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NewsDietary tryptophan prevents sepsis
Dietary tryptophan protects against sepsis through gut microbiota-derived metabolites which enhance macrophage bacterial phagocytosis.
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NewsNew approach cuts sepsis diagnosis from days to hours
A research team has developed a way to condense the days-long sepsis diagnosis timeline to just hours, a method which could help clinical decision-making that avoids worsening antibiotic resistance in the bacterial strains causing infections.
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NewsWidely used early warning score may help guide the urgency of antibiotic treatment for suspected sepsis
Large cohort study suggests the National Early Warning Score (NEWS2) may provide a more comprehensive framework than current guidance for determining which patients with suspected sepsis benefit from immediate antibiotics.
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NewsThe hidden danger of cat lick – a case report with reconstruction
Capnocytophaga canimorsus is a bacterium found in the mouths of dogs and cats. It can cause severe sepsis, and in some cases leads to purpura fulminans (PF), a condition that triggers rapid tissue necrosis.
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NewsTime for an AI checkup: Flaw found in machine learning for sepsis treatment
Researchers found a flaw in many peer-reviewed studies using the AI method known as reinforcement learning as a theoretical guide for the treatment of sepsis. If these flawed systems for sepsis treatment were deployed in a healthcare setting, they would recommend either overtreatment or undertreatment in nearly half of patient states.
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NewsInfections are major ‘health hazard’ for people with diabetes
Infections should be considered a “health hazard” in people living with diabetes, with experts warning that current clinical guidelines fail to reflect a substantial but under-recognised burden of illness, hospitalisation and death. People living with type 1 diabetes, type 2 diabetes and prediabetes face higher risks of infection compared to those without diabetes.
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NewsGut microbe found to worsen sepsis by triggering hyperinflammatory immune responses
Researchers have identified a specific gut microbial group that can dramatically worsen sepsis by excessively sensitizing immune cells. Genetically identical mice showed strikingly different infection outcomes depending on the composition of their gut microbiota.
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NewsNASCAR star’s death shows how sepsis can kill anyone if not caught
Kyle Busch won more races than any driver in NASCAR history. But his own race ended far too soon, cut short by sepsis at the age of 41 after a case of pneumonia.
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NewsFDA approves early warning system for sepsis
An early warning system for sepsis, one of the deadliest infections for hospital patients, has been approved for use by the FDA, one of the first AI-based medical tools to get clearance. The tool detects sepsis hours faster than doctors and has reduced deaths by nearly 20%.
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NewsLow-cost preventive measures could mitigate spread of bacteria causing neonatal mortality
A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsSepsis study IDs simple ways to save lives in Africa
Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a new study reveals. It found that more than half of the hundreds of patients enrolled in the study had TB and that immediate treatment increased their chances of survival significantly.
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NewsShould younger and older people receive different treatments for the same infection?
Scientists find the mechanisms young mice use to fight sepsis become disadvantageous in older age, suggesting age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
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NewsStudy links gut bacteria to bloodstream infections in newborns within sub-Saharan Africa for the first time
New research has shown gut and bloodstream infections are caused by the same bacteria giving hope of better prevention and diagnosis of deadly neonatal sepsis.
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NewsIncreased risk of severe bacterial infection after high teenage BMI
High BMI and poor physical fitness during later adolescence increase the risk of both contracting and dying from sepsis and other severe bacterial infections in adulthood, according to a study.
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CareersSummer studentship: Oliver probes AMR in neonatal sepsis - and use of novel bacterial screening methods.
Oliver Spiller-Boulter, from Cardiff, reports back on his AMI-sponsored summer studentship which examined antimicrobial resistance (AMR) in neonatal sepsis and the use of novel bacterial screening methods.
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NewsHospital bug jumps from lungs to gut, raising sepsis risk
A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals.
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NewsMaternal health programme cuts infection deaths by 32%
A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women’s lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.
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NewsNew editorial urges clinicians to address sex-based disparities in sepsis treatment
Standardized antibiotic dosing frequently ignores patient-level variability. A newly published editorial is calling attention to how biological sex and gender inequities contribute to suboptimal sepsis treatment, potentially compromising outcomes for women.
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NewsRebalancing the gut: how AI solved a 25-year Crohn’s disease mystery
Researchers have settled a decades-long debate surrounding the role of the first Crohn’s disease gene to be associated with a heightened risk for developing the auto-immune condition.