All typhoid fever articles
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News
New vaccine shows promise against typhoid and invasive salmonella in first human trial
Researchers have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella–two major causes of illness and death among children in sub-Saharan Africa.
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News
Survival trick: Pathogen taps iron source in immune cells
The body defends itself against pathogens by depriving them of vital iron. However, researchers have discovered that Salmonella bacteria specifically target iron-rich regions within immune cells to replicate, evading the immune defense.
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Study identifies surge in antibiotic-resistant typhoid
Researchers used whole genome sequencing to identify that S Typhi isolates with mutations evolved locally from the endemic S Typhi population in Blantyre, Malawi, and were not the result of importations from other countries.
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Environmental monitoring offers low-cost phage tool for typhoid fever surveillance
Researchers can accurately track where typhoid fever cases are highest by monitoring environmental samples for bacteriophages that specifically infect the bacterium that causes typhoid fever.