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NewsHidden toxicity unmasked: engineered E. coli sets record for hemostatic compound dencichine
Dencichine, the hemostatic active ingredient of the herb panax notoginseng is hard to obtain, with earlier engineered E coli strains low-yielding and growing poorly. Researchers have traced the growth defect to a hidden toxicity and their fix resulted in a final strain that produced the highest reported titer to date.