All University of Groningen articles
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News
New research reveals how bacteria export the building blocks of biofilms
Chemists examined how the polysaccharide “Pel” – a central component of many biofilms – is exported out of the cell by the pathogen P. aeruginosa and describe the structure of the so-called PelBC export complex, which represents the last station in the cell before “Pel” is released.
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Green light activates this antibiotic only where it’s needed
To make a more efficient antibiotic treatment, researchers have modified penicillin so that it’s activated only by green light. In early tests, the approach precisely controlled bacterial growth and improved survival outcomes for infected insects.
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Scientists ID previously unknown enzymes that can produce potentially antimicrobial agents
Micro-organisms generate potential agents for combating bacteria and fungi. Researchers have identified and optimized enzymes that can specifically generate a certain functional group of these natural substances, expanding the toolkit of potential agents.
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Chemists pioneer metallodrug-antibiotic combination strategy to combat superbugs
A combination of different types of antibiotics with bismuth-based drugs, such as Pepto-Bismol, disrupts bacterial iron homeostasis, effectively restoring the bactericidal function of multiple antibiotics.
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Temperature could be the new weapon in the battle against antibiotic resistance
Scientists have found that a small increase in temperature from 37 to 40 degrees Celsius drastically changes the mutation frequency in E. coli bacteria, which facilitates the development of resistance.
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Scientists discover a new way of sharing genetic information in a common ocean microbe
<i>Prochlorococcus</i>, the world’s most abundant photosynthetic organism, reveals a gene-transfer mechanism that may be key to its abundance and diversity.