All UK & Rest of Europe articles – Page 39
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News
Antibiotic ‘Velcro’ gives bacteria a sticky situation
A small antibiotic called plectasin uses an innovative mechanism to kill bacteria. By assembling into large structures, plectasin latches onto its target on the bacterial cell surface - scientists have now mapped how this bond is formed.
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New small molecule found to suppress the evolution of antibiotic resistance in bacteria
Researchers have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.
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Ancient viral DNA in the human genome linked to major psychiatric disorders
New research led by King’s College London has found that thousands of DNA sequences originating from ancient viral infections are expressed in the brain, with some contributing to susceptibility for psychiatric disorders such as schizophrenia, bipolar disorder, and depression. Published in Nature Communications, the study was part-funded ...
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New tool may help prioritize high-risk infants for RSV immunization
On the heels of a shortage of nirsevimab for infant respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) prevention, a new tool may help identify newborns at highest risk for developing serious infections.
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Researchers uncover two new mechanisms behind antibiotic resistance
Two newly discovered mechanisms in bacteria have been identified that can contribute to the development of antibiotic resistance. Source: Uppsala University Helen Wang, Senior Lecturer and Docent at the Department of Medical Biochemistry and Microbiology, Uppsala University Changing the number of copies of resistance genes in bacteria ...
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Sea zombies: Viruses keep the most common marine bacteria in check
The ocean waters surrounding the German island of Helgoland provide an ideal setting to study spring algae blooms, a focus of research at the Max Planck Institute for Marine Microbiology since 2009. Source: Jan Brüwer/Max Planck Institute for Marine Microbiology Sunset over the island of Helgoland in ...
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Mystery CRISPR unlocked: A new ally against antibiotic resistance?
CRISPR-Cas systems are bacterial adaptive immune systems that target and cut the nucleic acids (DNA/RNA) of invading genetic parasites like bacteriophages (phages); viruses that infect - and eventually kill - bacterial cells. They consist of two main components; the CRISPR array, which stores immune memory of past ...
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AI reveals critical gaps in global Antimicrobial Resistance research
Researchers developed global maps showcasing regional, methodological, and sectoral AMR research activities, confirming a lack of interdisciplinary collaboration, particularly in low-income countries, where the burden of increasing AMR is most acute.
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Researchers may have come up with second chance for antibiotic agent
A new study focuses on the protein peptide deformylase (PDF), which is involved in protein maturation processes in bacterial cells. While the original drug candidate had to be discarded, modification of the molecule could offer a second chance.
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Scientists figure out how to maximise beneficial compounds in blueberry wine
Researchers examined fermentation’s effects on the bioactive compounds and antioxidant activity in blueberry wine. The results suggest blueberry wine maintains some of the fruit’s nutrients and the team identified ways to optimize components in this superfood tipple.
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Study paves the way for an active agent against hepatitis E
Tests in cell culture with human liver cells showed that the compound K11777 prevents infection with hepatitis E viruses.
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HPV vaccine prevents most cervical cancer cases in more deprived groups, major study shows
The human papillomavirus, or HPV, vaccine is cutting cases of cervical cancer right across the socio-economic spectrum, with most cases being prevented in more deprived groups, according to a major study funded by Cancer Research UK. Source: NIAID Colorized electron micrograph of HPV virus particles harvested and ...
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Wearing face masks did not reduce risk of COVID infection after first Omicron wave, research shows
A study has found that wearing face masks did not lower the risk of Covid infection following the initial surge of the Omicron variant. Overseas travel was not associated with increased risk prior to February 2022, but then became a significant risk.
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Your Pseudomonas aeruginosa biofilm may vary - depending on where it turns up
The bacterium Pseudomonas aeruginosa adapts its biofilm form depending on the infectious site where it is found, potentially affecting antibiotic sensitivity, according to new research being presented at the Letters in Applied Microbiology ECS Research Symposium today.
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New method can help scan for new viruses on the horizon
The exchange of genetic material between different virus species can lead to the sudden emergence of threatening pathogens with significantly altered characteristics, new current genetic analyses suggests.
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Enzyme that reproduces Meinwald reaction offers hope as bionanomachine for green chemistry
Researchers have for the first time precisely characterised the enzyme styrene oxide isomerase, which can be used to produce valuable chemicals and drug precursors in an environmentally friendly manner.
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Scientists uncover mechanism that could weaken virulence of Pseudomonas aeruginosa
Researchers have found a mechanism that makes it possible to weaken the virulence of opportunistic bacterial pathogen Pseudomonas aeruginosa - based on this knowledge, a new approach for antibiotics can be developed.
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Careers
Endophytic fungi yield vivid colours and vital bioactive compounds
Endophytic fungi from the forests of Poland are yielding up a treasure trove of compounds that could revolutionize the pharmaceutical and biotechnological industries, according to Applied Microbiology International member Dr El-Sayed R El-Sayed.
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Birth by C-section more than doubles odds of measles vaccine failure
Researchers say it is vital that children born by caesarean section receive two doses of the measles vaccine for robust protection against the disease.
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Researchers advise reviewing temperature control measures in hospitals to manage legionella
A new study has yielded significant findings on the survival of the Legionella pneumophila bacterium in hospital water systems.