All University of Copenhagen articles
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News
Kiss goodbye to deadly disease – new research finds ‘Pac-Man’ antibodies for killer parasite
Researchers have successfully produced antibodies that kill the parasite carried by the ‘kissing bug’ that causes the potentially deadly Chagas disease. The research is a vital step towards the development of the first effective vaccine.
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Microbiome breakthrough: Gut bacterium may hold key to future treatments for widespread chronic diseases
Scientists have identified a common specific gut bacterial strain that may open the door to a new class of therapeutics. This bacterium produces two proteins that influence the body’s hormonal balance and affect weight, bone density, and blood sugar levels.
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Bacteria from cows show promising results in treating MRSA infections
Cows carry a bacterium, Staphylococcus simulans, that could become an effective weapon against increased antibiotic resistance. Signaling molecules from this bacterium can treat infections caused by MRSA bacteria as effectively as antibiotics.
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Emerging viral threats combatted by a potent new dual lipid kinase inhibitor
Lipid kinases play a critical role in cell signalling and membrane trafficking by phosphorylating lipid molecules in the body. The inhibition of two of these lipid kinases, PIKfyve and PIP4K2C, could be beneficial in the treatment of diseases, particularly emerging viruses.
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Large-scale DNA study maps 37,000 years of disease history
A new study maps infectious diseases across millennia and offers new insight into how human-animal interactions permanently transformed our health landscape.
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Vaccine disguised as a virus tricks the body into stronger immunity
A simple addition to mRNA vaccines can significantly enhance their effectiveness. Scientists have shown that mice develop a stronger and longer-lasting immune response when the mRNA vaccine is disguised as virus-like particles.
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Biosynthetic pathway discoveries mean we can halve the price of costly cancer drug
Researchers have identified the enzymes responsible for the two critical final steps in the biosynthetic pathway that makes the chemotherapy drug Taxol active as a drug, potentially opening it up to biotech based production.
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Bacteria use ancient war trick to outsmart viruses – and it could help us fight superbugs
Scientists have discovered a new type of immune defense in E. coli bacteria that turns viral infection machinery against the virus itself. They’ve named it Kongming after the Chinese military strategist who famously used enemy weapons to defeat his foes.
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Nitrogen fixation on marine snow particles is widespread in the world's oceans
Researchers have shown that bacteria attached to marine snow particles can fix N2 over a wide range of temperatures in the global oceans, from the tropics to the poles, and from the surface to the abyss, accounting for about 10% of the overall N2 fixation in oceans.
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Carrots may help regulate blood sugar and improve gut flora
Current research reveals that carrots may help regulate blood sugar and improve gut flora – a combination that could potentially benefit individuals with type 2 diabetes.
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Careers
Van Hung Vuong Le: my year as a Junior Editor with Letters in Applied Microbiology
One year into our Junior Editor training programme with Letters in Applied Microbiology, Van Hung Vuong Le from the University of Exeter reflects on the experience.
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How protective antibodies get in malaria’s way
Researcher’s structural insights help reveal weak spot in parasite’s plan of attack which could help guide vaccine design.
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Human antibodies could prevent the malaria parasite from causing life-threatening infections
Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year – most of them African children under five. In a new study, published in the journal Nature, researchers from EMBL Barcelona, the University of Texas, the ...
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How do microbiomes influence the study of life?
Researchers from the awardwinning One Health Microbiome Center reveal how holobiont biology underpins a holistic understanding of how life’s forms and functions, from human disease to agricultural output, depend upon the relationships between microbes and hosts.
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Researchers hope to develop novel drugs for gastrointestinal disorders by fermenting feces
In a new study, researchers have been cultivating ‘good viruses’ from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants and improve this life-saving treatment through standardization.
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Genomic signatures of domestication in a fungus obligately farmed by leafcutter ants
Researchers have harnessed cutting-edge genome sequencing approaches to decode the genetic building blocks that comprise Leucoagaricus gongylophorus, the fungus farmed by leafcutter ants.
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Scientists close in on mystery of deadly Hep C virus
A new study by a cross-disciplinary research team has identified the protein complex at the surface of the hepatitis C virus that enables it to bind to human cells, opening a pathway to vaccine candidates that can prevent the virus from infecting the cells.
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The plague may have caused the downfall of the Stone Age farmers
Ancient DNA from bones and teeth hints at a role of the plague in Stone Age population collapse. Contrary to previous beliefs, the plague may have diminished Europe’s populations long before the major plague outbreaks of the Middle Ages.
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Current strategies ineffective in controlling Salmonella Dublin in Danish cattle
Researchers have shown that, despite stringent movement restrictions among Danish cattle farms, Salmonella Dublin continues to propagate, indicating that current strategies are insufficient to curb the spread of the disease.
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Dietary fibers make our gut bacteria behave healthily
Researchers have discovered that dietary fibres play a crucial role in determining the balance between the production of healthy and harmful substances by influencing the behaviour of bacteria in the colon.