All Vibrio cholerae articles
-
NewsResearchers discover first PLP-dependent enzyme that influences bacterial protein production
Researchers discovered aminovaleramididine synthetase (AvaS), the first pyridoxal phosphate (PLP)-dependent enzyme involved in tRNA modification, expanding scientific understanding of how RNA shapes the reading of genetic information. The discovery reveals a previously unknown mechanism that bacteria use to regulate protein production.
-
NewsA fourth T6SS in clinical Pseudomonas aeruginosa deploys the pore-forming effector TseMt
The hospital-associated pathogen Pseudomonas aeruginosa has type VI secretion systems (T6SSs). Most reference strains encode three T6SSs, but comparative genomics has identified an additional H4-T6SS in a subset of clinical isolates.
-
NewsBiologists uncover a molecular mechanism that helps bacteria spread antibiotic resistance genes
A new study reveals the molecular mechanism behind one of the most powerful mechanical actions in all of biology, the reeling in of tiny surface fibers called type IV pili.
-
NewsHidden small RNA determines if cholera bacterium can infect humans
Scientists have uncovered what gives Vibrio cholerae, the bacterium that causes cholera, the ability to colonize the human gut. They found that a small RNA embedded within another gene controls where cholera thrives, a discovery that could improve prediction and prevention strategies.
-
NewsHow cholera bacteria swap defenses against viruses
To survive viral attack, bacteria equip themselves with antiviral immune systems. Vibrio cholerae carries a large genetic element called a sedentary chromosomal integron (SCI). A new study investigates whether the SCI might capture gene cassettes from genetic material entering the cell from the outside.
-
NewsOne of cholera’s great enemies is found in the human gut
Cholera-causing bacteria are locked in an evolutionary arms race with a viral nemesis, according to a new genomic study. Researchers found that in the Ganges Delta, cholera bacteria rapidly gain and lose special armour that protects against attacks from the virus, known as bacteriophage ICP1.
-
NewsBacterial hitchhikers can give their hosts super strength
Molecular hitchhikers living within bacteria can make their hosts extra resistant to medical treatment by corralling them into tightly packed groups. The study introduces a previously unknown avenue through which bacterial infections can become more difficult to treat.
-
NewsA bacterial toxin can counteract colorectal cancer growth
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. Systemic administration of the purified bacterial substance changes the immune microenvironment in tumours.
-
NewsA new study reveals how cholera virulence is activated
A new study provides a long-sought structural explanation of the regulatory cascade that allows Vibrio cholerae to colonize the human gut and produce the cholera toxin that causes life-threatening diarrhea.
-
NewsCholera vaccine completes phase 1 trial
A clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide.
-
NewsSugar transporter discovery offers promising avenue for improving antibiotic efficacy
Scientists have recently demonstrated that aminoglycosides enter bacteria by using sugar transporters. They have also successfully doubled the number of transporters, even in the most resistant Escherichia coli strains, thus improving antibiotics’ penetration rate and efficacy.
-
NewsStudy shows mucus contains molecules that block Salmonella infection
Researchers have identified mucins that defend against Salmonella and other bacteria that cause diarrhea. They now hope to mimic this defense system to create synthetic mucins that could help prevent or treat illness in soldiers or other people at risk of exposure to Salmonella.
-
NewsNew mechanisms for bacterial motility and DNA transfer between bacteria decoded
Scientists have discovered a new family of signaling proteins, widespread in the bacterial kingdom and contributing to regulating bacterial motility and DNA uptake mechanisms.
-
NewsCholera vaccination campaign launched in Darfur to protect over 1.8 million people
A cholera vaccination campaign kicked off on 21 September 2025 in South Darfur, marking the start of a campaign that aims to reach 1.86 million people aged one year and older with oral vaccines in response to the ongoing outbreak.
-
NewsAn oral cholera vaccination campaign aims to reach more than 2.6 million people in Sudan’s Khartoum State
A 10-day reactive oral cholera vaccination campaign, launched on 10 June in 5 localities in Sudan’s Khartoum State, aims to protect more than 2.6 million people aged 1 year and above from cholera infection, interrupt transmission and help contain the cholera outbreak.
-
NewsScientists uncover how certain cholera strains are so successful at evading phage attacks
A new study shows that a virulent lineage of cholera acquired multiple distinct bacterial immune systems that have protected it from diverse types of phages. This defense may have contributed to the massive scale of the Latin American epidemic.
-
NewsPatients with multi drug-resistant cholera in Europe linked to exposure to contaminated holy water from Ethiopia
Exposure to holy water from Ethiopia has recently been linked to several cases of cholera in the UK and Germany with a multidrug-resistant Vibrio cholerae strain, according to a new study.
-
NewsSophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
-
NewsBad bacteria can trigger painful gut contractions; new research shows how
After a meal of questionable seafood or a few sips of contaminated water, bad bacteria can send your digestive tract into overdrive. Your intestines spasm and contract, efficiently expelling everything in the gut. Source: Parthasarathy Lab and Guillemin Lab Immune cells (magenta) and cells expressing a reporter of ...
-
NewsFrom Yemen to Mayotte, the spread of a highly drug-resistant cholera strain
Scientists have revealed the spread of a highly drug-resistant cholera strain. The strain is resistant to ten antibiotics – including azithromycin and ciprofloxacin, two of the three recommended for treating cholera – and was identified for the first time in Yemen in 2018-2019.