All Amsterdam UMC articles
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NewsTemporary benefit for immune system in early HIV treatment, but dysregulation returns
A study investigated whether immune dysregulation can be prevented by starting HIV medication immediately after infection. Six months after this early treatment, the immune system did indeed work as in people without HIV, but in the longer term, the immune system was disrupted again.
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NewsNIH grant aims for childhood vaccine against HIV
A multi-institutional team led by Weill Cornell Medicine investigators has been awarded a five-year, $20.8 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, for advanced preclinical development of a promising experimental HIV vaccine. Source: NIAID Transmission electron micrograph ...
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NewsProof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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NewsDietary shift after migration increases cardiovascular risk by altering the gut microbiome
An Amsterdam UMC-led study has found that migrants, this case from West Africa to Europe, experience a ‘clear change’ in their microbiome composition as compared to their non-migrant peers in West Africa, which expose them to an increase of cardiovascular disease. These peer-reviewed findings are published in ...
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NewsResearchers identify critical immune factor for host defense against MRSA
Researchers identify a critical immune factor for host defense against MRSA, offering a potential explanation for failures of previous vaccine strategies and a proposal for a new direction for tackling this bacterium.
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NewsFewer good gut bacteria increase the risk of serious infection
Researchers followed more than 10,000 people for 6 years. More than 600 people who had less healthy intestinal flora developed a serious infection, with this leading in some cases to death.
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NewsStudying alcohol production in the intestines of overweight patients
Researchers undertaking a major study into the underlying causes of excessive alcohol production in the gut hope to find a way to prevent excess alcohol produced in the intestines, and thus the related diseases.
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NewsHIV in cell culture can be completely eliminated using CRISPR-Cas gene editing technology
New research demonstrates transport of new-gene editing technology to ‘cut out’ HIV DNA from infected cells; preliminary findings are “very encouraging”, but much work is needed to transform the technology into a cure for HIV.
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NewsTuberculosis bacteria present in 90% of those with symptoms - including those who test negative
Mycobacterium tuberculosis (Mtb) is present in exhaled breath of 90% of those presenting with suspected tuberculosis. This includes those who were negative on conventional sputum testing and not diagnosed with TB.
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NewsConsortium to tackle the effect of climate change on diarrheal diseases
Thanks to a Horizon Europe grant, Amsterdam UMC together with the Amsterdam Institute for Global Health and Development, is set to lead a global consortium to improve policies and interventions
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NewsNew study shows link between make-up of microbiome and depression
Research by Amsterdam UMC, the University of Amsterdam and Erasmus MC has delivered the most extensive evidence to date of a relationship between the composition of the microbiome and instances of depression.