All Mycobacterium tuberculosis articles – Page 3
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News
Researchers develop a new TB vaccine testing model by leveraging old BCG vaccine
Each year, tuberculosis (TB) kills more people than any other infectious disease, falling out of the top spot only temporarily during the COVID-19 pandemic. Source: Saint Louis University Daniel Hoft, M.D., Ph.D., director of the Saint Louis University Center for Vaccine Development Despite TB’s wide reach and ...
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Potential therapeutic target found to combat TB, a disrupted NAD(H) homeostasis
A study shows how Mycobacterium tuberculosis perturbs homeostasis of the high-energy molecule NADH and reprograms glycolysis in myeloid cells - highlighting glycolysis as a potential therapeutic target.
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Cancer therapy shows promise against tuberculosis
A promising new cancer therapy also appears extremely potent against one of the world’s most devastating infectious diseases: tuberculosis (TB).
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New research points out ways to improve tuberculosis vaccines
A new study unveils a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.
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TB vaccine discovery paves path to end no. 1 killer of people living with HIV
Scientists have discovered a tuberculosis (TB) vaccination strategy that could prevent the leading cause of death among people worldwide living with HIV.
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Researchers find chink in the armour of tuberculosis pathogen
Discovery of drug resistance network could clear way for developing a drug to prevent pathogen from resisting and tolerating tuberculosis treatment.
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Careers
World Youth Skills Day 2023 - the inspirational young scientists who are going places
We’re celebrating the upcoming generation of young microbiologists on World Youth Skills Day 2023 by highlighting some of the inspirational student winners of the Grand Awards of Regeneron ISEF 2023.
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Device holds promise for diagnosing TB’s missing millions
Investigators collaborating on new chip-based technology using dielectrophoresis to selectively isolate <i>Mycobacterium tuberculosis</i> from sputum from suspected TB patients in underserved areas report promising results
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AI software at least as good as radiologists at detecting TB from chest X-rays
AI software can accurately detect TB from chest X-rays, a study being presented at this year’s ECCMID shows.
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International consensus highlights importance of molecular testing for AMR in TB management
A multidisciplinary group of tuberculosis experts from the TBnet and RESIST-TB networks have reached a consensus on key issues related to the molecular prediction of Mycobacterium tuberculosis antibiotic sensitivity or resistance and its clinical implications.
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Scientists use non-virulent strain to expose weaknesses in drug-resistant TB
Researchers have discovered new ways to treat antibiotic-resistant strains of tuberculosis (TB), opening the door to new approaches for tackling the disease that kills about 4,000 people a day.
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Europe set to miss 2030 SDG target for ending TB as global threat
A new paper examining progress towards the Sustainable Development Goals target for tuberculosis and associated targets warns that as it stands, the EU/EEA will not reach the set targets by 2030.
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Clinical trial finds temperature-stable TB vaccine is safe and prompts immune response
A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system.
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AutoPLP designs nucleic acid probes to detect rapidly mutating bacteria and viruses
Researchers have developed a procedure that could help researchers catch up to rapidly mutating microbes with an “AutoPLP” technique that designs nucleic acid probes to detect new variants quickly, accurately and easily.
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FDA-approved TB regimen may not work against deadliest form of TB
Investigators say their research indicates a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant (MDR) strains.
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Iron-scavenging endophyte could be newest weapon against resistant TB
An iron-scavenging endophytic bacterium could be the latest class of weapon in the fight against multi-drug resistant tuberculosis, researchers have found.
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New mapping tool delivers first accurate tuberculosis genome
Researchers have developed a novel genome assembly tool that could spur the development of new treatments for tuberculosis and other bacterial infections.
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Scientists reveal protein mechanism behind tuberculosis pathogen success
A group of Chinese scientists has uncovered a previously undefined pathway by which Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), counteracts host immunity.
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