All Infection Prevention & Control articles – Page 13
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NewsNovel therapeutic drug for tuberculosis is proposed using high-precision molecular simulation
Researchers have proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques. The proposed drug is anticipated to bind strongly to the drug-metabolizing enzyme cytochrome P450 (CYP).
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NewsNew antibiotic design could help treat drug-resistant infections
A new study has shown that antibiotics can be chemically redesigned so they are less easily removed by efflux pumps. This allows the antibiotic to remain inside the bacterial cell at higher concentrations, restoring its ability to kill bacteria even when resistance mechanisms are present.
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NewsExperts convened by WHO advise on candidate treatments and vaccines for Ebola disease caused by Bundibugyo virus
In response to the current outbreak of Ebola disease caused by Bundibugyo virus, WHO convened several of its expert and advisory groups to assess potential vaccines and therapeutics for both prevention and treatment of Bundibugyo virus disease (BVD).
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NewsResearchers identify immune ‘energy signature’ linked to tuberculosis protection
Researchers found that circulating monocytes from people with latent TB remain metabolically flexible, allowing them to mount strong antibacterial responses, whereas cells from people with active TB disease show impaired metabolism and weaker responses to infection.
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NewsExperimental HIV vaccine achieves a long-sought goal
In a first for the field, all non-human primates given a new series of vaccines generated antibodies capable of fighting multiple strains of HIV. It brings researchers closer to a vaccine effective against the vast diversity of HIV strains circulating worldwide.
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NewsSeven European countries observe drop in chlamydia notifications especially among young people in 2024
After a decade of general increases in chlamydia cases across Europe, the first signs of a decline suggest a possible common driver. Is it a true reduction and will it be a sustainable one?
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NewsScientists validate a link between autoimmunity in a subset of people with long COVID
A research team has demonstrated that autoimmunity, where the body’s immune system attacks its own tissues, is responsible for the often-debilitating and confounding symptoms of long COVID in a subset of people.
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NewsResearchers may now understand why chikungunya virus infections turn chronic
About half of people infected with chikungunya virus will progress to a chronic form of the disease. A new study finds that chikungunya virus persists in joint-associated macrophages, a specialized type of white blood cell that helps the body defend against pathogens.
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NewsNew study finds neighborhood-level sampling could close equity gap in wastewater disease surveillance
Researchers working with New York State’s wastewater surveillance network found that while the system does a reasonably fair job of including vulnerable populations, it struggles in larger populations when an outbreak is starting, which is when it matters most.
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NewsScientists fight antimicrobial resistance by treating diseases with human antibodies
In a review, researchers highlight the promise of using human monoclonal antibodies (mAbs) to treat patients more effectively and tackle AMR. They say AMR needs to be addressed with multiple and differentiated strategies, and vaccines and mAbs are the most promising tools.
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NewsScientists develop an antifungal aqueous suspension to prevent fungal infections in crops and fruit
Researchers have developed an antifungal aqueous suspension for the prevention of fungal infections in crops and fruit during the pre- and post-harvest stages. The new formulation is aimed at the biotechnology and agricultural sectors.
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NewsMaternal infection: A critical driver of offspring cardiac dysfunction
A new study reveals that maternal infection causes severe metabolic disturbances within the offspring’s heart, most notably enriching differentially expressed genes in lipid, energy, and amino acid metabolism. The infection also heavily suppressed cardiac cell proliferation.
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NewsCommon illnesses, not hantavirus, pose greatest cruise and travel risk
Travelers booked on cruises this summer, or considering booking, shouldn’t change their plans out of fear of hantavirus, one researcher says. They should be aware of more common viral illnesses that occur in cruise settings such as norovirus, seasonal respiratory viruses, COVID-19 and influenza.
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NewsDog daycare leptospirosis outbreak in Los Angeles reveals broader public health risks
A 2021 outbreak of leptospirosis that sickened more than 200 dogs in Los Angeles County reveals critical gaps in vaccination practices and raises broader concerns about the spread of the disease between animals and people.
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NewsScientists identify nearly two dozen antiviral compounds that could treat Ebola virus
Recent advances in artificial intelligence have enabled scientists to identify nearly two dozen antiviral compounds that could potentially treat a rare species of Ebola virus (Bundibugyo virus) currently affecting the Democratic Republic of Congo.
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NewsInsect wing identifying app to tackle tropical disease threat
A mobile app that identifies disease-carrying insects from their wing patterns is being developed as part of a project using AI to help diagnose tropical diseases.
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NewsStudies point to new way to fight potentially deadly Valley Fever
To better understand why Valley Fever spreads in some individuals, researchers found that patients with severe illness had an abnormal immune response. In some cases, the immune system was overactive; in other cases it was underactive.
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NewsNP14 aptamer: A novel biosensing recognition element for mutation-resilient SARS-CoV-2 detection
New research investigated a novel DNA aptamer, NP14, and developed an innovative dual-mode biosensing platform to achieve highly sensitive, mutation-resilient viral detection.
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NewsAutomated EHR alert improved hepatitis B monitoring rates at a primary care clinic
In May 2024, an urban safety-net primary care clinic noted the appearance of a new “care gap” alert in their Epic electronic health record (EHR) system that flagged patients with hepatitis B who were overdue for one blood test, the hepatitis B DNA test.
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NewsICU pneumonia has mortality rates of 37% to nearly 60% in middle-income countries. In high-income countries, rates are16% to 26%
A scientific review evaluated outcomes of adults with community-acquired pneumonia (CAP) admitted to intensive care units (ICUs) in middle-income countries. In contrast to high-income countries, where mortality ranges from 16% to 26%, the study found significantly higher rates in the countries analyzed.