All Synthetic Biology articles
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Scientists develop eco-friendly, nylon-like plastic using microorganisms
Scientists have developed microbial strains through systems metabolic engineering to produce various eco-friendly, bio-based poly(ester amide)s from glucose derived from biomass sources such as waste wood and weeds.
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Researchers achieve de novo biosynthesis of plant lignans using synthetic yeast consortia
Researchers have achieved the biosynthesis of the antiviral ingredient lignan glycoside in yeast Saccharomyces cerevisiae. By mimicking the spatial and temporal regulation of plant biosynthesis, they designed a system with obligated mutualism, enabling metabolic division of labor among different yeast strains.
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Rice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
An interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track gene transfer in microbial communities, providing new insights into how genes move across species.
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Researchers reveal key mechanism behind bacterial cancer therapy
A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.
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Synthetic microbiome therapy suppresses bacterial infection without antibiotics
A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans. Clostridioides difficile is a bacterium that can cause severe diarrhea, abdominal pain and colon inflammation.
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No more antibiotics? Scientists pioneer a safer way to protect cultured meat
A new study explores the use of Random Antimicrobial Peptide Mixtures (RPMs) as a safe and effective alternative to antibiotics in cultured meat production. These synthetic peptide cocktails eliminate bacterial contamination without harming stem cell viability or contributing to antibiotic resistance.
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Researchers engineer biological reaction crucibles to rapidly produce proteins
Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.
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Scientists recode the genome for programmable synthetic proteins
Synthetic biologists were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed enabling the production of new classes of synthetic proteins.
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Researchers discover new way to customize living materials for tissue engineering, drug delivery and 3D printing
Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to deformation forces like stretching or compression.
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Scientists develop groundbreaking biosensor for rare earth element detection
A prototype for an innovative biosensor can detect rare earth elements and be modified for a range of applications. Synthetic scientists engineered proteins to create molecular nanomachines that generate easily detectable signals when they selectively bind to Lns.
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Final synthetic yeast chromosome unlocks new era in biotechnology
A team of researchers has successfully synthesised the very first yeast chromosome using specialised genome-editing technique that provides insights for synthetic biology and biomanufacturing fields.
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Scientists synthesize a promising mushroom-derived compound
Researchers have successfully developed the first method to synthesize inaoside A, a compound derived from the edible mushroom Laetiporus cremeiporus.
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Careers
Towards space plastics - and solving a few Earth problems en route
Dr Nils Averesch, Assistant Professor of Space Biology at the Space Life Science Laboratory, Cape Canaveral, reveals how his research on microbial plastic production could pave the way for thriving human settlements in space.
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Scientists offer user manual for yeast’s genetic switches
Scientists have found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production using yeast.
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Researchers call for global discussion about possible risks from ‘mirror bacteria’
A group of researchers has published new findings on potential risks from the development of mirror bacteria — synthetic organisms in which all molecules have reversed chirality (i.e. are ‘mirrored’).
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Scientists engineer new enzyme to produce synthetic genetic material
Researchers have engineered an efficient new enzyme that can produce a synthetic genetic material called threose nucleic acid. The ability to synthesize artificial chains of TNA advances the discovery of therapeutic options to treat cancer and other diseases.
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Peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.
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Study probes industrial scale lactoferrin production with synthetic biological systems
A new study explores the innovative technologies developed to increase lactoferrin production in order to meet market demand in food, pharma, and cosmetics.
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Scientists team up to create synthetic process for antibiotic drug discovery
Researchers will team up to explore and develop a novel platform or chemical process for synthesizing antibiotic compounds, thanks to a $125,000 grant.
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Microbe dietary preferences influence the effectiveness of carbon sequestration in the deep ocean
The movement of carbon dioxide (CO2) from the surface of the ocean to the deep ocean depends on a number of seemingly small processes - including the dietary preferences of bacteria that feed on organic molecules called lipids.