All Vaccinology articles – Page 16
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NewsIntranasal COVID-19 vaccine headed to clinical trials
CyanVac will sponsor a randomized, double-blind Phase 2b study to compare the efficacy and safety of CVXGA, its intranasal vaccine candidate designed to protect against COVID-19, against an FDA-approved mRNA-based COVID-19 vaccine.
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NewsFeeling rough after your COVID shot? That means it’s working!
Side effects of the Covid vaccine may include tiredness, muscle and joint pain, chills, headache, fever or nausea, but a new study finds that the symptoms indicate a robust immune response that is likely to lessen the chances of infection.
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NewsStudy finds no association between COVID-19 vaccines and stillbirths
In a new study funded by the U.S. Centers for Disease Control and Prevention, researchers found “no association between COVID-19 vaccination and stillbirth”.
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NewsItaly pertussis outbreak hospitalises 108 and claims 3 lives
A significant pertussis outbreak, predominantly affecting neonates and young infants, saw 108 hospitalisations and three deaths. Its resurgence may be attributed to limited maternal immunisation during pregnancy and increased circulation post-COVID-19 pandemic.
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NewsVaccine approach offers promise to induce longer-lasting protective immunity against COVID-19
A scientific team has engineered a COVID-19 vaccine that induced – in pre-clinical models – very long-lasting, protective immunity against SARS-CoV-2 virus with a single-shot immunisation.
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NewsFalse belief in MMR vaccine-autism link endures as measles threat persists
As measles cases rise across the United States and vaccination rates for the MMR (measles, mumps, rubella) vaccine fall, a new survey finds that a quarter of U.S. adults do not know that claims that the MMR vaccine causes autism are false.
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News$1.3m funding will help scientists to contribute to the eradication of polio
Scientists have received a $1.3 million grant from the Bill & Melinda Gates Foundation to develop and validate a novel and safe approach for measuring immune responses to polioviruses.
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NewsNewly isolated antibodies may aid effort to fight influenza B
Researchers have isolated human monoclonal antibodies against influenza B, a significant public health threat that disproportionately affects children, the elderly and other immunocompromised individuals.
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NewsNovel vaccine concept generates immune responses that could produce multiple types of HIV broadly neutralizing antibodies
Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals’ immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs). The findings, published in Nature Immunology, are an encouraging, incremental step in developing a preventive HIV vaccine. ...
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NewsKnowledge is a factor in closing black-white COVID-19 vaccination gap
Early in the Covid-19 pandemic, Black Americans were more hesitant to take the Covid-19 vaccine than were White Americans. As the pandemic went on, however, the disparity in vaccination rates between Black and White adults declined. Source: Baltimore County Government People queueing to be vaccinated, 23 December 2020 ...
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NewsEffectiveness of updated COVID-19 vaccines wanes moderately over time, is lower against currently circulating variants
New research shows boosters targeting omicron subvariants of SARS-CoV-2 are still providing reasonably durable protection against infection, hospitalization and death from COVID-19, but are less protective against the JN.1 strain.
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NewsResearchers take step toward development of universal COVID-19 antibodies
Scientists have developed a promising new human monoclonal antibody that appears a step closer to a universal antibody cocktail that works against all strains of SARS-CoV-2.
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NewsScientists uncover factors potentially contributing to the decline of the mpox outbreak
Researchers hypothesise that it is not likely that preventive vaccination was a driver of the outbreak’s decline in the Netherlands, as the mpox incidence started to decline before the start of the vaccination programme.
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NewsVaccine development program aims to prevent sepsis in newborns
Researchers have been awarded $3.96 million to develop a maternal vaccine that prevents sepsis caused by Klebsiella pneumoniae in newborns and infants.
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NewsNew viral strain induces immunogenic cell death in tumour cells
A study has developed a new strain of vaccinia virus, which can replicate in tumour cells while maintaining increased immunogenicity. Specifically, it can to induce so-called immunogenic cell death in tumour cells.
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NewsResearchers develop experimental mRNA avian flu vaccine
An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models, according to a new study.
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NewsCentury-old vaccine protects type 1 diabetics from infectious diseases
Research shows that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
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NewsDrug-like inhibitor shows promise in preventing flu
Scientists have developed a potential drug-like molecule that blocks the first stage of type A influenza infection.
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NewsNew tool may help prioritize high-risk infants for RSV immunization
On the heels of a shortage of nirsevimab for infant respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) prevention, a new tool may help identify newborns at highest risk for developing serious infections.
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NewsResearchers deliver boost for HIV vaccine research
Scientists have developed a comprehensive platform for HIV vaccine research capable of both preclinically validating next-step boost immunogens and providing new insights into the basic biology of the antibody response.