All Infection Prevention & Control articles – Page 12
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NewsGladstone launches Center for PhAIge Therapy to harness AI in the fight against drug-resistant infections
Gladstone Institutes has received funding to establish the Center for PhAIge Therapy, a research center that will develop new phage-based treatments for antibiotic-resistant bacterial infections. The five-year grant makes Gladstone one of three institutions across the country selected to lead this coordinated effort.
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NewsT cells may be key to stopping measles virus—and its deadly relatives
Scientists have discovered how T cells target paramyxoviruses, a viral family that includes measles virus and Nipah virus. Instead of vaccinating against one virus at a time, the researchers found that activating “cross-reactive” T cells may protect against the wider paramyxovirus family.
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NewsBiomaterial made from jackfruit latex is a promising treatment for periodontitis
Researchers have developed a biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin that shows promising efficacy in treating periodontitis. This chronic inflammatory disease of infectious origin leads to the progressive destruction of the tissues supporting the teeth, resulting in bone resorption and loss of attachment.
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NewsStudy identifies serious infection risks linked to targeted cancer therapies
A major real-world study has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Some ADCs were associated with substantial rates of severe neutropenia – dangerously low levels of infection-fighting white blood cells – and related complications.
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NewsPhase 1 clinical trial set to begin on first leishmaniasis vaccine
A phase 1 clinical trial testing the safety of a leishmaniasis vaccine is set to begin in the coming months. The live vaccine, found to be safe in animals, is expected to be tested in humans later this year.
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NewsNew study identifies key warning signs for infection after ankle fracture surgery in older patients
A new study of which patients are most at risk of a fracture-related infection post ankle surgery finds that low protein levels in the blood is the single strongest patient-related risk factor, making infection nearly 18 times more likely. Chronic alcohol abuse and failure to follow post-operative instructions each raise the risk more than fivefold.
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NewsZinc deficiency promotes fluconazole-resistant Candida auris virulence
Researchers identified key nutritional and genetic factors that drive the virulence of fluconazole-resistant Candida auris. Under zinc-deficient conditions, these drug-resistant strains gain a fitness advantage, exhibiting increased pathogenicity and resistance to macrophage-mediated killing.
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NewsHow Chinese cabbage fights downy mildew
Researchers focusing on the Brassica rapa–Hyaloperonospora parasitica pathosystem identifies DM459 as an Arg–x–Leu–Arg (RXLR) effector that interacts with BraATG8i, activates autophagy, stimulates salicylic acid (SA) signaling, and enhances resistance to downy mildew.
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News‘Accidental’ discovery lays foundation for novel flu treatment strategies
Scientists investigating how influenza viruses replicate within cells “accidentally” discovered that different flu viruses use distinct strategies to infiltrate cells in the first place. They also found that it is possible to target specific molecules to prevent the viruses from entering new cells, thereby stopping their replication.
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NewsEngineered gut bacteria therapy emerges as scalable potential alternative to fecal microbiota transplants following clinical trial
Researchers have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection.
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NewsReal-time brain monitor detects infections earlier
A research team has created a new monitoring system to save lives and significantly reduce health-care costs in brain-injury cases through the early detection of infections in intensive care units. NeuroSense connects to drainage lines to detect biomarkers of infection.
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NewsPan-European One Health Network established to bolster infectious disease response
iiCON: the Infection Innovation Consortium has successfully secured funding from COST to establish a unique pan-European COST Action network with over 70 collaborators from 21 countries and international organisations to harmonise the European response to infectious disease threats.
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NewsBehind the diagnosis: How laboratory testing guided a complex histoplasmosis case
A diagnosis of histoplasmosis forced a teenager with juvenile arthritis onto an uncertain path, one defined by months of treatment, recovery, and a long-term course of antifungal therapy expected to last up to three years. Histoplasma capsulatum, a dimorphic fungus that causes histoplasmosis, found its way into her lungs.
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NewsPost-discharge antibiotics may offer limited benefit after pediatric appendicitis
Acute appendicitis is one of the most common surgical emergencies among children, and complicated acute appendicitis (CAA), including perforated or gangrenous disease, carries a higher risk of infection and longer hospitalization. While intravenous antibiotics during hospitalization are standard practice, the role of oral home antibiotics (OHA) after discharge remains controversial. ...
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NewsPrecigen presents new long-term durability data for PAPZIMEOS, recently granted seven-year market exclusivity
Precigen, Inc. has announced updated long-term follow-up data from the pivotal study of PAPZIMEOS™ (zopapogene imadenovec-drba) for the treatment of adults with recurrent respiratory papillomatosis (RRP).
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NewsNew analysis confirms benefits of childhood flu vaccines
Pediatric flu vaccines significantly reduce the number of childhood cases of influenza, new research confirms. The findings show that for every 100 children vaccinated, between nine and 14 fewer children catch the flu.
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NewsProtection for newborns: New treatment aims to prevent meningitis without antibiotics
One of the leading pathogens responsible for meningitis cases in newborn babies is the K1 form of the E. coli bacterium. Now, researchers have developed a triple-pronged approach that seeks to prevent transmission to newborns.
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NewsResearchers discover tick protein that may block disease transmission
Researchers have found that ticks produce an exosomal glycine-rich protein that plays a vital role in helping ticks feed and transmit viruses. When they used genetic tools to silence the gene responsible for this protein, ticks lacking the protein struggled to feed effectively and showed reduced body weight after feeding.
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NewsHealth researchers call for support to develop pandemic prevention
The Vanderbilt Center for Antibody Therapeutics has received large-scale government grants and contracts to fund the discovery of human antiviral antibodies. The problem is the next step — finding corporate partners to develop the antibodies through human testing.
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NewsRecent study reveals how bacteria capture a rare type of sugar molecule
Researchers have identified a novel transport protein that binds cyclic β-1,2-glucans, revealing unexpected diversity in bacterial sugar uptake mechanisms.