All USA & Canada articles – Page 67
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Streams connected to groundwater show improved detoxification and microbial diversity
Streams with ample connections to shallow groundwater flowpaths have greater microbial diversity and are more effective at preventing toxic forms of metals—often products of upstream mining—from entering and being transported downstream.
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Mice study suggests metabolic diseases may be driven by gut microbiome, loss of ovarian hormones
The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent study.
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Copies of antibiotic resistance genes greatly elevated in humans and livestock
Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. The research shows bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance ...
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Complement system response to AAV vector gene therapy
Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer – activation of the complement system.
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New method detects pathogens faster and more accurately by melting DNA
A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, producing results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
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Study of usefulness of lockdowns during epidemics identifies alternate solution
Researchers found that small nonpharmaceutical interventions can tip the optimal response between very different approaches to slowing viral spread and identified an alternate approach that has previously not been recognized as effective.
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Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
A new class of antibiotics not only shows promise against a broad array of bacterial infections but can also evade the dreaded resistance that has been rendering our current generation of first-line antibiotics ineffective.
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Long-acting HIV treatment demonstrates efficacy in people with challenges taking daily medicine as prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen, according to interim data from a randomized trial. Source: NIAID Colorized transmission electron micrograph ...
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Scientists win $434k grant to induce microbes to desert their protective biofilm
Researchers are pursuing biofilm dispersal agents such as specific enzymes in hopes the enzymes can induce microbes to leave the safety of the protective biofilm and become more susceptible to antibiotics.
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Uptake of HIV prevention medication doubles with mix of digital health interventions
A combination of interventions of one-on-one telehealth coaching, peer support forums, and automated text messages more than doubled the use of the HIV prevention strategy, called PrEP, among younger, at-risk Americans.
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Bat mating swarms may be the key to solving the next pandemic
The evolution of viral tolerance in Myotis bats may help scientists prevent future pandemics, say researchers.
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Fatty acid produced by gut bacteria directly influences fat metabolism in animals
Researchers investigating gut bacteria that produce fatty acids with a special chemical structure, known as a cyclopropane ring, showed that these can be converted into signals that turn on fat desaturation in the nematode C. elegans.
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Fungi that live in healthy plants are sensitive to climate change
Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.
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Microbiome studies explore why more women develop Alzheimer’s disease
Two new studies from the University of Chicago investigate the roles of the gut microbiome and estrogen in the differing rates of Alzheimer’s disease among women and men.
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Researchers ID decline in microbial genetic richness in the western Arctic Ocean
Small but statistically significant results point to the need for future study, say David Walsh and Arthi Ramachandran.
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Scientists engineer a coating for disease-free produce
A new wax coating technology bolsters the safety of fresh produce and provides enhanced protection against bacteria and fungi. This composite coating provides both immediate and delayed antibacterial effects, according to the article.
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Researchers are using RNA in a new approach to fight HIV
Scientists have developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
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Studies find flu vaccines were effective in 2022-2023 flu season
Two recent studies have found that flu vaccines were effective for all ages against both moderate and severe flu in the U.S. during the 2022-2023 flu season.
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Researchers discover that blocking an essential nutrient inhibits malaria parasite growth
Researchers have found that by preventing the malaria parasite from scavenging fatty acids, a type of required nutrient, it can no longer grow.
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Study shows rapid antigen COVID-19 tests done at home are reliable
Researchers report that a rapid antigen test (RAT) for detecting SARS-CoV-2, the virus that causes COVID-19, can be used at home with accuracy comparable to the same test being administered by a health care professional.