All azoles articles
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News
Research points the way to lifesaving antiparasitic drugs while unlocking a scientific mystery
A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that kills about 30,000 people around the world every year.
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Deadly mould strains highly likely to acquire resistance to new drugs
Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most effective antifungal drugs, which are also five times more likely to acquire resistance to desperately needed new treatments in development. Source: Ufficio Comunicazione, Azienda Ospedaliera SS. Antonio e ...
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Policy change may be helping to drive rise in treatment-resistant vaginal thrush
A change in policy may be helping to drive a rise in treatment-resistant vaginal thrush, amid significant yearly increases in the prevalence of fungal infections caused by fungal Candida species, suggests the first study of its kind.
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Bone loss drugs can help azoles fight fungal infections
A new study suggests that adding common bone loss drugs to azoles can improve efficacy. In lab tests, combinations of these drugs worked against dermatophyte species and prevented resistance.
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Crop spray could lead to mass resistance in new-generation antifungal treatments
An agricultural fungicide approved in the US and currently under consideration by authorities worldwide could have a devastating effect on a new drug for one of world’s deadliest infectious diseases.
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Statins team up with azoles to battle fungal infections
Researchers evaluated the antifungal efficacy of the pitavastatin-azole combination in silkworm models, suggesting its potential as an effective clinical treatment.
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New vaccine targets life-threatening fungal infections
A new vaccine from the University of Georgia could be the first clinically approved immunization to protect against invasive fungal infections, a growing concern as antifungal drug resistance increases.