All biomarkers articles
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NewsGut microbiome emerges as a potential partner in precision cancer therapy
A new editorial examines how the human microbiome may influence cancer development, treatment response and emerging precision-oncology strategies.
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NewsRoot gene panel reveals hidden apple replant disease
In-depth research is needed to identify biomarkers that can diagnose apple replant disease (ARD) consistently across diverse soils. Researchers measured the expression of 90 candidate genes in the roots of ARD-sensitive ‘M.26’ apple plants grown in soils from 151 German sites.
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NewsResearchers discover how Epstein-Barr Virus triggers multiple sclerosis attacks
In a study of blood samples from more than 100 participants with MS, researchers detected increased EBV lytic activity in immune cells up to three months before MS relapse and discovered that these cells also showed elevated expression of genes linked to MS risk.
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NewsGut, airway and tumor microbes emerge as promising predictors of immunotherapy response in lung cancer
A comprehensive review systematically evaluates the microbiome’s role in lung cancer immunotherapy. Authors synthesized evidence covering microbial communities in the oral cavity, airways, lung tumors and gut, and their connections to treatment efficacy and immune‑related adverse events.
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NewsIntratumoral Fusobacterium as a prognostic and predictive biomarker in resectable colorectal cancer
Research supports the use of Fusobacterium as a prognostic and predictive biomarker in patients with resectable stage I–III CRC. Its presence was associated with more aggressive disease, a weaker immune response, and limited benefit from adjuvant chemotherapy.
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NewsThe respiratory microbiota in lung cancer: from dysbiosis and immunomodulatory networks to therapeutic opportunities
A comprehensive review reveals that dysbiosis of the respiratory microbiota drives lung cancer through four integrated pathways: oncogenic signaling, epigenetic/metabolic reprogramming, and chronic immune dysregulation.
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NewsNew fluorescent nanosensor enables first-of-its-kind detection of key gut health biomarker
Researchers have developed a novel fluorescent nanosensor capable of rapidly detecting indole-3-propionic acid (IPA), an emerging biomarker linked to gut health and disease. The sensor produces a rapid optical readout within minutes, offering a significantly faster and more accessible alternative to conventional analytical techniques.
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NewsIntestinal Candida albicans is associated with subclinical coronary atherosclerosis in metabolic dysfunction-associated steatotic liver disease with cirrhosis
Researchers have published the first report of gut fungal dysbiosis associated with the severity of metabolic dysfunction-associated steatotic liver disease and subclinical coronary atherosclerosis. An increased abundance of fecal C. albicans was observed in patients with cirrhosis and high SCA burden.
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NewsExtracellular vesicle RNAs offer new hope for diagnosing and treating chronic inflammatory bowel disease
Extracellular vesicle-associated RNAs can serve as non-invasive biomarkers for early inflammatory bowel disease detection and disease monitoring, and also hold great potential as targets for next-generation targeted therapies, according to a new review.
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NewsBlood test using artificial intelligence paves the way for early diagnosis of leprosy
A new blood test combined with a standardized questionnaire and artificial intelligence may transform the way leprosy is diagnosed in Brazil. The method showed potential for identifying the disease in its initial stages, when symptoms are subtle and traditional laboratory tests often fail.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
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NewsNew algorithm enhances microbiome biomarker discovery by integrating biological relationships
Researchers have developed a novel algorithm, Microbiome Elastic Feature Extraction (MEFE), that significantly improves the identification of microbiome biomarkers by incorporating phylogenetic, taxonomic, and functional relationships among microbes.
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NewsCARB-X to support development of typhoid fever diagnostic from Chembio
CARB-X is awarding US$1.8 million to Chembio Diagnostic Systems, Inc. to develop a rapid point-of-care test for the detection of Immunoglobulin A (IgA) antibodies to diagnose acute infection of Salmonella enterica serovar Typhi.
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NewsWho is more likely to get long COVID?
Scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
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NewsStudy unravels the fungi-cancer connection
A growing body of evidence indicates that the microbiome within the gut and tumors significantly influences cancer initiation, progression, and treatment response. Current research primarily focuses on bacteria, whilst the role of fungi is only now gaining attention.
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NewsMucosal virome and host transcriptome interactions reveal viral influence in colorectal polyp development
A new study has provided the first integrated mucosal virome-transcriptome landscape of colorectal polyps, the precursors of colorectal cancer, offering new insights into viral-host interactions at this early disease stage.
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NewsCuring hepatitis C can rebalance immunity in Indonesians living with HIV
A new study provides the first longitudinal immunological data on HIV/HCV-coinfected individuals in Southeast Asia, underscoring the importance of early hepatitis C treatment to prevent long-term immune and liver complications.
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NewsGut microbiome connects obesity to cancer, impacting public health
A new review highlights growing scientific evidence that imbalances in gut bacteria can influence metabolism, trigger inflammation, and increase cancer risk. These insights offer new possibilities for disease prevention, early detection, and personalized health care.
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NewsGut microbiota: implications in pathogenesis and potential therapeutic target in primary biliary cholangitis
A new review synthesizes current evidence on gut microbiota dysbiosis in PBC, elucidates its pathogenic mechanisms, and explores its potential as both a diagnostic biomarker and a novel therapeutic target.
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NewsAccessible imaging technique can predict cardiac risks in patients with Chagas disease
A simple imaging exam capable of assessing myocardial deformation during contraction has emerged as a promising tool for predicting the risk of cardiac complications in patients with chronic Chagas disease.