All Clostridioides difficile articles
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CareersA conversation at the forefront of human microbiome research
Yang Yue and Professor Alan Walker discuss everything from precision medicine and the omics approach, to challenges in the road ahead and the future of microbiome research.
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NewsDiagnostic stewardship approach to C. diff reduces unnecessary testing
Revised rules for when Clostridioides difficile tests could be ordered helped to reduce inappropriate testing by 20%, which in turn can help rein in the overtreatment of patients.
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NewsNew antibiotic kills pathogenic bacteria, but spares healthy gut microbes
Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.
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NewsViolin resin effective against deadly pathogens - even in dirty conditions
A form of resin used to treat violin strings could double as an effective disinfectant against some of the world’s most deadly diseases, a new study shows.
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NewsNew weapon against the super tough C diff bacteria shows promise
A researcher has demonstrated that a newer generation tetracycline antibiotic, Omadacycline, may be a promising tool in combating the resilient bacteria Clostridioides difficile (C diff), which causes an infection often picked up in hospitals.
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NewsChlorine disinfectant is no more effective than water at killing off hospital superbug
Research explores the impact of using recommended chlorine chemicals to tackle Clostridioides difficile, the most common cause of antibiotic associated sickness in healthcare settings globally.
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NewsNovel C. diff structures are required for infection and offer new therapeutic targets
Iron storage ‘spheres’ inside the bacterium C. diff — the leading cause of hospital-acquired infections — could offer new targets for antibacterial drugs to combat the pathogen.
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NewsResearcher awarded $1.9m to develop model to test phages in the gut
Bryan Hsu, an assistant professor of biological sciences at Virginia Tech, has received a five-year $1.9 million award to develop a model to test the role of lytic bacteriophages, or phages as they are commonly called, in the mammalian gut.
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CareersThe lure of microbes: Getting to know some of the new junior editors at Letters in Applied Microbiology
Applied Microbiology International has just appointed 14 junior editors to its flagship journal Letters in Applied Microbiology (LAM) - so we got to know some of the new crew.
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NewsAcademic-private partnership aims to reduce toxic effects of deadly C. diff
The Center for One Health Research and Nectagen Inc. have received a nearly $275,000 grant to study whether synthetic proteins developed by Nectagen can reduce the toxicity of the digestive bacterium.
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News‘Hospital pathogen’ widespread in Vietnam’s environment
A pathogen considered to be a cause of hospital infection is widespread in Vietnam, turning up in farm soil and pig faeces as well as hospital beds and toilet floor surfaces, with 70% of isolates found to be resistant to at least one class of antimicrobials.
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NewsInter-species interactions may stymie antibiotics
A new study suggests that between-species interactions within the gut microbiome may impact the efficacy of antibiotics aimed at treating C. difficile infections.
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NewsSensor controls how dormant bacteria reawaken
Researchers have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.
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NewsStool transplants more effective than antibiotics for treating recurring, life-threatening gut infections
A new Cochrane Review has found that, compared with standard antibiotic treatment, stool transplantation can increase the number of people recovering from Clostridioides difficile infection from 40% to 77%.
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NewsCocktail of bile salt hydrolases can stop C diff in its tracks
Researchers have found that bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut’s microbial environment.
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NewsAntibiotic resistant microbes in gut make C difficile more infectious
Scientists have found that Enterococcus – an antibiotic-resistant, opportunistic pathogen – works together with Clostridioides difficile in the human gut, reshaping and enhancing the metabolic environment in the gut so that C. difficile can thrive.
