All La Jolla Institute for Immunology articles
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News
How Zika virus knocks out our immune defenses
Scientists have made striking discoveries regarding the different infection mechanisms of Zika and dengue virus of the same viral family. These understandings pave the way for vaccine development to combat flaviviruses with similarities.
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As dengue spreads, researchers discover a clue to fighting the virus
Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study. Most children who experienced two or more dengue infections showed very minor symptoms—or no symptoms at all—when they caught the virus again.
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New research reveals how location influences how our immune system fights disease
Researchers have revealed how cells known as tissue-resident memory CD8 T cells play unique and specialized roles based on where they are located within the small intestine, providing a local first line of defense against re-infection.
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New mouse models offer valuable window into COVID-19 infection
Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19 because their cells were engineered to include two important human molecules that are involved in infection of human cells.
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Discovery paves the way for antivirals against Ebola virus and its deadly relatives
The first detailed, complete images of the Ebola virus nucleocapsid may accelerate the development of antivirals to combat several filoviruses at once.
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A new viral target could help combat the global measles resurgence
A multinational research team has identified a novel way to attack measles, paving the way for new vaccines and antiviral drugs that could help combat the virus’s global resurgence.
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‘Late-rising’ T cells combat a stubborn virus
A subset of CD4+ “helper” T cells may help a person fight cytomegalovirus and reduce the chances of the virus spreading from person to person.
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T cells tackle new ‘Pirola’ SARS-CoV-2 variant
Scientists harness bioinformatics to predict how T cells may adapt to fighting the highly mutated Pirola variant.
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Scientists reveal inner workings of Ebola’s ‘viral factories’
A new study reveals how the Ebola virus’s replication machinery forms fascinating microscopic structures inside host cells that become viral factories.