News in AI & in silico
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News
With AI, researchers find increasing immune evasion in H5N1
A new analysis suggests that the H5N1 avian influenza virus is evolving clever strategies. Using artificial intelligence tools, researchers analyzed thousands of viral proteins and found that their bonds to protective antibodies have weakened over time.
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Align announces new collaboration with ATCC to bring AI-ready microbial datasets to life
The Align Foundation has announced a collaboration with ATCC to create the world’s largest public, AI-ready microbial phenotyping dataset.
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Machine learning method helps bring diagnostic testing out of the lab
A new point-of-care biosensing method, dubbed LOCA-PRAM, improves the accessibility of biomarker detection by eliminating the need for technical experts to perform the image analysis.
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Study validates DenovAI’s platform for programmable de novo-designed protein therapeutics
Researchers introduce a new class of experimentally validated AI-driven protein design tools that have the potential to accelerate drug development.
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Scientists team up to identify infectious diseases using AI and hyperspectral imaging
A collaboration will expand patented technology to detect viral signatures in animals. ESS Protect – Animal will offer rapid, non-invasive, and contactless screening for bovine respiratory disease (BRD) using hyperspectral imaging and advanced machine learning.
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AI could accelerate protein engineering – key for developing new medicines
An AI approach developed by researchers from the University of Sheffield and AstraZeneca could make it easier to design proteins needed for new treatments.
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Broad-spectrum coronavirus drug developed through AI-enabled dynamic modeling
Multidisciplinary AI- and physics-driven modeling of the viral fusion process enables discovery of an orally available drug inhibiting infection with multiple coronaviruses.
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Instant AI-assisted test for viral infection
A non-DNA based test could identify viral infections in patients in minutes. Scientists designed a test that confirms the presence of live virus by pushing particles through a nanopore, one at a time, and measuring their electrical conductivity, which varies with size and surface charge as well as the unique molecular structure of the virus.
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New AI reimagines infectious disease forecasting
A new AI tool to predict the spread of infectious disease outperforms existing state-of-the-art forecasting methods. The tool could revolutionize how public health officials predict, track and manage outbreaks of infectious diseases including flu and COVID-19.
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AI-powered framework predicts the evolutionary fitness of SARS-CoV-2 variants
CoVFit is a novel framework designed to predict the fitness of SARS-CoV-2 variants. It integrates molecular data with large-scale epidemiological data to provide a predictive model that helps us understand why some variants succeed while others do not.
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AI predicts bacterial resistance to cleaning agents
With the help of artificial intelligence and DNA decoding, a new method can predict how well disease-causing bacteria such as Listeria tolerate disinfectants. This research may become a valuable weapon in the fight against harmful bacteria.
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Predictive AI model can help build vaccines for future versions of a virus
Researchers have created an AI tool called EVE-Vax that can predict and design viral proteins likely to emerge in the future. For SARS-CoV-2, panels of these “designer” proteins triggered similar immune responses as real-life viral proteins that emerged during the pandemic.
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Breakthrough discovery uses gut bacteria and AI to diagnose a chronic pain syndrome
Scientists have developed AI technology that can detect patterns in gut bacteria to identify complex regional pain syndrome (CRPS) with remarkable accuracy, potentially transforming how CRPS is diagnosed and treated.
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AI plays detective to help scientists find hidden microbes
A team of researchers has created a novel machine learning tool that’s cracking open one of biology’s trickiest puzzles: finding the rarest microbes on Earth. Ulrb not only identifies rare microorganisms but also works with non-microbial data.
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New AI technique can uncover antiviral compounds using limited data
Artificial intelligence algorithms have been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.
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Atomic imaging and AI offer new insights into motion of parasite behind sleeping sickness
Researchers applied leading-edge atomic imaging and AI-driven modeling to create the most detailed 3D map yet of the flagellum on Trypanosoma brucei, which causes sleeping sickness.