All Mycobacterium tuberculosis articles
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Dr. Sabine Ehrt named Chair of the Department of Microbiology and Immunology at Weill Cornell Medicine
Dr. Sabine Ehrt, an internationally renowned leader in tuberculosis research, has been appointed chair of the Department of Microbiology and Immunology at Weill Cornell Medicine.
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A new smartphone-sized device can test for tuberculosis - here’s why that matters for children
Scientists have designed the first-of-its-kind portable device to deliver fast, low-cost TB results — no lab required — to fight the world’s deadliest infectious disease.
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Researchers use AI to improve diagnosis of drug-resistant infections
Scientists have developed a new AI-based method that more accurately detects genetic markers of antibiotic resistance in Mycobacterium tuberculosis and Staphylococcus aureus — potentially leading to faster and more effective treatments.
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Molecular stool test could improve detection of tuberculosis in adults with HIV
A prospective multicentre study highlights the potential of the Xpert MTB/Ultra stool test for diagnosing tuberculosis in people living with HIV.
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Susceptibility to bovine TB in cattle traced to key genes
A new study identifying genetic factors contributing to bovine tuberculosis (bTB) susceptibility has found several key genes and pathways involved in the bovine response to Mycobacterium bovis, the causative agent of the disease in cattle.
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Four advances that could change tuberculosis treatment
World Tuberculosis Day commemorates Robert Koch’s discovery of the source bacterium Mycobacterium tuberculosis. Scientists are still refining TB diagnosis methods and treatment strategies - some of the latest innovations are revealed here.
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TB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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Designing self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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Novel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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AI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
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Self-destructing vaccine offers enhanced protection against tuberculosis in monkeys
A self-destructing vaccine administered intravenously provides additional safety and protection against tuberculosis (TB) in macaque monkeys, suggests new research.
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Tuberculosis strains resistant to new drugs are transmitted between patients
Researchers have identified 514 Mycobacterium tuberculosis strains that are resistant to TB drugs, including both old and new treatment regimens, in 27 countries across four continents. 28% of these strains were transmitted directly from one patient to another.
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System to auto-detect new variants will inform better response to future infectious disease outbreaks
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.
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Peat-bog fungi produce substances that kill tuberculosis-causing bacteria
An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to the bacterium that causes the human disease tuberculosis.
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Researchers reveal why a key tuberculosis drug works against resistant strains
Research has uncovered why a relatively new antibiotic for tuberculosis (TB) works against multidrug-resistant strains, potentially inspiring improved treatments and drug development strategies.
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Study identifies ‘Achilles heel’ of drug-resistant pathogens
A study has found a highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, using a genetic platform to identify biological pathways in a drug-resistant strain of the bacterium that are highly sensitive to inhibition.
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Study identifies potential novel drug to treat tuberculosis
A new study demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant strains.
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Plant compound used in traditional medicine may help fight tuberculosis
A compound found in African wormwood — a plant used medicinally for thousands of years to treat many types of illness — could be effective against tuberculosis, according to a new study.
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Researchers discover mechanism driving immune perturbations after severe TB infections
Rsearchers have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.
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Marine sponge microbe provides insights into the evolution of tuberculosis
The surprising discovery of a bacterium in a marine sponge from the Great Barrier Reef with striking similarity to the pathogen responsible for tuberculosis (TB) could unlock and inform future TB research and treatment strategies.