All immunotherapy articles
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NewsFecal microbiota transplantation improves response to immunotherapy in advanced kidney cancer
A new study provides compelling evidence that fecal microbiota transplantation (FMT) can enhance the effectiveness of immunotherapy in patients with advanced metastatic renal cell carcinoma (mRCC).
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NewsGut bacteria molecule boosts lung cancer treatment response
Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
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NewsVictoria’s Secret grant backs cutting-edge ovarian cancer research
Promising ovarian cancer research by Melanie Rutkowski, PhD, at the University of Virginia Comprehensive Cancer Center has won $700,000 in support from the Victoria’s Secret Global Fund for Women’s Cancers in partnership with Pelotonia and AACR, the American Association for Cancer Research.
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NewsGut bacterium impairs liver cancer treatment, inducing immunotherapy resistance
Researchers discovered that transplanting the gut bacterium Phocaeicola vulgatus into mouse models of liver cancer induced immunotherapy resistance. The finding is consistent with clinical observations in patients, showing that patients with low levels of P. vulgatus responded better to treatment.
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NewsMERIT grant awarded to study cure for HIV
A scientific team has received an NIH MERIT Award to provide long-term grant support to study a handful of people who have managed to clear HIV after a stem cell transplant and those who did not.
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NewsWhy killer cells can lapse into ‘exhausted’ CD8+ T cells that no longer can stem disease
In a detailed study of exhausted T cell subsets researchers show that a transcriptional repressor called Gfi1 is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.
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NewsGut microbes key to understanding how exercise boosts cancer immunity
A new study shows how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome. These benefits are driven by a specific compound called formate, which is produced by gut bacteria in exercised mice.
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NewsCentauri Therapeutics selects first clinical candidate for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited has announced the selection of its first clinical candidate in the ABX-01 programme. The compound is designed to target serious Gram-negative bacterial infections in the lung.
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NewsNew evidence links gut microbiome to chronic disease outcomes
A new review consolidates recent findings that demonstrate a causal role for the gut microbiome in the progression of multiple diseases, ranging from gastrointestinal conditions to immune-related and psychiatric disorders.
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NewsCombining virus therapy with radiation to fight brain cancer works better than either treatment alone
Combining a cancer-targeting virus with radiation to treat brain cancer in mice was more effective than either therapy on its own, according to new research, providing hope for new treatments that combine immunotherapy with traditional surgery, chemotherapy or radiation.