All immune checkpoint inhibitors articles
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NewsGenetically engineered Bifidobacterium shows potential for oral delivery of cancer vaccines
A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity. In an exploratory phase I clinical study, the vaccine was well tolerated and generated immunologic and clinical findings that warrant further investigation.
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NewsNew study links gut bacteria to immunotherapy success in melanoma patients
Researchers have identified specific gut bacteria linked to better responses to cancer immunotherapy in patients with advanced melanoma. Patients who responded well to treatment were more likely to have a specific type of gut bacteria called Faecalibacterium.
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NewsGut bacteria molecule boosts lung cancer treatment response
Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
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NewsStudy finds COVID-19 mRNA vaccine sparks immune response to fight cancer
Patients with advanced lung or skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine, researchers have found.
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NewsHPV integration: Moving from carcinogenesis mechanisms to clinical applications
The clinical significance of HPV integration into the host genome is substantial, particularly in cervical cancer screening programs. Integration testing has emerged as a valuable triage tool for detecting high-grade cervical intraepithelial neoplasia (CIN III+).
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NewsGut microbiome transplants show promise for boosting cancer immunotherapy
A comprehensive new review examines the effects of transferring healthy gut bacteria to cancer patients receiving immune checkpoint inhibitors (ICIs).
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NewsResearchers identify why cancer immunotherapy can cause colitis
Studies in mice reveal the mechanism that induces this severe side effect and point to a solution that kills the cancer without causing gastrointestinal issues.