Young Innovators & Early Career Research
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Researchers identify critical immune factor for host defense against MRSA
Researchers identify a critical immune factor for host defense against MRSA, offering a potential explanation for failures of previous vaccine strategies and a proposal for a new direction for tackling this bacterium.
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Fred Hutch launches Atlas of Inspiring Hispanic/Latinx Scientists
To highlight and celebrate the many contributions of Hispanic and Latinx scientists, Fred Hutch Cancer Center has launched an Atlas of Inspiring Hispanic/ Latinx Scientists.
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Plant prebiotics offer new ally in the fight against pathogens
Disruptions to the community of microbes that live inside the leaves of a spindly plant called <i>Arabidopsis</i> can compromise a plant’s ability to tell harmless invaders from harmful ones – effectively turning the plant’s defensive arsenal against itself.
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Gut microbiome influences location and type of immune cells
Researchers have found that different anatomical sections of the gastrointestinal tracts of mice carry different compositions of microbial communities, and the specific makeup of the microbiota can influence the type and abundance of immune cells in any particular region.
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Newly discovered antimicrobial could prevent or treat cholera
Natural antimicrobials called microcins are produced by bacteria in the gut and show promise in fighting infection. A study identifies the first known microcin that targets the strains of bacteria that cause cholera.
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New phage editing technology could lead to alternative treatments for antibiotic-resistant bacteria
Scientists have developed a technology that lets them edit the genomes of phages in a streamlined and highly effective way, giving them the ability to engineer new phages and study how the viruses can be used to target specific bacteria.
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Wound peptides can help detect dangerous infections more quickly
After identifying unique peptide patterns and changes in these patterns based on different types of bacteria in wounds, researchers can now assess the severity of the infection, a new study reveals.
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Game-changing purple bacteria can become bioplastic factories
Two new studies highlight one potential source of game-changing materials: purple bacteria that, with a little encouragement, can act like microscopic factories for bioplastics.
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Researchers discover key gene regulating virulence of fungus that causes severe lung infections
Scientists have found a potential target for novel therapeutic strategies to combat fungal infections caused by Aspergillus fumigatus and are now looking for a molecule that inactivates the protein expressed by the gene as a basis for a drug.
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Severe COVID-19 can involve either exacerbated lung inflammation or high viral replication
Researchers report a study based on autopsies of 47 patients who died after being infected by the ancestral strain of SARS-CoV-2. The findings will support clinical decisions on the treatment of critical cases.
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Scientists unlock the secret behind a decades-old dengue mystery
A study has pinpointed a mutation in the dengue virus’ genome as the root cause of a 1970s outbreak of dengue in the South Pacific, which impaired the virus’ ability to replicate in human cells, resulting in a low virus load and asymptomatic infections in patients.
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Waging war on ‘superbugs’ in aged care
A new study explores the link between the widespread use of antibiotics in residential aged care and the resulting antibiotic resistant bacteria in the gut that can be passed on to other residents
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New discovery of how bacteria navigate their environment could change how we treat infection
Scientists have found that bacteria can directly measure differences in chemical concentration across the length of their cell bodies, contrary to decades of established scientific belief.
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Scientists unveil first complete image of the PARIS system
A new study explores the PARIS immune system, which bacteria use to protect themselves against viral infections and which stands for Phage Anti-Restriction Induced System.
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A human-centered AI tool to improve sepsis management
A proposed artificial intelligence tool to support clinician decision-making about hospital patients at risk for sepsis has an unusual feature: accounting for its lack of certainty and suggesting what data it needs to improve its predictive performance.
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Creature the size of a dust grain found hiding in California’s Mono Lake
Researchers have now found an unusual creature lurking in the shallows of Mono Lake — a choanoflagellate that could tell scientists about the origin of animals more than 650 million years ago.
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CRISPR gene scissors switch off with built-in timer
Researchers have discovered a timer integrated into the CRISPR gene scissors that enables the gene scissors to switch themselves off.
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New method pinpoints virus that targets Ecuador fruit crop
Scientists in Ecuador have developed a new method to detect and diagnose a virus that devastates crops of babaco, a fruit plant of economic importance to local farmers.
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Scientists uncover how microbial enzymes lap up carbon dioxide
The remarkable affinity of the microbial enzyme iron nitrogenase for the greenhouse gas CO2 makes it useful for future biotechnology, a new study suggests.
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Nanoparticle platform offers step toward more effective Covid and HIV vaccines
Researchers have developed a nanoparticle platform that could make existing vaccines more effective, including those for influenza, COVID-19, and HIV.