All Paneth cells articles
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NewsIntestinal stem cells can fight back against salmonella scientists discover
Researchers have shown that intestinal stem cells can directly sense intracellular Salmonella enterica bacteria and activate an inflammasome-dependent response. Following infection, the stem cells differentiate into antimicrobial Paneth cells, which secrete molecules that help limit bacterial persistence in the intestinal crypt.
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NewsA protein found in the GI tract can neutralize many bacteria
The mucosal surfaces that line the body are embedded with defensive molecules that help keep microbes from causing inflammation and infections. One of these molecules, intelectin-2, has broad-spectrum antimicrobial activity against bacteria found in the GI tract.
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NewsPsoriasis-linked gene mutation also impacts gut health
A mutation previously linked to skin disorders like psoriasis may also play a surprising role in gut health, according to new research. This mutation activates skin immune responses but also affects the intestine, revealing a new connection between genetics, the immune system, and the gut.
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NewsGut hormone doubles as immune regulator for the fungal microbiome
Research shows that a gut hormone called peptide YY also plays a vital role in maintaining the health of the gut microbiome by preventing helpful fungi from turning into more dangerous, disease-causing forms.