All Mycobacterium tuberculosis articles
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NewsSelf-destructing vaccine offers enhanced protection against tuberculosis in monkeys
A self-destructing vaccine administered intravenously provides additional safety and protection against tuberculosis (TB) in macaque monkeys, suggests new research.
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NewsTuberculosis strains resistant to new drugs are transmitted between patients
Researchers have identified 514 Mycobacterium tuberculosis strains that are resistant to TB drugs, including both old and new treatment regimens, in 27 countries across four continents. 28% of these strains were transmitted directly from one patient to another.
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NewsSystem to auto-detect new variants will inform better response to future infectious disease outbreaks
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.
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NewsPeat-bog fungi produce substances that kill tuberculosis-causing bacteria
An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to the bacterium that causes the human disease tuberculosis.
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NewsResearchers reveal why a key tuberculosis drug works against resistant strains
Research has uncovered why a relatively new antibiotic for tuberculosis (TB) works against multidrug-resistant strains, potentially inspiring improved treatments and drug development strategies.
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NewsStudy identifies ‘Achilles heel’ of drug-resistant pathogens
A study has found a highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, using a genetic platform to identify biological pathways in a drug-resistant strain of the bacterium that are highly sensitive to inhibition.
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NewsStudy identifies potential novel drug to treat tuberculosis
A new study demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant strains.
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NewsPlant compound used in traditional medicine may help fight tuberculosis
A compound found in African wormwood — a plant used medicinally for thousands of years to treat many types of illness — could be effective against tuberculosis, according to a new study.
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NewsResearchers discover mechanism driving immune perturbations after severe TB infections
Rsearchers have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.
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NewsMarine sponge microbe provides insights into the evolution of tuberculosis
The surprising discovery of a bacterium in a marine sponge from the Great Barrier Reef with striking similarity to the pathogen responsible for tuberculosis (TB) could unlock and inform future TB research and treatment strategies.
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NewsNew findings on TB could change how we treat inflammatory disorders
Researchers have found rare mutation that leaves its carriers much more likely to become ill with TB—but, curiously, not with other infectious diseases, potentially upending long-held assumptions about the immune system.
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NewsSuper cally molecules take down tuberculosis
Researchers have identified and synthesised a group of molecules that can act against the cause of tuberculosis in a new way. The callyaerins act against TB by employing a fundamentally different mechanism compared to antibiotic agents used to date.
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NewsResearchers reveals why recombinant BCG induces a stronger and longer-lasting response
Researchers are working on a more potent version of the BCG vaccine that protects against TB. While the conventional immunizer reduced infection by 90% in experiments with mice, the recombinant BCG increased protection rates to 99%.
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NewsNovel 3D hydrogel culture to study TB infection and treatment
Researchers have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment, providing a platform to track and study how tuberculosis bacteria infect lung cells and test the efficacy of therapeutics used to treat TB.
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NewsRecombinant protein offers potential as TB booster vaccine
No new vaccine has yet surpassed BCG, which is a highly effective live vaccine and is very effective in preventing tuberculosis in children. Creating a booster vaccine to strengthen immunity in adults is considered a promising and realistic option.
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NewsUndernourished household members at increased risk for developing TB after exposure
Researchers have found that undernourished household contacts are three times more likely to progress to TB disease.
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NewsResearchers uncover new reasons to target neutrophils for tuberculosis therapy
Using cell models of infection, scientists examined the cross-talk between two lung immune cells: the macrophage and the neutrophil.
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NewsUC San Diego donates blood samples to accelerate Actiphage TB diagnostic study
Sharing samples from a previous study will help to accelerate the development of a blood-based phage diagnostic for tuberculosis. PBD Biotech has asked if more researchers would be prepared to contribute samples they no longer require to help end TB.
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NewsNew classification of tuberculosis supports efforts to eliminate the disease
A new way to classify tuberculosis (TB) that aims to improve focus on the early stages of the disease has been presented by an international team.
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NewsTuberculosis bacteria present in 90% of those with symptoms - including those who test negative
Mycobacterium tuberculosis (Mtb) is present in exhaled breath of 90% of those presenting with suspected tuberculosis. This includes those who were negative on conventional sputum testing and not diagnosed with TB.
