All organoids articles
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NewsCancer-fighting bacterial product ‘cocktails’ may offer personalized treatment
Bacteria may be the next frontier in cancer treatment, according to researchers who devised a new approach of creating bacteria-derived mixtures — or cocktails — to help fight bladder cancer. They found that the cocktails significantly boost the immune system’s ability to fight cancer.
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NewsResearchers discover how Ebola and Marburg disrupt the gastrointestinal tract
A new study sheds light on the mechanisms behind the damage caused by Ebola (EBOV) and Marburg virus (MARV) to the gastrointenstinal tract. TIt found that both viruses are capable of infecting and replicating within human gut epithelial cells and that the viruses interfere with the cells’ ability to regulate fluid secretion, mirroring the severe symptoms observed in patients.
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NewsHuman ‘mini-noses’ help understand why RSV infections are more severe in children than in adults
Why does RSV affect babies more severely? To better understand the cellular reasons behind this age-related difference, researchers compared infant and adult human nose organoids, also called mini-noses, regarding their susceptibility and response to infection.
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NewsCedars-Sinai and Exobiosphere partner to launch biomedical research aboard the Haven-1 Space Station
Cedars-Sinai is partnering with Exobiosphere, a company that has developed scientific hardware to automate biomedical research in space and on Earth, and will send experiments to Haven-1, set to become the world’s first commercial space station.
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NewsBacteria deliver synthetic, animal-free way to grow organoids in 3D
Researchers have developed a completely animal-free gel to grow organoids, miniature three dimensional versions of organs. By combining the bacterial protein invasin with a synthetic gel, they created an environment in which organoids can grow and expand long-term.
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NewsNew research uncovers gut microbe-derived metabolites as potential therapy for obesity-related metabolic disorders
New research reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.
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NewsCultured mini-organs reveal the weapons of aggressive Shigella bacteria
Thanks to lab-grown miniature intestines, researchers have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections.
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NewsWorld’s largest bat organoid platform paves the way for pandemic preparedness
Researchers have created the world’s most comprehensive bat organoid platform. These ’mini-organs’ are grown from five common bat species found across Asia and Europe and represent four different organs—airway, lungs, kidneys, and small intestine.
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NewsScientists culture previously uncultivable human rhinovirus C with innovative respiratory organoids
Scientists have successfully utilised human respiratory organoids (mini-organs) established by their team to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.
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NewsBacteria to the rescue: a sustainable solution for growing organoids
Researchers have developed a new way to grow organoids using Invasin, a protein produced by bacteria, offering a sustainable, affordable and animal-free alternative to currently used methods.
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NewsMini lungs make major COVID-19 discoveries possible
Scientists infect miniature lung organoids with the virus responsible for COVID-19, revealing new ways in which the infection spreads and suggesting potential treatments.
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NewsLung organoids unveil secret of how pathogens infect human lung tissue
Using human lung microtissues, researchers have uncovered the strategy used by a dangerous pathogen to invade the lungs. Pseudomonas aeruginosa targets specific lung cells and has developed a sophisticated strategy to break through the lungs’ line of defense.
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NewsLab-grown skin helps unlock secrets of mpox virus infection
A new model system for studying mpox virus infections in the laboratory is providing valuable insights into the virus’s mechanisms of attack on skin cells.
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NewsScientists build human lungs in dish to test drugs
Scientists have developed a step-by-step blueprint to create advanced human lung models in the lab, which they say will accelerate the discovery and development of new drugs and reduce reliance on animal testing.
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NewsEuropean-funded €2.3m project will revolutionize bioprinting of living materials
The PRISM-LT project has received a €2.3 million grant for a five-year program that aims to create an adaptable platform for 3D bioprinting of living tissue with dynamic functionalities and predictable shapes.