All University of Manchester articles
-
NewsWhy killer cells can lapse into ‘exhausted’ CD8+ T cells that no longer can stem disease
In a detailed study of exhausted T cell subsets researchers show that a transcriptional repressor called Gfi1 is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.
-
NewsEarly career scientists gear up for LAM ECS Symposium next week
More than 100 delegates have now signed up for the Letters in Applied Microbiology Early Career Scientists Symposium 2025, a one-day event which is taking place in Liverpool on June 12.
-
NewsBarriers remain to peptide-based therapies - but there are answers, reveals study
Peptide-based therapies offer the potential to transform how we treat a range of conditions - but have yet to be adopted for widespread clinical use. A new review uncovers the barriers to adoption and identifies ways to overcome these limitations.
-
NewsSyringe-wielding germs could crack antimicrobial resistance crisis
Friendly germs armed with their own biological syringes and poisons could hold the key to overcoming the antimicrobial resistance crisis, according to a new study.
-
NewsBiomarker test could significantly reduce antibiotic use in sepsis
A major UK patient trial of a new biomarker testing protocol for sepsis, has shown it is possible to safely stop antibiotic treatment earlier than current care.
-
NewsGlobal review charts lethal impact of fungal infection after lung disease
An international study of chronic pulmonary aspergillosis revealed that around 32% of people who have had prior damage from lung diseases will die after five years if they also get a common fungal infection.
-
NewsIgnore antifungal resistance in fungal disease at your peril, warn top scientists
Without immediate action, humanity will potentially face further escalation in resistance to fungal disease, a renowned group of scientists from across the world has warned.
-
NewsFungus uses surface protein of its spores to weaken human immune system
An international research team discovered a special enzyme on the surface of the spores of Aspergillus fumigatus apparently suppresses the release of pro-inflammatory substances by immune cells, making it easier for the pathogen to spread in the tissue.
-
News Scientists discover superbug’s rapid path to antibiotic resistance
Researchers have discovered how a hospital superbug Clostridioides difficile (C.diff) can rapidly evolve resistance to vancomycin. In less than two months the bacteria could develop resistance to 32 times the initial antibiotic concentration.
-
NewsBiocides are a useful tool to combat antibiotic resistance but appropriate use is vital, scientists suggest
A recent review in Sustainable Microbiology discusses how the use of biocides can promote well-being but must only be used when there are clear benefits.
-
NewsOrchids support seedlings through ‘parental nurture’ via shared underground fungal networks
Early stage orchid seedlings germinate and thrive near to adult plants due to a kind of parental nurture using underground fungal networks, a new study has found.
-
NewsMicrobes linked to oilfield reservoir souring prove remarkably persistent
New research being presented at the Letters in Applied Microbiology ECS Research Symposium shines a fresh light on the persistence of microbial communities that are linked to the contamination of oilfield reservoirs - a problem that costs the energy sector billions of dollars a year.
-
NewsBiofilms play key role in reducing sensitivity to ionic silver in wound pathogens.
Bacterial pathogens in wounds that have been treated with ionic silver can adapt and become less sensitive - thanks to biofilm formation.
-
NewsClimate change disrupts vital ecosystems in the Alps
Reduced snow cover and shifting vegetation patterns in the Alps, both driven by climate change, are having major combined impacts on biodiversity and functioning of ecosystems in the high mountains, according to new research published today.
-
NewsMathematicians use AI to identify emerging COVID-19 variants
Scientists have developed an AI framework that can identify and track new and concerning COVID-19 variants and could help with other infections in the future.
-
NewsScientists develop new biocontainment method for industrial organisms
Researchers have found that by adding an estradiol-controlled destabilising domain degron (ERdd) to the genetic makeup of baker’s yeast, they can control survival of the organism.
-
NewsNew estimate doubles likely deaths from fungal disease globally
The annual total of deaths from fungal disease worldwide has risen to 3.75 million, double the previous estimate, according to a new study.
-
NewsCrop spray could lead to mass resistance in new-generation antifungal treatments
An agricultural fungicide approved in the US and currently under consideration by authorities worldwide could have a devastating effect on a new drug for one of world’s deadliest infectious diseases.
-
NewsPatients can pause immune-suppressing medicines for COVID-19 booster vaccine
A major clinical trial shows that people with inflammatory conditions are able to improve the antibody response from a COVID-19 booster vaccination by interrupting their treatment for two weeks immediately after having the vaccine.
-
NewsNew study considers risks of colistin and carbapenem resistance posed by aquatic farms
Aquatic farms could serve as a potential reservoir of colistin and carbapenem resistance, a new study warns. The review, by researchers at the University of Manchester, ‘An Update on the Prevalence of Colistin and Carbapenem-Resistant Gram-Negative Bacteria in Aquaculture: an Emerging Threat to Public Health’, has been accepted by the ...