All chemotherapy articles
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NewsIntratumoral Fusobacterium as a prognostic and predictive biomarker in resectable colorectal cancer
Research supports the use of Fusobacterium as a prognostic and predictive biomarker in patients with resectable stage I–III CRC. Its presence was associated with more aggressive disease, a weaker immune response, and limited benefit from adjuvant chemotherapy.
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NewsReshaping the gut microbiome can boost chemotherapy delivery to tumors
A common antibiotic reshaped gut bacteria in preclinical models, significantly reducing liver clearance and doubling how long chemotherapy remained in circulation to reach tumors.
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NewsStudy identifies serious infection risks linked to targeted cancer therapies
A major real-world study has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Some ADCs were associated with substantial rates of severe neutropenia – dangerously low levels of infection-fighting white blood cells – and related complications.
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NewsSleep deprivation disrupts gut microbiota, worsening colorectal cancer outcomes
Researchers have found that the gut microbiota drives changes to the immune system caused by chronic sleep loss. These changes promote cancer progression, disrupt circadian rhythm and weaken the effectiveness of chemotherapy.
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NewsMore investigations needed into Wumei Pills-Lactobacillus Reuteri-intestinal stem cell axis for chemotherapy-Induced mucositis
A new letter appraising a recent study suggests the reported benefits of WMP and Lactobacillus reuteri in chemotherapy-induced mucositis are promising, but stronger causal and analytical foundations are needed.
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NewsChemotherapy rewires gut bacteria to curb metastasis
Researchers report that chemotherapy-induced damage to the intestinal lining alters nutrient availability for gut bacteria, reshaping the microbiota and increasing the production of indole-3-propionic acid (IPA), a tryptophan-derived microbial metabolite.
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NewsResearchers see dramatic drop in HIV-infected immune cells in patient after cancer treatment received
Researchers report they may have taken an early step toward a more practical HIV cure. They focused on a patient undergoing cancer treatment and also living with HIV, who after receiving chemotherapy, had a significant reduction in the number of CD4+ T immune cells that contained an HIV provirus.
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NewsMicrobial allies: Bacteria help fight against cancer
An international team of scientists have discovered that microbes associated with tumours produce a molecule that can control cancer progression and boost the effectiveness of chemotherapy.
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NewsCan gut microbes save patients from chemotherapy side effects?
Intestinal microbes that survive chemo can rid the gut of excess chemo drugs and produce a vitamin that helps to stem nausea, a new study reveals.
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NewsBiosynthetic pathway discoveries mean we can halve the price of costly cancer drug
Researchers have identified the enzymes responsible for the two critical final steps in the biosynthetic pathway that makes the chemotherapy drug Taxol active as a drug, potentially opening it up to biotech based production.
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NewsProbiotic supplementation may help reduce chemotherapy side effects in breast cancer
A new study shows that probiotics with seven strains have a potential effect in patients with breast cancer, especially in the improvement of common chemotherapy-related side effects such as fatigue and nausea.
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NewsHepatitis B is a problem for a growing number of patients on immunosuppressive medications
The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.
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NewsChemotherapy disrupts gut microbiome in patients with breast cancer
Patients treated with chemotherapy who showed decreases in cognitive performance also had reductions in the diversity of their gut microbiome, a new study has found.