All mpox articles
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NewsMpox outbreak in 2022 caused by less severe form of the virus
The strain of Mpox behind the 2022 outbreak was a weakened form of the virus, which may have helped to spread it faster, a new study reports. The findings show that the virus acquired mutations before it spread globally.
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NewsA full-control strategy could cut simulated mpox infections by 97.8%, suggests mathematical model
Researchers have used mathematical modeling to explore how different interventions could work together to limit Mpox transmission. The model captures Mpox transmission dynamics across two interacting populations: humans and rodents.
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NewsSurvey highlights persistent uncertainty on STI vaccines
A nationally representative survey of empaneled adults finds that while most Americans understand how STIs spread, there are significant gaps in public knowledge about which infections can be prevented through vaccination.
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NewsMpox study reveals hidden infections may fuel spread
A study shows that in mid- to late 2024, mpox was far more common among men who have sex with men than previously thought. Individuals without symptoms accounted for most infections and likely played a prominent role in transmission, contrary to prior assumptions that people had to be symptomatic to spread the disease.
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NewsWildlife trade increases pathogen transmission
A study combining forty years of legal and illegal wildlife import-export data with compilations of host–pathogen relationships found that wild mammals that are traded are 1.5 times more likely to share infectious agents with humans than those that are not involved in trade.
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NewsMpox immune test validated during Rwandan outbreak
An antibody test for the infectious disease Mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting.
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NewsFire-footed rope squirrels identified as a natural reservoir for monkeypox virus
A cross-species transmission event documented in Côte d’Ivoire provides new insights into the spread of mpox in the wild.
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News58% of patients affected by 2022 mpox outbreak report lasting physical symptoms
A cohort study found that more than half of those diagnosed with mpox during the 2022 outbreak still had lingering physical effects 11 to 18 months later.
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NewsGlobal Virus Network launches multi-country mpox diagnostic evaluation to close global preparedness gaps
The Global Virus Network has initiated one of the first coordinated, multi-country evaluations of rapid point-of-care mpox diagnostics, a critical step to prevent resurgence and ensure the world is better prepared for future epidemics.
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NewsTropical diseases: Global health meeting showcases resilience of field under fire
At a moment of monumental challenges for global health, thousands of researchers, clinicians and public health professionals from over 100 countries will gather in Toronto for the 2025 Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).
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NewsScientists identify three potent human antibodies against mpox, paving the way for new protective therapies
Researchers have discovered three powerful monoclonal antibodies from a person who had previously been infected with mpox (formerly known as monkeypox).
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NewsWHO announces that mpox remains a public health emergency of international concern
WHO Director-General Dr Tedros Adhanom Ghebreyesus has announced that the mpox upsurge continues to meet the criteria of a public health emergency of international concern (PHEIC) set forth in the International Health Regulations (IHR).
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NewsGenomic data shows widespread mpox transmission in West Africa prior to 2022 global outbreak
Mpox was transmitted among humans in Nigeria for eight years before sparking the international outbreak in 2022. Using genomic tracing, the researchers estimate that the virus’s ancestor first emerged in southern Nigeria in August 2014.
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NewsResearchers valuate the safety and efficacy of a smallpox vaccine for preventing mpox
Researchers explored the viability and safety of LC16m8, an attenuated vaccinia virus vaccine, to prevent monkeypox. The study evaluated the immunogenicity and safety of LC16m8 across three animal species.
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NewsMpox could become a serious global threat, scientists warn
Mpox has the potential to become a significant global health threat if taken too lightly. Scientists highlight how mpox – traditionally spread from animals to humans – is now showing clear signs of sustained human-to-human transmission.
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NewsResearchers develop machine learning model to predict virus reservoirs
A new artificial intelligence tool could aid in limiting or even prevent pandemics by identifying animal species that may harbor and spread viruses capable of infecting humans.
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NewsStudy yields new data on Mpox vaccine effectiveness in people with HIV
A new study has found that a single dose of the Imvanex vaccine provides protection against Mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer sufficient protection. All at-risk groups, especially people with HIV, should receive the second dose of the vaccine as recommended.
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NewsTecovirimat is safe but ineffective as treatment for clade II mpox
The antiviral drug tecovrimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial.
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NewsNew insights offer hope for developing antiviral therapeutics targeting mpox
New research provides novel perspectives on the biological function of G4s in the lifecycle of MPXV and offer potential avenues for developing antiviral therapeutics targeting mpox prevention and treatment.
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NewsOptical biosensor rapidly detects monkeypox virus
Researchers have developed an optical biosensor that can rapidly detect monkeypox, the virus that causes mpox. The technology could allow clinicians to diagnose the disease at the point of care rather than wait for lab results.