All Infection Prevention & Control articles – Page 18
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NewsTime for an AI checkup: Flaw found in machine learning for sepsis treatment
Researchers found a flaw in many peer-reviewed studies using the AI method known as reinforcement learning as a theoretical guide for the treatment of sepsis. If these flawed systems for sepsis treatment were deployed in a healthcare setting, they would recommend either overtreatment or undertreatment in nearly half of patient states.
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NewsMost cases of HIV persistence in blood following treatment explained by defective copies of the virus
A study based on blood samples strongly suggests that most persistent cases of viral detection, despite ideal HIV drug therapy, are not due to virus transmission or a rebound of active disease.
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NewsNew study highlights maternal-fetal TORCH infection risk
Researchers have assessed long-term trends in TORCH infections in India, a region where reliable data have been lacking. TORCH includes pathogens that cause toxoplasmosis, rubella, cytomegalovirus (CMV), herpes simplex virus and other infections.
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NewsDrug-resistant bacteria found in homes from sewage overflow
A new study shows that sewage overflows in homes can expose people to bacteria that can make them sick, including antibiotic-resistant and multidrug resistant bacteria which can make infections difficult to treat.
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NewsInfections are major ‘health hazard’ for people with diabetes
Infections should be considered a “health hazard” in people living with diabetes, with experts warning that current clinical guidelines fail to reflect a substantial but under-recognised burden of illness, hospitalisation and death. People living with type 1 diabetes, type 2 diabetes and prediabetes face higher risks of infection compared to those without diabetes.
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NewsMaternal RSV vaccine cuts infant hospitalizations by 70%
A study has found that vaccination against respiratory syncytial virus (RSV) during pregnancy reduced the risk of hospitalization in young infants by nearly 70%. It provides early real-world evidence from U.S. clinical care, showing that administering one dose of the maternal RSV vaccine (RSVpreF vaccine) reduces hospitalization related to RSV in young infants.
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NewsData from patients hospitalised with COVID-19 made available to the scientific community
The DIVINE study database has been published. The cohort includes clinical information from 5,813 patients hospitalised with COVID-19 during four waves of the pandemic, between March 2020 and August 2021, across five hospitals in the southern metropolitan area of Barcelona.
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NewsFever and chills can make respiratory diseases more contagious
A new study reveals that when the difference between body temperature and the ambient temperature is greater, the clouds of particles generated by coughing or sneezing disperse more and maintain a higher concentration.
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NewsNew model could help track deadly viruses back to their source
A new predictive model could help scientists more efficiently identify the reservoirs of emerging zoonotic viruses and dangerous pathogens like Ebola that can spill over from animals into humans. It relies on detailed information collected on suspected reservoir species to identify key windows.
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NewsResearcher investigates how a bioengineered peptide can break through harmful bacterial ‘fortresses’ and curb severe infections
A researcher is refining a powerful therapy for drug-resistant bacteria that pierces the gooey coating that anchors and protects such germs from the drugs we take to kill them. She has found that an antimicrobial peptide naturally found in cows weakens the biofilm defenses of Klebsiella pneumoniae bacteria and destroys it.
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NewsResearchers develop new vaccine adjuvant that could make it easier to eradicate polio
Researchers have now come up with a way to modify the injectable polio vaccine so that it can also promote a mucosal immune response. This vaccine could help to achieve polio eradication while avoiding the risks of the oral polio vaccine.
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NewsStudy reveals core values that drive Black and Hispanic parents’ decisions on vaccinating their kids against COVID-19
Persistently low rates of COVID-19 vaccination in Black and Hispanic children suggest that parents in these communities tend to be hesitant about the vaccine for their kids, even when they have received it themselves. A new study sheds light on the factors influencing decisions about vaccination.
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NewsAntibiotics for common sore throats have very limited effect on Strep spread
Antibiotics for sore throats have hardly any preventive effect against serious streptococcal infections in the population, according to a study. Instead, healthcare needs to quickly recognize warning signs of a serious infection.
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News CEPI fast-tracks three Bundibugyo ebolavirus vaccine candidates
The Coalition for Epidemic Preparedness Innovations (CEPI) will urgently accelerate development of three investigational vaccines targeting the Bundibugyo ebolavirus that has caused a rapidly spreading epidemic in the Democratic Republic of the Congo (DRC) and neighbouring Uganda.
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NewsResearchers discover how to turn one germ’s drug resistance into an Achilles’ heel
As Mycobacterium tuberculosis mutates to protect itself from rifampicin, it also creates new weak points that other therapies could exploit. A new study shows that the most common rifampicin-resistance mutation slows bacterial RNA polymerase, creating vulnerabilities that future combination therapies may be able to target.
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NewsGladstone launches Center for PhAIge Therapy to harness AI in the fight against drug-resistant infections
Gladstone Institutes has received funding to establish the Center for PhAIge Therapy, a research center that will develop new phage-based treatments for antibiotic-resistant bacterial infections. The five-year grant makes Gladstone one of three institutions across the country selected to lead this coordinated effort.
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NewsT cells may be key to stopping measles virus—and its deadly relatives
Scientists have discovered how T cells target paramyxoviruses, a viral family that includes measles virus and Nipah virus. Instead of vaccinating against one virus at a time, the researchers found that activating “cross-reactive” T cells may protect against the wider paramyxovirus family.
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NewsBiomaterial made from jackfruit latex is a promising treatment for periodontitis
Researchers have developed a biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin that shows promising efficacy in treating periodontitis. This chronic inflammatory disease of infectious origin leads to the progressive destruction of the tissues supporting the teeth, resulting in bone resorption and loss of attachment.
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NewsStudy identifies serious infection risks linked to targeted cancer therapies
A major real-world study has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Some ADCs were associated with substantial rates of severe neutropenia – dangerously low levels of infection-fighting white blood cells – and related complications.
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NewsPhase 1 clinical trial set to begin on first leishmaniasis vaccine
A phase 1 clinical trial testing the safety of a leishmaniasis vaccine is set to begin in the coming months. The live vaccine, found to be safe in animals, is expected to be tested in humans later this year.