Latest News in WAAW – Page 25
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Missing puzzle piece discovered that influences sensitivity of gut bacterium to antibiotics
Scientists identify the small RNA that influences the sensitivity of the intestinal pathogen Bacteroides thetaiotaomicron to certain antibiotics.
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Landmark NHS deal gives patients access to groundbreaking light-activated antimicrobial to combat antimicrobial resistance
A new light-activated antimicrobial that kills all types of bugs – viruses, bacteria, and fungi – in minutes without generating resistance is being adopted by NHS hospitals to reduce surgical infections.
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Researchers discover evolutionary “tipping point” in fungi
Scientists have found a ‘tipping point’ in the evolution of fungi that throttles their growth and sculpts their shapes, demonstrating how small changes in environmental factors can lead to huge changes in evolutionary outcomes.
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African catfish skin mucus yields promising antibacterial compound
Scientists report they have extracted a compound with powerful antibacterial properties from the skin of farmed African catfish.
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Researchers invent artificial intelligence model to design new superbug-fighting antibiotics
Researchers have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.
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Membrane-producing enzyme offers promising target
The enzyme LpxC, which catalyzes the first irreversible step in the biosynthesis of the outer membrane of Gram-negative bacteria, is a highly promising target for the development of antibiotics.
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Antibiotics combat the gut bacteria that contribute to the pathogenesis of COVID-19
New research indicates that antibiotics can effectively target bacteria in the gut that harbor the virus that causes COVID-19 and produce toxin-like peptides that contribute to COVID-19-related symptoms. In the study, which involved 211 participants and was published in the Journal of Medical Virology, individuals who received ...
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Warning signs herald the development of antibiotic resistance
A new study shows how heteroresistance, a transient resistance common in many bacteria, can act as a precursor to the development of antibiotic resistance.
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Researchers report rise in global fungal drug-resistant infections
Epidemiological data indicates that a rise in severe fungal infections has resulted in over 150 million cases annually and almost 1.7 million fatalities globally.
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Age and sex associated with patient’s likelihood of antimicrobial resistance
A person’s age, sex and location are correlated with the chance that they have a bloodstream infection that is resistant to antibiotics, according to a new study.
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Researchers uncover how viruses choose whether to become nasty or not
Researchers have deciphered a novel complex decision-making process that helps viruses choose to turn nasty or stay friendly to their bacterial host.
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Steroid drugs used for HRT can combat E. coli and MRSA
New research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
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Study reveals “considerable farmer knowledge” on different aspects of antibiotics risk
A study has revealed “considerable farmer knowledge” on different aspects of antibiotics risks – including antimicrobial resistance – associated with their use on livestock in Kenya.
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Phage enzyme deployed against drug-resistant bacteria
Given the worldwide prevalence of drug-resistance bacteria, the research fraternity is on the lookout for alternative bactericidal treatment approaches. In a recent study, Japanese researchers have now compared bacteriophage-derived enzymes for combating drug-resistant bacteria. Source: National Institute of Allergy and Infectious Diseases (NIAID) Digitally-colorized scanning electron micrograph (SEM) ...
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New dual therapeutic strategy shows promise against multidrug-resistant salmonella
A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in Scientific Reports. Source: CDC/ Antibiotic Resistance Coordination and Strategy Unit Medical illustration of drug-resistant, nontyphoidal Salmonella sp. ...
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Study probes what makes a pathogen antibiotic-resistant
Researchers describe how two notable pathogens—Escherichia coli and Acinetobacter baumannii—employ distinctly different tools to fend off antibiotic attack.
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Researchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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First atom-level structure of packaged viral genome reveals new properties, dynamics
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets, researchers report.
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£1.5m donation drives UK-Japan collaboration in antimicrobial research
A £1.5 million donation will drive joint research into antimicrobial resistance (AMR) by scientists in the UK and Japan.
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Possible ‘Trojan Horse’ found for treating stubborn bacterial infections
Bacteria can be tricked into sending death signals to stop the growth of their slimy, protective homes that lead to deadly infections, a new study demonstrates.