All Institut Pasteur articles
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NewsSingle amino acid change may help viruses jump from bat to human
New research reports that a single amino-acid change alters how a coronavirus protein interacts with the human and bat immune systems, shifting the body’s response to infection.
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NewsAccelerating chikungunya vaccine development in Africa: Launch of the ACT-CHIK Project
Funded by the Global Health EDCTP3 Joint Undertaking, a new €15.3 million project coordinated by Institut Pasteur brings together seven partners across four continents to advance clinical trials and prepare for the manufacturing of a chikungunya vaccine in Africa.
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NewsInsect wing identifying app to tackle tropical disease threat
A mobile app that identifies disease-carrying insects from their wing patterns is being developed as part of a project using AI to help diagnose tropical diseases.
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NewsMetagenomic software advance boosts research into microbial diversity
Researchers studying the diversity of microbes in environmental samples now have access to a new tool that opens the door to cheaper, more accessible analysis of their samples.
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NewsHow microbes protect the lungs against allergies
A study has revealed that microbes protect the lungs from subsequently developing allergies and asthma. This long-term protection is “memorized” not by immune system cells but by fibroblasts, structural cells in the lungs.
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NewsA break in a longstanding mystery about origin of complex life
One of our microbial ancestors was part of a group called the Asgard archaea, which today live primarily in the deep sea and other oxygen-free spaces. Now scientists have found that some Asgards use, or at least tolerate oxygen.
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NewsNeonatal sepsis: using vaginal microbiota to improve predictions
Researchers have found that some identifiable microbial signatures in vaginal swab samples taken at delivery are associated with a risk of neonatal sepsis.
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NewsInstitut Pasteur issues statement on U.S. administration’s attacks against biomedical research, global public health action and vaccination
For several months now, the current U.S. administration has consistently attacked and endeavored to weaken biomedical research and public health action in the United States and worldwide with unparalleled vigor, the Institut Pasteur has said in a new statement.
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NewsSugar transporter discovery offers promising avenue for improving antibiotic efficacy
Scientists have recently demonstrated that aminoglycosides enter bacteria by using sugar transporters. They have also successfully doubled the number of transporters, even in the most resistant Escherichia coli strains, thus improving antibiotics’ penetration rate and efficacy.
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NewsDNA from Napoleon’s 1812 army identifies the pathogens likely responsible for the army’s demise during their retreat from Russia
Microbial paleogenomicists extracted DNA from the teeth of soldiers from Napoleon’s ill-fated invasion of the Russian Empire and found no trace of typhus. Instead, they identified two pathogens known to cause enteric fever and relapsing fever.
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NewsFungal toxin offers colonization support - in small doses
The yeast fungus Candida albicans not only uses the toxin candidalysin to cause infections, but also to colonize the oral mucosa inconspicuously – but only in finely balanced amounts. Too little toxin prevents oral colonization, too much triggers the immune system.
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NewsStudy advances understanding of immune system’s crucial role in phage therapy
Scientists have assessed the effectiveness of phage therapy in treating pneumonia. What they discovered about the mechanisms behind phage therapy could inform treatments in clinical settings to help patients facing similarly stubborn infections.
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NewsNew RNA test for African trypanosomiasis in livestock aids control efforts
A new state-of-the-art diagnostic test for animal African trypanosomiasis could detect sentinels of infection in domestic animals and aid control efforts.
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NewsUncovered: A long-lasting history of leprosy in the Americas
A new study challenges the view that leprosy is a disease that was introduced into the Americas during European colonization. A strain of leprosy-causing mycobacterium, Mycobacterium lepromatosis, infected humans in the Americas before European contact.
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NewsHow the plague bacillus became less virulent, prolonging the duration of two major pandemics
Scientists have discovered that the evolution of a gene in the bacterium that causes bubonic plague, Yersinia pestis, may have prolonged the duration of two major pandemics. Modifying the copy number of a specific virulence gene increases the length of infection.
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NewsMOPEVACLAS vaccine candidate for Lassa fever enters clinical trials
After more than 20 years of research on arenaviruses, researchers have developed an original vaccine platform known as MOPEVAC. A Phase Ia clinical trial is set to begin for the platform’s first vaccine candidate, which targets Lassa fever, a hemorrhagic fever responsible for thousands of deaths worldwide each year.
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NewsHepatitis B: new rapid diagnostic test to halt mother-to-child transmission
Scientists have assessed a new rapid diagnostic test to identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This diagnostic tool could help eliminate hepatitis B by preventing mother-to-child transmission during childbirth.
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NewsThe Institut Pasteur joins the Stand Up for Science community
Echoing the Stand Up for Science Day initiated in the United States, scientists and academics in France are calling for mobilization actions in every city.
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NewsNewly launched Enodia Therapeutics is a biotech company with a new approach for targeted protein degradation
Argobio and the Institut Pasteur have announced the launch of Enodia Therapeutics, a groundbreaking French biotech company dedicated to block and degrade disease-causing proteins for treating cancer, inflammatory diseases and viral infections.
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NewsMpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.