All Mycobacterium tuberculosis articles
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NewsGeneXpert MTB/RIF technology can distinguish non-tuberculous mycobacterial infection
Xpert Mycobacterium tuberculosis/rifampicin (Xpert MTB/RIF) in alveolar lavage fluid can not only detect rifampicin resistance but also distinguish pulmonary tuberculosis (TB) from non-tuberculosis mycobacterial (NTM) pulmonary disease.
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NewsStudies probe how novel inhibitors can switch efflux pumps off in TB bacteria
Two new studies aim to both identify and understand how novel inhibitors can switch efflux pumps off in the bacteria Mycobacterium tuberculosis.
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NewsStudy uncovers how certain antibodies help fight tuberculosis
Researchers collected the largest library of monoclonal antibodies to Mycobacterium tuberculosis (Mtb) and identified specific antibody features that significantly limit its growth.
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NewsStudy discovers DNA switch that controls TB growth – and could help unlock its antibiotic resistance secrets
The bacteria that cause tuberculosis (TB) may have an ‘on-off switch’ that lets them pause and restart growth, according to a new study which helps explain why TB is so hard to treat with antibiotics and could pave the way for better drugs.
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NewsDNA test detects three times more lung pathogens than traditional methods
A study on the application of Metagenomic next-generation sequencing (mNGS) found it can achieve early detection of pathogens and accelerate development of targeted anti-infection treatment plans, improving treatment outcomes and patient prognosis.
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NewsNew molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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NewsDr. Sabine Ehrt named Chair of the Department of Microbiology and Immunology at Weill Cornell Medicine
Dr. Sabine Ehrt, an internationally renowned leader in tuberculosis research, has been appointed chair of the Department of Microbiology and Immunology at Weill Cornell Medicine.
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NewsA new smartphone-sized device can test for tuberculosis - here’s why that matters for children
Scientists have designed the first-of-its-kind portable device to deliver fast, low-cost TB results — no lab required — to fight the world’s deadliest infectious disease.
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NewsResearchers use AI to improve diagnosis of drug-resistant infections
Scientists have developed a new AI-based method that more accurately detects genetic markers of antibiotic resistance in Mycobacterium tuberculosis and Staphylococcus aureus — potentially leading to faster and more effective treatments.
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NewsMolecular stool test could improve detection of tuberculosis in adults with HIV
A prospective multicentre study highlights the potential of the Xpert MTB/Ultra stool test for diagnosing tuberculosis in people living with HIV.
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NewsSusceptibility to bovine TB in cattle traced to key genes
A new study identifying genetic factors contributing to bovine tuberculosis (bTB) susceptibility has found several key genes and pathways involved in the bovine response to Mycobacterium bovis, the causative agent of the disease in cattle.
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NewsFour advances that could change tuberculosis treatment
World Tuberculosis Day commemorates Robert Koch’s discovery of the source bacterium Mycobacterium tuberculosis. Scientists are still refining TB diagnosis methods and treatment strategies - some of the latest innovations are revealed here.
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NewsTB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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NewsDesigning self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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NewsNovel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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NewsAI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
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NewsSelf-destructing vaccine offers enhanced protection against tuberculosis in monkeys
A self-destructing vaccine administered intravenously provides additional safety and protection against tuberculosis (TB) in macaque monkeys, suggests new research.
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NewsTuberculosis strains resistant to new drugs are transmitted between patients
Researchers have identified 514 Mycobacterium tuberculosis strains that are resistant to TB drugs, including both old and new treatment regimens, in 27 countries across four continents. 28% of these strains were transmitted directly from one patient to another.
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NewsSystem to auto-detect new variants will inform better response to future infectious disease outbreaks
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.
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NewsPeat-bog fungi produce substances that kill tuberculosis-causing bacteria
An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to the bacterium that causes the human disease tuberculosis.