All USA & Canada articles – Page 86
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NewsDrug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy
Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens.
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NewsNew disease testing component facilitates lower-cost diagnostics
Biomedical researchers have developed a new, less expensive way to detect nuclease digestion – one of the critical steps in many nucleic acid sensing applications, such as those used to identify COVID-19 and other infectious diseases.
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NewsMosquito thermal adaptation could shift patterns of disease spread under climate change
Thermal adaptation can determine their risk of transmitting mosquito-borne diseases and how this risk might change in the future as they respond to climates warming.
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NewsVaping can increase susceptibility to infection by SARS-CoV-2
Vapers are susceptible to infection by SARS-CoV-2, the virus that spreads COVID-19 and continues to infect people around the world, a new study has found.
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NewsBCG mechanism extends protection to beat influenza A
A new study uncovered a previously unknown mechanism that extends the BCG vaccine’s shield to combat influenza A virus—the most prevalent flu strain.
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NewsResearchers team up to publish bile acid breakthrough
Scientists have uncovered a previously unknown way that the microbes living in our gut help to make bile acids.
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NewsSpace-grown antiviral drug successfully brought back to earth in private Varda Space capsule
Space-grown crystals of an antiviral drug have been brought to earth following the successful recovery of the capsule from Varda Space Industries’ W-1 mission.
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NewsCOVID vaccine during pregnancy improves neonatal outcomes
A study has found that neonates of booster-vaccinated mothers had less risk of being infected with COVID-19 compared to those of unvaccinated mothers. Neonates of unvaccinated mothers died twice as frequently as those of vaccinated mothers.
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NewsStreams connected to groundwater show improved detoxification and microbial diversity
Streams with ample connections to shallow groundwater flowpaths have greater microbial diversity and are more effective at preventing toxic forms of metals—often products of upstream mining—from entering and being transported downstream.
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NewsMice study suggests metabolic diseases may be driven by gut microbiome, loss of ovarian hormones
The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent study.
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NewsCopies of antibiotic resistance genes greatly elevated in humans and livestock
Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. The research shows bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance ...
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NewsComplement system response to AAV vector gene therapy
Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer – activation of the complement system.
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NewsNew method detects pathogens faster and more accurately by melting DNA
A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, producing results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
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NewsStudy of usefulness of lockdowns during epidemics identifies alternate solution
Researchers found that small nonpharmaceutical interventions can tip the optimal response between very different approaches to slowing viral spread and identified an alternate approach that has previously not been recognized as effective.
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NewsResearchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
A new class of antibiotics not only shows promise against a broad array of bacterial infections but can also evade the dreaded resistance that has been rendering our current generation of first-line antibiotics ineffective.
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NewsLong-acting HIV treatment demonstrates efficacy in people with challenges taking daily medicine as prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen, according to interim data from a randomized trial. Source: NIAID Colorized transmission electron micrograph ...
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NewsScientists win $434k grant to induce microbes to desert their protective biofilm
Researchers are pursuing biofilm dispersal agents such as specific enzymes in hopes the enzymes can induce microbes to leave the safety of the protective biofilm and become more susceptible to antibiotics.
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NewsUptake of HIV prevention medication doubles with mix of digital health interventions
A combination of interventions of one-on-one telehealth coaching, peer support forums, and automated text messages more than doubled the use of the HIV prevention strategy, called PrEP, among younger, at-risk Americans.
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NewsBat mating swarms may be the key to solving the next pandemic
The evolution of viral tolerance in Myotis bats may help scientists prevent future pandemics, say researchers.
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NewsFatty acid produced by gut bacteria directly influences fat metabolism in animals
Researchers investigating gut bacteria that produce fatty acids with a special chemical structure, known as a cyclopropane ring, showed that these can be converted into signals that turn on fat desaturation in the nematode C. elegans.