All Singapore-MIT Alliance for Research and Technology articles
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News
Researchers develop UV and machine learning-aided method to detect microbial contamination in cell cultures
This is the first novel technology that utilises machine learning to analyse unique ultraviolet light “fingerprints” on cell cultures to quickly identify the presence of contamination.
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News
Breakthrough research identifies mechanism behind drug resistance in malaria parasite
A new study has found that a cellular process called transfer Ribonucleic acid (tRNA) modification influences the malaria parasite’s ability to develop resistance to Artemisinin-based combination therapies.
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Researchers uncover novel bacterial communication system to combat AMR
Using a sophisticated mass spectrometry technology developed at SMART and MIT, researchers have discovered that the enzyme RlmN is a stress sensor for reactive oxygen species (ROS) – highly reactive molecules which can cause damage to bacteria. Source: SMART AMR (L to R) SMART researchers Dr Cui Liang, ...
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Novel combination therapy counters antibiotic-resistant Mycobacterium infections
Researchers have discovered a novel therapy by combining two antibiotics, rifaximin and clarithromycin, to treat Mycobacterium abscessus, a non-tuberculous mycobacterium (NTM) that causes chronic lung-related infections.
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Scientists develop novel combination therapy for treating vancomycin-resistant bacterial infections
Researchers have developed a novel combination therapy using an anticancer agent, mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating bacteria that are resistant to the vancomycin.