All USA & Canada articles – Page 47
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NewsImmune ‘dysregulation’ present prior to infection predicts severe responses
A study shows that a common gene signature of immune health or dysfunction predicts severe outcomes from infection, and is present in people with known risk factors such as being a smoker or having a high body mass index, even before they encounter a pathogen.
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NewsResearchers examine the impact of mycoestrogen exposure on birth outcomes
Exposure to mycotoxins – a broad group of harmful substances produced by mold – during pregnancy may impact placental function, which could result in lower birthweight in humans.
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NewsDepression linked to a less diverse oral microbiome
A study found that people with less diversity in their oral microbiomes were more likely to have symptoms of depression. Smoking, drinking, and dental care also influenced the relationship between the oral microbiome and depression.
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NewsMachine learning method helps bring diagnostic testing out of the lab
A new point-of-care biosensing method, dubbed LOCA-PRAM, improves the accessibility of biomarker detection by eliminating the need for technical experts to perform the image analysis.
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NewsPaper-based devices diagnose malaria in asymptomatic people
Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.
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NewsScientists team up to identify infectious diseases using AI and hyperspectral imaging
A collaboration will expand patented technology to detect viral signatures in animals. ESS Protect – Animal will offer rapid, non-invasive, and contactless screening for bovine respiratory disease (BRD) using hyperspectral imaging and advanced machine learning.
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NewsImmune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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NewsLaunch of first-in-human clinical trial of next-generation rotavirus vaccine delivered via dissolvable microarray technology
Scientists have announced the first clinical trial of a novel rotavirus vaccine, CC24, delivered via dissolvable microarray technology, is now enrolling participants.
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NewsStudy highlights role of jaundice-associated pigment in protecting against malaria
New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.
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NewsBroad-spectrum coronavirus drug developed through AI-enabled dynamic modeling
Multidisciplinary AI- and physics-driven modeling of the viral fusion process enables discovery of an orally available drug inhibiting infection with multiple coronaviruses.
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NewsResearchers discover protein necessary for SARS-CoV-2 to evade the body’s defenses
Researchers have identified a protein that plays a key role in helping SARS-CoV-2 hide from the body’s defenses by suppressing the production of viral double-stranded (dsRNA), leading to increased viral replication while limiting the body’s immune response.
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NewsEvolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.
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NewsMicrobiome stability shapes how corals withstand extreme heat
A new study reveals why some corals resist bleaching while others don’t: the answer lies in a complex partnership between corals and their microbial allies, shaped by the history of the waters they inhabit.
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NewsScientists develop a treatment platform to disable the ‘biofilm’ shield of superbugs
Researchers have developed a platform that utilizes microbubbles to deliver gene-targeted nanoparticles capable of breaking down MRSA biofilms, offering an innovative solution for treating infections resistant to conventional antibiotics.
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NewsVaccinated patients hospitalized with COVID-linked acute kidney injury less likely to need dialysis after discharge
Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests. The study found vaccinated patients were less likely to stay on dialysis after discharge, and more likely to survive, than unvaccinated patients.
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NewsWhen bacteria get hungry, they kill – and eat – their neighbors
Scientists have discovered a gruesome microbial survival strategy: when food is scarce, some bacteria kill and consume their neighbors. The researchers show that under nutrient-limited conditions, bacteria use a specialized weapon — the Type VI Secretion System (T6SS) — to attack, kill, and slowly absorb nutrients from other bacterial cells.
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NewsIs your gut microbiome a calorie ‘super harvester’?
A little-known microbe makes methane in your gut — and may help you get more calories from food, according to a new study. Researchers found that people whose gut microbiomes produce a lot of methane are especially good at unlocking extra energy from a high-fiber diet.
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NewsStudy indicates that severe forms of COVID-19 infection in children may increase cardiovascular disease risks
Scientists analysed blood samples from 147 children across different COVID-19 conditions and identified significant metabolic disruptions beyond the acute viral infection phase. These alterations affect how the body processes fats (triglycerides and cholesterol) critical to healthy heart structure.
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NewsHPV drives tumor development in rare nasal cancers
Human papillomavirus (HPV) can drive tumor development in some rare sinonasal squamous cell carcinomas (SNSCCs), according to a new comprehensive study of these tumors from investigators who also identified common mutations among these cancers and a potential combination treatment.
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NewsNew research reveals a deadly fungal pathogen’s vulnerabilities
Scientists have disovered how the lethal pathogenic fungus, Cryptococcus neoformans, thrives, allowing them to identify potential novel therapeutic targets for treatment.