All Matthew Chang articles
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NewsFrom gut to brain: scientists engineer bacteria to treat severe liver-related brain dysfunction
In vivo studies showed that programmable “living medicines” could reduce brain toxins and prevent neurological symptoms of hepatic encephalopathy, offering distinct advantages over a widely prescribed antibiotic.
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NewsGround-breaking technique deploys bacterium to deliver drugs directly to the brain
A landmark study using the nasal bacteria technique promises new treatments for neurological disorders by bypassing the blood-brain barrier.
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NewsBioengineered yeast microbes as targeted drug delivery systems
Researchers from the Yong Loo Lin School of Medicine (NUS Medicine) have developed a groundbreaking way to engineer yeast (Saccharomyces cerevisiae) to create microbial communities that can perform complex tasks and self-regulate their composition in response to external signals. Source: Alexander Klepnev Baker’s yeast cells. Calcofluor ...
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NewsScientists construct a synthetic yeast genome
The yeast genome contains redesigned chromosome sequences that can shed light on the impact of genetic variations on individual traits and potentially be used to reveal the causes of genetic diseases