Latest News in WAAW – Page 28
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Fungus yields different pathway to the same pharmaceutically important substance
Researchers analyze a fungal biosynthetic pathway and discover a capable enzyme.
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Viruses can cause multiple myeloma cancer, case study finds, offering hope for treatment
An unusual clinical case has led to the discovery that hepatitis B and C viruses are one of the causes of multiple myeloma, and that eliminating infection with antivirals is often the way to fight this type of cancer.
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Antibiotics highjack bacterial immunity
Molecular defense system protects bacteria from viruses and at the same time makes them susceptible to antibiotics.
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Phages found that bring slumbering bacteria out of deep sleep and then kill them
Researchers questioning whether evolution might have produced bacteriophages that specialise in dormant bacteria and could be used to target them have now shown that such phages, though rare, do indeed exist.
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Trial offers insights into treatment options for bloodstream infections
An international clinical trial has been able to gain decisive new insights into the treatment of bloodstream infections with the pathogen Staphylococcus aureus (SAB).
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New antibiotic resistant species of bacteria found in hospital wastewater system
Researchers at University of Limerick in Ireland have discovered a new species of bacteria that is resistant to antibiotics.
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Study opens lid on how Candida evolves and adapts to humans
Scientists have identified hundreds of genes subject to recent, clinically-relevant selection in six species of the fungal pathogen Candida.
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Scientists reveal role of notorious cell subpopulation in antibiotic failure
Scientists provide the best evidence to date for the significance of bacterial persister cells in the failure of antibiotics in the clinic.
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Antibiotic use is not the only driver of superbugs
Researchers have analysed the rise of antibiotic resistance over the last 20 years in the UK and Norway, highlighting that antibiotic use is not the only factor in the increase.
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War on bugs can’t be won, researchers declare
A new paper calls for antimicrobial resistance to be reframed as a sustainability issue.
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Phages pay heavy price for environmental intel - but it’s worth it
Phages, the viruses that infect bacteria, will pay a high growth-rate cost to access environmental information that can help them choose which lifecycle to pursue, according to a study. Source: L. F. Lee; J. A. Boezi Bacteriophage gh-1 for Pseudomonas putida. Yigal Meir and colleagues at Ben-Gurion ...
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Higher viral load during HIV infection can shape viral evolution
A new paper finds that HIV populations in people with higher viral loads also have higher rates of viral recombination.
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Crop spray could lead to mass resistance in new-generation antifungal treatments
An agricultural fungicide approved in the US and currently under consideration by authorities worldwide could have a devastating effect on a new drug for one of world’s deadliest infectious diseases.
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Novo Nordisk Foundation partners with CARB-X to fight drug-resistant infections
The Novo Nordisk Foundation is committing up to $25 million to support the early-stage development of innovative tools to prevent, diagnose and treat the most dangerous drug-resistant bacterial infections. The three-year grant will go to the Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X), the leading global non-profit public-private partnership in this ...
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Scientists reveal why chicken farms are a breeding ground for AMR bacteria
Scientists are one step closer to understanding how bacteria, such as E. coli and Salmonella enterica, share genetic material which makes them resistant to antibiotics.
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Gut bacteria combinations protect stem cell transplantation patients from dangerous immune reactions
Researchers have shown that graft versus host disease (GvHD) is less common when certain microbes are present in the gut. In the future, it may be possible to deliberately bring about this protective composition of the microbiome.
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New approach could address antibiotic resistance to Mycobacterium abscessus
Scientists have designed new versions of the drug spectinomycin that overcome efflux, the main mechanism driving resistance.
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African One Health network launched to prevent disease
A new network aims to create the conditions for improved sustainable and locally led management of antimicrobial resistance and neglected tropical diseases in seven countries in sub-Saharan Africa.
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Dr Ben Swift named as winner of Basil Jarvis Prize
Dr Ben Swift of the Royal Veterinary College in the UK has been named as this year’s winner of the Basil Jarvis Prize for microbiology.
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New antibiotics make TB bacterium less pathogenic for humans
Researchers have identified new, antibiotic molecules that target Mycobacterium tuberculosis and make it less pathogenic for humans.