Latest News in WAAW – Page 38
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Drugs pipeline rife with strategies to combat MRSA
A host of new antimicrobial strategies are in the development pipeline that could provide hope for healthcare sectors battling multi-drug resistant Staphylococcus aureus infections.
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Study uncovers how Leishmania parasite adapts so quickly to drugs
Scientists probing the parasite’s gene expression regulation during mRNA translation have discovered how it is able to preemptively and quickly adapt and respond to drug treatments.
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Staph mechanism for resistance to last resort drug is uncovered
New research has revealed the mechanism of transcriptional regulation via S-nitrosylation for resistance to last resort drug vancomycin in Staphylococcus aureus.
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Nanorobots seek and destroy fungal infections in the mouth
Researchers have developed a new way to rapidly and precisely eradicate fungal infections in the mouth by using nanorobots guided by magnets.
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AI deployed to find promising antibiotic to fight evasive hospital superbug
Scientists have used artificial intelligence to discover a new antibiotic which could be used to fight a deadly, drug-resistant pathogen that strikes vulnerable hospital patients.
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AI-found drug may combat drug-resistant infections
Scietntists used a machine-learning algorithm to identify a compound that kills Acinetobacter baumannii, a bacterium that lurks in many hospital settings.
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Microplastics changing gut microbiomes of wild seabirds
An international team of scientists has found evidence that microplastics in the digestive tract of seabirds altered the microbiome of the gut – increasing the presence of pathogens and antibiotic-resistant microbes, while decreasing the beneficial bacteria found in the intestines.
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Deadly virus structures pinpoint new targets for Lassa vaccine design
By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a research team has identified new antibodies and vaccine targets.
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Anti-microbial nanonets ease inflammation during sepsis
Pharmaceutical scientists have developed multi-functional synthetic peptide nanonets for relieving inflammation caused by bacterial infection. This is achieved by concurrent trapping of bacterial endotoxins and pro-inflammatory cytokines.
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Researchers fight Lyme disease with local herbs
Scientists are investigating whether medicinal plants growing in Estonia could be used to fight Lyme disease and destroy the bacteria causing it.
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Public embrace phages as antibiotic alternative
The public are in favour of the development of bacteria-killing viruses as an alternative to antibiotics – and more efforts to educate will make them significantly more likely to use the treatment, a new study shows.
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Unusual cellular metabolism in fungi linked to AMR
Scientists have discovered that aberrant cellular metabolism in Candida fungi is linked to drug resistance, potentially opening up new possible pathways to antimetabolite therapies.
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Neglected 80yo antibiotic tackles AMR bacteria
An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study.
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Peptide combats multidrug-resistant bacteria in less than one hour
A synthetic peptide inspired by molecules secreted by the probiotic bacterium Lactobacillus plantarum has presented promising antibacterial results within one hour in laboratory trials.
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Filamentous phage structure mapped for the first time
Researchers have mapped out what a commonly-used form of phage looks like, which will help researchers design better uses in future.
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Warning over lack of ‘substantial evidence’ for FDA approved antibiotic
Drugs approved in the US require “substantial evidence” that they are effective, but an investigation by The BMJ into the recent approval of the antibiotic Recarbrio from Merck suggests that these standards are being bypassed.
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Tracking AMR in E. coli isolated from swine reveals worrying trends
Scientists have carried out the first surveillance study in the US that looks at antimicrobial resistance in E. coli from swine at slaughter.
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Resistant Candida auris on rise in Germany, setting off alarm signals
The number of cases of Candida auris has increased in Germany in recent years, adding to outbreaks worldwide, a new study has revealed.
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Traditional medicine plant could combat drug-resistant malaria
Researchers have identified compounds in the leaves of a particular medicinal Labrador tea plant used throughout the First Nations of Nunavik, Canada, and demonstrated that one of them has activity against the parasite responsible for malaria.
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Bacteria evolve antibiotic resistance quickly by rejigging pumps
Bacteria can rapidly evolve resistance to antibiotics by adapting special pumps to flush them out of their cells, according to new research from the Quadram Institute and University of East Anglia.