All Staphylococcus aureus articles
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New agent inhibits Staphylococcus aureus toxin – hope for pneumonia patients
Researchers have developed a miniaturized test system that allowed them to screen over 180,000 compounds for their ability to block the effect of the key virulence factor α-hemolysin in S aureus. Drug candidates from the quinoxalinedione class, in particular the compound H052, proved to be highly effective, both in cell culture and in animal models.
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Purified immunoglobulin F(ab′) 2 prevents lethal staphylococcal enterotoxin B intoxication in mice and rhesus monkeys
Purified F(ab′)2 fragments are an effective antidote to lethal SEB doses in mice and rhesus monkeys, and therefore might be a favorable candidate for treating patients with severe SEB intoxication, a new study suggests.
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Throat microbiome holds clues to older Australians’ health
A simple swab from the back of the throat, known as the oropharynx, may offer clues about health challenges faced by aged care residents.
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Reactive nitrogen species dominance is key in the fight against antimicrobial resistance
The balance between two types of molecules – reactive nitrogen species (RNS) and reactive oxygen species (ROS) – plays a crucial role in tackling drug-resistant bacteria, according to a new study.
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Researchers uncover how Staphylococcus aureus ‘steals’ iron from our blood during infections
Researchers have revealed how Staphylococcus aureus bacteria extract iron from hemoglobin – a process crucial to their survival during infections. The study has identified the full sequence of protein–protein interactions during this iron ‘theft’.
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Ventilation fans can significantly lower the risk of inhaling bacteria particles after toilet flushing
New research finds that unhealthy concentrations of bacteria are released into the air by toilet flushing - but active ventilation with an exhaust fan reduce the risk by 10 times.
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Dangerous bacteria lurk in hospital sink drains, despite rigorous cleaning
Even in modern hospitals, drains can serve as reservoirs for known and novel pathogens, according to a new study.
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Diabetes can drive the evolution of antibiotic resistance, study reveals
A new study shows that people with diabetes are more likely to develop antibiotic-resistant strains of Staph. The results show how the diabetic microbial environment produces resistant mutations, while hinting at ways antibiotic resistance can be combatted in this patient population.
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Turmeric teamed with light can help ward off superbugs
In a new study, researchers have evaluated a low-cost yet effective technology called photodynamic inactivation using curcumin to curb bacterial resistance.
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Why some kids get sicker: The hidden power of nose bacteria
A scoping review unravels how bacterial colonization in the respiratory tract impacts both the severity of respiratory syncytial virus (RSV) infections and long-term respiratory health in children.
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Delicate nanoflower is deadly to bacteria
A carnation-like nanostructure could someday be used in bandages to promote wound healing. Researchers report that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, anti-inflammatory and biocompatible properties.
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Why you shouldn’t scratch an itchy rash: New study explains
New research uncovers how scratching aggravates inflammation and swelling in a mouse model of a type of eczema called allergic contact dermatitis.
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CARB-X funds Rhode Island Hospital to assess feasibility of direct from blood detection of bacterial pneumonia
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award Rhode Island Hospital at Brown University Health US$1M to demonstrate proof-of-concept of a polymerase chain reaction (PCR) approach informed by RNA sequencing to detect bacterial pneumonia directly from whole blood.
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Sophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
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$7 Million grant to tackle lung infections through innovative probiotic treatment
The PROTECT project seeks to combat lung infections by assembling a community of beneficial lung microbes that can outcompete harmful pathogens.
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Scientists can pinpoint bacterial needle in haystack using fluorescence
Bacterial troublemakers are able to survive antibiotics and are not detected by diagnostic antibiotic resistance testing. A new method has been developed to look at single bacteria and to find the antibacterial resistant ones, or the troublemakers, among them.
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Researchers to study how much MRSA is lurking in the air in hospitals
Scientists are working to minimize health care workers’ exposure to MRSA, or methicillin-resistant Staphylococcus aureus, a type of staph bacteria that’s become resistant to many of the antibiotics used to treat ordinary staph infections.
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Innovative implant material combines osteogenic and antibacterial properties for superior bone repair
A new study introduces a novel polyetheretherketone (PEEK)-based implant material that not only promotes bone growth but also possesses potent antibacterial capabilities.
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Multi-disciplinary team awarded $3.9 million to study mixed fungal-bacterial infections
A multi-disciplinary team was recently awarded $3.9 million from the National Institute of Allergy and Infectious Diseases for a project aimed at unravelling intricate mysteries surrounding complex fungal-bacterial infections.
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Nasal microbiome: friendly pirates deprive multi-resistant bugs of iron
A new study reveals that whether dangerous staphylococci survive in the nose depends on what other bacteria are present – and how they obtain iron.