All Early Career Research articles – Page 2
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News
Researchers engineer a herpes virus to turn on T cells for immunotherapy
Researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival - a promising tool in the fight against cancer.
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Yeast produces human DNase1 for the first time
The protein DNase1 is used to treat cystic fibrosis but it takes considerable effort and cost to produce it in immortalized hamster cells. Researchers have now produced it in yeast cells for the first time.
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Zika virus uses cells’ ‘self-care’ system to turn against host
A new study reveals the biological secret to the Zika virus’s infectious success: Zika uses host cells’ own ‘self-care’ system of clearing away useless molecules to suppress the host proteins that the virus has employed to get into those cells in the first place.
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Yeast reveals how species adapt to a warmer climate
Researchers harnessed the power of experimental evolution with the microbial model system yeast (Saccharomyces spp.) to measure the evolutionary potential of populations to adapt to future warming, in real time and across the entire species tree.
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Cool science: Researchers craft tiny biological tools using frozen ethanol
Imagine drawing on something as delicate as a living cell — without damaging it. Researchers have made this groundbreaking discovery using an unexpected combination of tools: frozen ethanol, electron beams and purple-tinted microbes.
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Wastewater treatment to fight the spread of antibiotic resistance
A metagenomics study has demonstrated that one type of bioreactor used in some wastewater plants – anaerobic membrane bioreactors – may be better at reducing the amount of ARGs released into the environment.
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Particles carrying multiple vaccine doses could reduce the need for follow-up shots
Researchers are working to develop microparticles that can release their payload weeks or months after being injected. This could lead to vaccines that can be given just once, with several doses that would be released at different time points.
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Proof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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New study offers insights into designing safe, effective nasal vaccines
Researchers found that nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, even without the help of immune-boosting ingredients known as adjuvants. The findings, researchers suggest, may offer critical insights into developing safer, more effective nasal vaccines in the future.
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Targeted nanoparticles show promise for more effective antifungal treatments
Researchers have developed a new nanotechnology-based approach that could improve treatment of fungal infections, particularly those caused by the increasingly drug-resistant Candida species.
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Study uncovers how the plastisphere can influence growth of harmful algal blooms
A new study published in Sustainable Microbiology delves into how the age and size of microplastics affects the growth of harmful algal blooms.
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Antibiotics from human use are contaminating rivers worldwide, study shows
Millions of kilometres of rivers around the world are carrying antibiotic pollution at levels high enough to promote drug resistance and harm aquatic life, a new study warns.
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Careers
Metabolomics from Manchester to Madrid
Discover how an AMI Grant helped Breanna Dixon to further her PhD, professional development, and build an international partnership.
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Electricity-generating bacteria may power future innovations
Scientists have discovered how certain bacteria breathe by generating electricity, using a natural process that pushes electrons into their surroundings instead of breathing on oxygen.
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Dancing plant cells defeat Pseudomonas - and win international competition
The University of Jena, Germany has won the renowned ’Dance your PhD’ competition in the category Biology with its video “Plant Vaccination”. The video visualizes the thesis of Jena doctoral candidate Priya Reddy with dancers and original choreography.
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The solution for microbial communities to survive environmental stress is self-sufficiency
Researchers have shown, based on an experimental system that reproduces a mutualistic microbial community, that the most common evolutionary solution for two co-dependent organisms to survive extreme environmental change could be to become self-sufficient.
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AI plays detective to help scientists find hidden microbes
A team of researchers has created a novel machine learning tool that’s cracking open one of biology’s trickiest puzzles: finding the rarest microbes on Earth. Ulrb not only identifies rare microorganisms but also works with non-microbial data.
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New molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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Barriers remain to peptide-based therapies - but there are answers, reveals study
Peptide-based therapies offer the potential to transform how we treat a range of conditions - but have yet to be adopted for widespread clinical use. A new review uncovers the barriers to adoption and identifies ways to overcome these limitations.
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Study of facial bacteria could lead to probiotics that promote healthy skin
Researchers have revealed the dynamics of interactions between two dominant skin bacterial species in more detail than previously possible, shedding light on when and how new bacterial strains emerge on the skin of the face.