All University of Manchester articles
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Ignore antifungal resistance in fungal disease at your peril, warn top scientists
Without immediate action, humanity will potentially face further escalation in resistance to fungal disease, a renowned group of scientists from the across world has warned.
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Fungus uses surface protein of its spores to weaken human immune system
An international research team discovered a special enzyme on the surface of the spores of Aspergillus fumigatus apparently suppresses the release of pro-inflammatory substances by immune cells, making it easier for the pathogen to spread in the tissue.
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Scientists discover superbug’s rapid path to antibiotic resistance
Researchers have discovered how a hospital superbug Clostridioides difficile (C.diff) can rapidly evolve resistance to vancomycin. In less than two months the bacteria could develop resistance to 32 times the initial antibiotic concentration.
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Biocides are a useful tool to combat antibiotic resistance but appropriate use is vital, scientists suggest
A recent review in Sustainable Microbiology discusses how the use of biocides can promote well-being but must only be used when there are clear benefits.
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Orchids support seedlings through ‘parental nurture’ via shared underground fungal networks
Early stage orchid seedlings germinate and thrive near to adult plants due to a kind of parental nurture using underground fungal networks, a new study has found.
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Microbes linked to oilfield reservoir souring prove remarkably persistent
New research being presented at the Letters in Applied Microbiology ECS Research Symposium shines a fresh light on the persistence of microbial communities that are linked to the contamination of oilfield reservoirs - a problem that costs the energy sector billions of dollars a year.
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Biofilms play key role in reducing sensitivity to ionic silver in wound pathogens.
Bacterial pathogens in wounds that have been treated with ionic silver can adapt and become less sensitive - thanks to biofilm formation.
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Climate change disrupts vital ecosystems in the Alps
Reduced snow cover and shifting vegetation patterns in the Alps, both driven by climate change, are having major combined impacts on biodiversity and functioning of ecosystems in the high mountains, according to new research published today.
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Mathematicians use AI to identify emerging COVID-19 variants
Scientists have developed an AI framework that can identify and track new and concerning COVID-19 variants and could help with other infections in the future.
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Scientists develop new biocontainment method for industrial organisms
Researchers have found that by adding an estradiol-controlled destabilising domain degron (ERdd) to the genetic makeup of baker’s yeast, they can control survival of the organism.
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New estimate doubles likely deaths from fungal disease globally
The annual total of deaths from fungal disease worldwide has risen to 3.75 million, double the previous estimate, according to a new study.
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Crop spray could lead to mass resistance in new-generation antifungal treatments
An agricultural fungicide approved in the US and currently under consideration by authorities worldwide could have a devastating effect on a new drug for one of world’s deadliest infectious diseases.
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Patients can pause immune-suppressing medicines for COVID-19 booster vaccine
A major clinical trial shows that people with inflammatory conditions are able to improve the antibody response from a COVID-19 booster vaccination by interrupting their treatment for two weeks immediately after having the vaccine.
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New study considers risks of colistin and carbapenem resistance posed by aquatic farms
Aquatic farms could serve as a potential reservoir of colistin and carbapenem resistance, a new study warns. The review, by researchers at the University of Manchester, ‘An Update on the Prevalence of Colistin and Carbapenem-Resistant Gram-Negative Bacteria in Aquaculture: an Emerging Threat to Public Health’, has been accepted by the ...
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Study solves mystery behind bacteria’s extensive weaponry
A new study has shed light on why certain species of bacteria carry astonishing arsenals of weapons. The findings could help us to engineer microbes that can destroy deadly pathogens, reducing our reliance on antibiotics.
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Study links deprivation with risk of dying from sepsis
The most socioeconomically deprived groups in society are nearly twice as likely to die from sepsis within 30 days, researchers have found.
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Researchers to benefit from £18 million investment in world-class frontier bioscience
Researchers at The University of Warwick are among four world-class teams receiving a share of £18 million to pursue transformational bioscience research programmes.
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Frequent use of antibiotics linked to severe Covid outcomes
Frequent and diverse use of antibiotics may be associated with developing more severe outcomes after a COVID-19 infection, including death, a new study has shown.
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Flaws in COVID-19 weather studies spark call for improved publishing practices
Research that linked the weather with the spread of COVID-19 during the pandemic was inaccurate and poorly scrutinised by fellow scientists, suggests a new study.
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A polychromatic light device has an antibacterial effect in blood
Polychromatic light administered by device into blood delivers a moderate antibacterial effect, according to a multidisciplinary team of researchers.