All Rosa Vincent articles
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NewsEngineered bacteria paint targets on tumors for cancer-killing T cells to see
Columbia engineers are the first to program bacteria to act as beacons that guide the activity of engineered T cells. This work is also the first to design interactions between these two “living” medicines to enable targeting of a range of solid tumor.
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NewsEngineered bacteria guide CAR-T cells to poorly infiltrated solid tumors
A new probiotic-guided chimeric antigen receptor (CAR)-T platform uses engineered bacteria to infiltrate and produce synthetic antigen targets, enabling CAR-T cells to find, identify, and destroy tumor cells in situ, according to a new study.
