All Institut Pasteur articles
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NewsStudy advances understanding of immune system’s crucial role in phage therapy
Scientists have assessed the effectiveness of phage therapy in treating pneumonia. What they discovered about the mechanisms behind phage therapy could inform treatments in clinical settings to help patients facing similarly stubborn infections.
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NewsNew RNA test for African trypanosomiasis in livestock aids control efforts
A new state-of-the-art diagnostic test for animal African trypanosomiasis could detect sentinels of infection in domestic animals and aid control efforts.
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NewsHow the plague bacillus became less virulent, prolonging the duration of two major pandemics
Scientists have discovered that the evolution of a gene in the bacterium that causes bubonic plague, Yersinia pestis, may have prolonged the duration of two major pandemics. Modifying the copy number of a specific virulence gene increases the length of infection.
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NewsUncovered: A long-lasting history of leprosy in the Americas
A new study challenges the view that leprosy is a disease that was introduced into the Americas during European colonization. A strain of leprosy-causing mycobacterium, Mycobacterium lepromatosis, infected humans in the Americas before European contact.
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NewsMOPEVACLAS vaccine candidate for Lassa fever enters clinical trials
After more than 20 years of research on arenaviruses, researchers have developed an original vaccine platform known as MOPEVAC. A Phase Ia clinical trial is set to begin for the platform’s first vaccine candidate, which targets Lassa fever, a hemorrhagic fever responsible for thousands of deaths worldwide each year.
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NewsHepatitis B: new rapid diagnostic test to halt mother-to-child transmission
Scientists have assessed a new rapid diagnostic test to identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This diagnostic tool could help eliminate hepatitis B by preventing mother-to-child transmission during childbirth.
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NewsThe Institut Pasteur joins the Stand Up for Science community
Echoing the Stand Up for Science Day initiated in the United States, scientists and academics in France are calling for mobilization actions in every city.
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NewsNewly launched Enodia Therapeutics is a biotech company with a new approach for targeted protein degradation
Argobio and the Institut Pasteur have announced the launch of Enodia Therapeutics, a groundbreaking French biotech company dedicated to block and degrade disease-causing proteins for treating cancer, inflammatory diseases and viral infections.
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NewsMpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.
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NewsScientists harness microbiota as ally for predicting individual sensitivity to food additives
Researchers developed a human microbiota modelling system capable of predicting each person’s sensitivity to an emulsifier, using a simple stool sample, paving the way for a personalised nutrition approach based on the gut microbiota.
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NewsSystem to auto-detect new variants will inform better response to future infectious disease outbreaks
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.
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NewsScientists find a vulnerability in antibiotic resistance mechanism
Superbugs, bacteria that are immune to multiple antibiotics, pose a great challenge to modern medicine. Researchers from the B CUBE - Center for Molecular Bioengineering at TUD Dresden University of Technology and Institut Pasteur in Paris identified a weakness in the bacterial machinery that drives antibiotic resistance adaptation. Their findings, ...
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NewsFrom Yemen to Mayotte, the spread of a highly drug-resistant cholera strain
Scientists have revealed the spread of a highly drug-resistant cholera strain. The strain is resistant to ten antibiotics – including azithromycin and ciprofloxacin, two of the three recommended for treating cholera – and was identified for the first time in Yemen in 2018-2019.
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NewsResearchers call for global discussion about possible risks from ‘mirror bacteria’
A group of researchers has published new findings on potential risks from the development of mirror bacteria — synthetic organisms in which all molecules have reversed chirality (i.e. are ‘mirrored’).
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NewsA new tool to predict the most effective phage cocktail
Researchers have developed a simple and effective new tool that recommends the best possible phage cocktail for a given patient. Paving the way for personalized phage therapies to treat antibiotic-resistant bacterial infections.
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NewsGlobal researchers unite their expertise to boost infectious diseases research across the Asia-Pacific region
Singapore’s Agency for Science, Technology and Research Infectious Diseases Labs and France’s Institut Pasteur have signed a Memorandum of Understanding to address the urgent health threats posed by the rise of tropical infectious diseases in the Asia-Pacific region.
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NewsFirst sustained remission of HIV infection following a bone marrow transplant in the absence of protective mutation
A total of seven individuals worldwide (two patients in Berlin and patients in London, Düsseldorf, New York, City of Hope and Geneva) are considered likely to have been cured or to be in long-term remission of HIV infection after receiving a bone marrow transplant to treat blood cancer. ...
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NewsCRISPR gene scissors switch off with built-in timer
Researchers have discovered a timer integrated into the CRISPR gene scissors that enables the gene scissors to switch themselves off.
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NewsResearchers reveals why recombinant BCG induces a stronger and longer-lasting response
Researchers are working on a more potent version of the BCG vaccine that protects against TB. While the conventional immunizer reduced infection by 90% in experiments with mice, the recombinant BCG increased protection rates to 99%.
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NewsOlympics: how many days does it take for mosquitoes in Greater Paris to transmit arboviruses?
In the run-up to the Olympic Games, scientists have demonstrated that the tiger mosquito, now present in Greater Paris, is capable of transmitting five viruses - West Nile, chikungunya, Usutu, Zika and dengue - within different time frames.