All Wellcome Sanger Institute articles
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Specific nasal cells protect against COVID-19 in children
Important differences in how the nasal cells of young and elderly people respond to the SARS-CoV-2 virus, could explain why children typically experience milder COVID-19 symptoms, a new study finds.
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Lives could be saved from tropical disease with new rapid test
A new test diagnoses patients with melioidosis within hours, rather than days, meaning they can receive the correct antibiotics faster.
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Antibiotic use is not the only driver of superbugs
Researchers have analysed the rise of antibiotic resistance over the last 20 years in the UK and Norway, highlighting that antibiotic use is not the only factor in the increase.
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Pocket-sized DNA sequencers track malaria drug resistance in Ghana in near real-time
A team of scientists working in Ghana have pioneered on-site genomic surveillance to track changes in the malaria parasite, achieving sampling to sequencing within 48 hours. This will guide local interventions and policy in near real-time.
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Antibiotic-resistant bacteria mapped in Ghana
The first genomic surveillance of Klebsiella bacteria in Ghana has shown that heavily antibiotic-resistant pathogens are only found in hospital settings, an insight which could be used to help inform control measures.
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Genes fuelling antibiotic resistance in Yemen cholera outbreak uncovered
Widespread antibiotic resistance among cholera-causing bacteria causing the outbreak in Yemen since 2018 explained by gene mixing.
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Syphilis transmission networks and AMR in England uncovered using genomics
Scientists use genomics to uncover syphilis transmission patterns in England, in a pioneering new approach for STI surveillance.
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New cholera substrains in Bangladesh uncovered by genomic surveillance
Researchers have uncovered two new cholera substrains in a displaced refugee population in southern Bangladesh, where a pre-emptive mass vaccination campaign of over one million refugees was successful in preventing an epidemic.
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Mapping evolution of E. coli virulence factor offers refined drug target
Researchers have presented evidence that targeting the K1 capsule can be used as the basis of treatment, paving the way to prevent serious E. coli infections.
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Second gene implicated in malaria chloroquine resistance evolution
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, scientists have shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.
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Hospitals are riskier than farms when it comes to superbug transmission - but beware your pet
A deadly drug resistant bacterium that rivals MRSA is found in livestock, pets and the wider environment, but is rarely transmitted to humans through this route, scientists have found.