All persister cells articles
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NewsNew breakthrough uncovers how to kill ‘zombie’ TB cells resistant to antibiotics
Researchers exposed a library of over 500,000 genetically modified tuberculosis bacteria to two commonly used antibiotics. By analysing the survivors, they pinpointed genes whose disruption significantly reduced the number of surviving persisters.
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NewsResearch identifies new trigger accelerating antibiotic resistance
A new study shows that ciprofloxacin, a staple treatment for urinary tract infections, throws Escherichia coli (E. coli) into an energy crisis that saves many cells from death and speeds the evolution of full‑blown resistance.
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NewsNew study uncovers mechanisms of bacterial dormancy involving protein aggregation
Researchers have revealed a mechanism involving protein aggregation that allows bacteria to enter a dormant state, a phenomenon that is associated with the persistence of infections and the challenge of antibiotic resistance.
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NewsScientists reveal role of notorious cell subpopulation in antibiotic failure
Scientists provide the best evidence to date for the significance of bacterial persister cells in the failure of antibiotics in the clinic.
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NewsUltrasound helps break bacterial barriers in chronic treatment-resistant wounds
Researchers have developed a new strategy combining palmitoleic acid, gentamicin, and non-invasive ultrasound to improve drug-delivery into chronic wound infections.