All Mycobacterium tuberculosis articles
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NewsNew ‘cough simulator’ mimics TB transmission with unprecedented accuracy
Researchers have developed a new experimental system called Transmission Simulation System (TSS) that replicates the airborne transmission of TB – by simulating the human cough – with unparalleled realism and never-before-seen precision.
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OpinionSafety and nutritional claims for raw milk
Robert F Kennedy Jr. famously advocates drinking raw milk and promotes its benefits. But how safe is unpasteurised milk? Nicola Holden and Gil Domingue, who sit on Applied Microbiology International’s Food Security Scientific Advisory Group, take a deep dive into the science.
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NewsSeventy-year-old Parkinson’s drug shows promise against tuberculosis
A medication developed in the 1950s to treat Parkinson’s disease may offer a powerful new tool in the fight against tuberculosis. The study found that benztropine can dramatically reduce levels of TB-causing bacteria by boosting the body’s natural immune response.
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NewsSkin test reagent proves effective and safe for TB diagnosis in children
A new class of skin test reagents based on Mycobacterium tuberculosis (MTB)-specific antigens has been developed. A phase III clinical trial suggests that C-TST is an effective and safe option for diagnosing pediatric TBI.
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NewsTB bacteria play possum to evade vaccines
Scientists studied how the TB bacterium evades an immune system primed to destroy it. Their genetic study in mice reveals that TB bacteria can essentially play dead to outlast the immune response.
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NewsResearch opens up new avenue for tuberculosis drug discovery
Researchers studied an enzyme from the TB bacterium called alpha-methylacyl-CoA racemase (MCR) which helps the bacterium use cholesterol as an energy source. Blocking this enzyme would therefore starve the bacterium of a major food source, helping to treat TB infections.
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NewsGeneXpert MTB/RIF technology can distinguish non-tuberculous mycobacterial infection
Xpert Mycobacterium tuberculosis/rifampicin (Xpert MTB/RIF) in alveolar lavage fluid can not only detect rifampicin resistance but also distinguish pulmonary tuberculosis (TB) from non-tuberculosis mycobacterial (NTM) pulmonary disease.
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NewsStudies probe how novel inhibitors can switch efflux pumps off in TB bacteria
Two new studies aim to both identify and understand how novel inhibitors can switch efflux pumps off in the bacteria Mycobacterium tuberculosis.
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NewsStudy uncovers how certain antibodies help fight tuberculosis
Researchers collected the largest library of monoclonal antibodies to Mycobacterium tuberculosis (Mtb) and identified specific antibody features that significantly limit its growth.
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NewsStudy discovers DNA switch that controls TB growth – and could help unlock its antibiotic resistance secrets
The bacteria that cause tuberculosis (TB) may have an ‘on-off switch’ that lets them pause and restart growth, according to a new study which helps explain why TB is so hard to treat with antibiotics and could pave the way for better drugs.
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NewsDNA test detects three times more lung pathogens than traditional methods
A study on the application of Metagenomic next-generation sequencing (mNGS) found it can achieve early detection of pathogens and accelerate development of targeted anti-infection treatment plans, improving treatment outcomes and patient prognosis.
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NewsNew molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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NewsDr. Sabine Ehrt named Chair of the Department of Microbiology and Immunology at Weill Cornell Medicine
Dr. Sabine Ehrt, an internationally renowned leader in tuberculosis research, has been appointed chair of the Department of Microbiology and Immunology at Weill Cornell Medicine.
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NewsA new smartphone-sized device can test for tuberculosis - here’s why that matters for children
Scientists have designed the first-of-its-kind portable device to deliver fast, low-cost TB results — no lab required — to fight the world’s deadliest infectious disease.
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NewsResearchers use AI to improve diagnosis of drug-resistant infections
Scientists have developed a new AI-based method that more accurately detects genetic markers of antibiotic resistance in Mycobacterium tuberculosis and Staphylococcus aureus — potentially leading to faster and more effective treatments.
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NewsMolecular stool test could improve detection of tuberculosis in adults with HIV
A prospective multicentre study highlights the potential of the Xpert MTB/Ultra stool test for diagnosing tuberculosis in people living with HIV.
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NewsSusceptibility to bovine TB in cattle traced to key genes
A new study identifying genetic factors contributing to bovine tuberculosis (bTB) susceptibility has found several key genes and pathways involved in the bovine response to Mycobacterium bovis, the causative agent of the disease in cattle.
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NewsFour advances that could change tuberculosis treatment
World Tuberculosis Day commemorates Robert Koch’s discovery of the source bacterium Mycobacterium tuberculosis. Scientists are still refining TB diagnosis methods and treatment strategies - some of the latest innovations are revealed here.
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NewsTB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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NewsDesigning self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.