All Amsterdam UMC articles
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NewsNIH grant aims for childhood vaccine against HIV
A multi-institutional team led by Weill Cornell Medicine investigators has been awarded a five-year, $20.8 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, for advanced preclinical development of a promising experimental HIV vaccine. Source: NIAID Transmission electron micrograph ...
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NewsProof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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NewsDietary shift after migration increases cardiovascular risk by altering the gut microbiome
An Amsterdam UMC-led study has found that migrants, this case from West Africa to Europe, experience a ‘clear change’ in their microbiome composition as compared to their non-migrant peers in West Africa, which expose them to an increase of cardiovascular disease. These peer-reviewed findings are published in ...
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NewsResearchers identify critical immune factor for host defense against MRSA
Researchers identify a critical immune factor for host defense against MRSA, offering a potential explanation for failures of previous vaccine strategies and a proposal for a new direction for tackling this bacterium.
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NewsFewer good gut bacteria increase the risk of serious infection
Researchers followed more than 10,000 people for 6 years. More than 600 people who had less healthy intestinal flora developed a serious infection, with this leading in some cases to death.
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NewsStudying alcohol production in the intestines of overweight patients
Researchers undertaking a major study into the underlying causes of excessive alcohol production in the gut hope to find a way to prevent excess alcohol produced in the intestines, and thus the related diseases.
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NewsHIV in cell culture can be completely eliminated using CRISPR-Cas gene editing technology
New research demonstrates transport of new-gene editing technology to ‘cut out’ HIV DNA from infected cells; preliminary findings are “very encouraging”, but much work is needed to transform the technology into a cure for HIV.
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NewsTuberculosis bacteria present in 90% of those with symptoms - including those who test negative
Mycobacterium tuberculosis (Mtb) is present in exhaled breath of 90% of those presenting with suspected tuberculosis. This includes those who were negative on conventional sputum testing and not diagnosed with TB.
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NewsConsortium to tackle the effect of climate change on diarrheal diseases
Thanks to a Horizon Europe grant, Amsterdam UMC together with the Amsterdam Institute for Global Health and Development, is set to lead a global consortium to improve policies and interventions
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NewsNew study shows link between make-up of microbiome and depression
Research by Amsterdam UMC, the University of Amsterdam and Erasmus MC has delivered the most extensive evidence to date of a relationship between the composition of the microbiome and instances of depression.