All hepatocytes articles
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NewsMetabolites produced in the intestine play a central role in controlling obesity and diabetes
A study has identified a group of metabolites that travel from the intestine to the liver and then to the heart, where they are pumped throughout the body. These metabolites play an important role in controlling metabolic pathways in the liver and insulin sensitivity.
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NewsBacterium promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals
Parabacteroides distasonis promotes liver regeneration by increasing BHB production and BHB-driven STAT3 signals, providing an argument for using P. distasonis or BHB as a potential strategy for promoting hepatic regeneration after PHx or transplantation.
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NewsScientists unveil hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression
In liver cells under oxidative stress, HBV core protein (HBc) perturbs mitochondrial dynamics and prevents cellular recycling of damaged mitochondria, thereby driving liver disease progression, a new study finds.
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NewsBacteria behind biblical disease have potential to regenerate livers
Scientists have discovered that the bacterium that causes leprosy can reprogramme cells to increase the size of a liver in adult animals without causing damage, scarring or tumours.