All University of São Paulo articles
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Fungus uses surface protein of its spores to weaken human immune system
An international research team discovered a special enzyme on the surface of the spores of Aspergillus fumigatus apparently suppresses the release of pro-inflammatory substances by immune cells, making it easier for the pathogen to spread in the tissue.
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Meet the Global Ambassadors: Our Q&A with Sergio L Alves jr
The Microbiologist chats with our new Global Ambassador for Brazil, Sergio L Alves jr, Associate Professor at the Federal University of Fronteira Sul (UFFS).
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Severe COVID-19 can involve either exacerbated lung inflammation or high viral replication
Researchers report a study based on autopsies of 47 patients who died after being infected by the ancestral strain of SARS-CoV-2. The findings will support clinical decisions on the treatment of critical cases.
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Mild COVID-19 can cause long-term cognitive losses
Although the damage caused by SARS-CoV-2 was most intense among those who had severe COVID-19, some had memory loss and attention deficit more than 18 months after being infected, even though they had not needed to be hospitalized.
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Mayaro and chikungunya viruses observed circulating at the same time in the Brazilian Amazon
Infection by one virus was expected to afford protection against the other, preventing co-circulation. Researchers are warning of the risk of transmission of Mayaro in urban areas due to deforestation and advocate more effective epidemiological surveillance.
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Researchers reveals why recombinant BCG induces a stronger and longer-lasting response
Researchers are working on a more potent version of the BCG vaccine that protects against TB. While the conventional immunizer reduced infection by 90% in experiments with mice, the recombinant BCG increased protection rates to 99%.
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Scientists develop functional bread using probiotic yeast to help prevent asthma
Bread produced with probiotic yeast performed well in experiments with mice, showing potential to combat asthma, which affects 20 million Brazilians.
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Virus that causes COVID-19 can remain in sperm for 110 days after infection
Researchers detected SARS-CoV-2 in male reproductive cells under the microscope even when PCR testing failed to detect the virus in semen. The discovery serves as a warning of possible implications for natural conception and assisted reproduction.
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Researchers conduct first-ever study to characterize microbiota in saliva of weaned piglets on commercial farms in Brazil
The results show that oral fluid bacteria differ from fecal and environmental bacteria. Identification of these microorganisms can help diagnose infectious diseases and improve pork production.
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Analysis of flour and rice in Brazil shows high levels of harmful fungal toxins
The foods, found in the homes of Brazilian families participating in the research, were stored for future consumption. The study is the first in Brazil to use biomarkers to characterize the risk associated with mycotoxins in the diet.
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Study confirms effectiveness of bivalent COVID-19 vaccine
A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a new study.
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DNA vaccine against zika performs well in tests on mice
A Zika vaccine developed in Brazil and tested on mice has been found to be efficacious, inducing an immune response against the virus and protecting the animals appropriately.
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Arboviruses, mosquitoes and potential hosts tracked in real time
The technology used to sequence the first infections by SARS-CoV-2 at record speed has been successfully tested as a technique to monitor viruses transmitted by mosquitoes, such as dengue, zika, chikungunya and yellow fever.
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Study describes strategy for inactivation of multidrug-resistant bacteria
Zinc oxide nanoparticles with varying morphologies were tested against microorganisms isolated from patients.
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Study maps main genes involved in immune response to infection by dengue virus
Researchers compared data for the immune response induced by natural infection and vaccines. They identified the key factors in the development of long-lasting immunity.
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Study reveals how the chikungunya virus deploys multiple organ attack and leads to death
An international team including virologists, physicians, epidemiologists, clinicians, physicists and statisticians has discovered new mechanisms related to central nervous system infection in fatal cases of the infection
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Rare case of opossum infected by rabies sounds alarm for urban environments
The opossum was found dead in a park in the center of Campinas, a large city in São Paulo state (Brazil), with the same viral variant as fruit-eating bats. These mammals are regularly detected in cities, where they are often attacked by dogs.
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Cases of chikungunya and zika fall in Brazil, but most risk clusters rise
Researchers observed spatial and temporal patterns of occurrence and co-occurrence for the two arboviral diseases in all Brazilian municipalities, alongside the influence of environmental and socio-economic factors.
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Scientists unlock the secrets of disease-causing fungus Aspergillus fumigatus
A new study demonstrates the pivotal role of the Mitogen-Activated Protein kinase MpkA in both gliotoxin production and self-protection.
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Researchers report detailed analysis of heart injury caused by yellow fever virus
The study is the first-ever demonstration of the anatomical substrate for the cardiac arrhythmias that occur in human yellow fever.