All Acinetobacter baumannii articles
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NewsResearchers discover first PLP-dependent enzyme that influences bacterial protein production
Researchers discovered aminovaleramididine synthetase (AvaS), the first pyridoxal phosphate (PLP)-dependent enzyme involved in tRNA modification, expanding scientific understanding of how RNA shapes the reading of genetic information. The discovery reveals a previously unknown mechanism that bacteria use to regulate protein production.
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NewsThe fast track to antibiotic resistance
Researchers uncover a hidden mechanism that enables bacteria to rapidly develop antibiotic resistance; disrupting this mechanism could improve the effectiveness of antibiotic treatments.
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NewsLast-line antibiotics at risk as children’s resistance rises
Antimicrobial resistance in children is rising globally and will worsen over the next decade, threatening the effectiveness of life‑saving antibiotics, according to a world-first monitoring platform.
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NewsFrom infancy to old age, nationwide China study maps how serious lung infections change across life stages
An analysis of 695,142 hospitalized patients identifies eight life-stage pathogen profiles, three co-detection networks, and marked male predominance in bacterial and fungal infections.
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NewsQuiet emergence of superbug threat revealed in new study
Decades-old hospital samples have helped researchers uncover how a deadly antibiotic-resistant “superbug” quietly tightened its grip across the globe.
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NewsAI reveals unexpected source of antibiotic candidates in prion proteins
Prion and prion-like proteins may hide short peptides, named “prionins,” that can kill bacteria, suggesting proteins best known for their role in neurodegeneration may contain molecular features linked to immune defense, according to new research.
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NewsWhy babies are dying and how we can stop it
A study has identified that the vast majority of neonatal deaths caused by infections in South Africa and other low-and-middle-income countries could be prevented through improved clinical care and targeted medical interventions.
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NewsGut microbiota impacts resistance to bacterial pneumonia: Study
A gut-lung connection influences susceptibility to infection by Acinetobacter baumannii, according to a new study. Investigators found that antibiotics disrupt the gut microbiota, suppress protective immune system pathways in the lungs; and increase the severity of pneumonia.
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NewsCharacteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
A new study investigates the relationship between reduced CD4+T-cell counts and lung infections in immunosuppressed patients admitted to intensive care units (ICUs).
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NewsHoly Grail: One vaccine may provide broad protection against many respiratory infections and allergens
In a new study in mice, researchers have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and even allergens.
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NewsSugar molecules point to a new weapon against drug-resistant bacteria
Researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognise a sugar found only on bacterial cells – an advance that could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections.
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NewsPositive signs in the fight against superbugs: CHINET 2024 surveillance report
The 2024 CHINET antimicrobial resistance surveillance report uncovers a hopeful trend in China’s battle against bacterial resistance, with a significant reduction in resistance among several key pathogens.
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NewsPlant extracts show promise in reducing human pathogen risks in agricultural soils
A new study has revealed that natural plant extracts can significantly lower the risks posed by human bacterial pathogens in manure amended agricultural soils. The eco friendly strategy disrupts the communication systems that bacteria use to coordinate harmful activities.
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NewsEvolving antibiotic resistance under pressure may lead to personalized treatment
A new study demonstrates the use of an experimental evolution approach to map genetic mutations in Acinetobacter baumannii treated with one of two uncommon antibiotics.
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NewsResearchers discover novel phage DNA modifications that offer new hope against antibiotic-resistant superbugs
A groundbreaking discovery reveals a unique way phages modify their DNA with arabinose sugars to protect themselves from bacterial defence systems. Natural DNA phage modifications occur at a higher rate than previously predicted, the study revealed.
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NewsGlobal action urgently needed to tackle antimicrobial resistance, experts warn
Scientists have called for urgent changes to the way new antibiotics are developed to address the growing problem of antimicrobial resistance (AMR). They outline the scientific, economic, and regulatory barriers that are slowing progress.
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NewsGifts from the sea: Molecules derived from coral may help fight harmful bacteria
Pus, strep throat, and even tuberculosis—most infectious diseases are characterized by a cluster of pathogenic bacteria that can be stubborn and resistant to antibiotics. Researchers have found another method to combat these bacteria using naturally sourced molecules found in corals.
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NewsA repurposed FDA-approved drug shows promise in killing antibiotic resistant bacteria
A study of Acinetobacter baumannii employed an entirely new strategy to identify weaknesses specific to resistant bacteria and then target these weaknesses with an alternate drug. They found that fendiline kills the bacterium by targeting the essential lipoprotein trafficking pathway, which is weakened in antibiotic resistant bacteria.
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NewsNew source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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NewsSpiritual healing sites could be linked to antibiotic-producing microorganisms
A study by AMI member Dr Gerry Quinn highlights the potential of spiritual healing sites as fertile ground for novel antibiotics, particularly from Streptomyces bacteria, known for producing the majority of current antibiotics.